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gastroenterology

Practice targeted AMC-style multiple-choice questions on gastroenterology.

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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old male presents with intermittent abdominal pain and melena. The provided image was obtained. What is the most likely underlying cause?

A. Henoch-Schönlein purpura
B. Cystic fibrosis
C. Meckel's diverticulum
D. Peutz-Jeghers syndrome
E. Blue rubber bleb nevus syndrome
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 38-year-old male presents to the emergency department with a 2-day history of intermittent abdominal pain, nausea, and vomiting. He reports passing dark, tarry stools. He has a known history of multiple cutaneous hemangiomas since childhood. On examination, his abdomen is distended and tender to palpation, particularly in the periumbilical region. Bowel sounds are hyperactive. Vitals are: HR 110 bpm, BP 100/60 mmHg, RR 20 breaths/min, SpO2 97% on room air, Temp 37.2°C. A CT scan of the abdomen and pelvis is performed, and a representative image is shown. Given the clinical presentation and imaging findings, what is the MOST appropriate initial management strategy?

A. Endoscopic evaluation with possible cauterization
B. Initiation of high-dose corticosteroids
C. Administration of intravenous antibiotics
D. Surgical exploration
E. Observation with serial abdominal examinations
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 32-year-old male with Crohn's disease presents with worsening abdominal pain and diarrhea despite being on maintenance infliximab. The provided imaging was obtained. What is the MOST appropriate next step in management?

A. Increase the dose of infliximab
B. Start a course of oral corticosteroids
C. Perform a colonoscopy with biopsy
D. Surgical resection of the affected bowel segment
E. Initiate treatment with metronidazole and ciprofloxacin
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman with a history of intermittent, self-resolving right upper quadrant pain presents for evaluation. She denies fever, chills, or jaundice, and her physical examination is unremarkable. Routine blood tests, including liver function tests and amylase, are within normal limits. An abdominal ultrasound was performed, and a representative image is shown. Based on the findings in this image and her clinical presentation, what is the most appropriate next step in management?

A. Laparoscopic cholecystectomy alone
B. Prescribe oral analgesics and advise dietary modification
C. Elective endoscopic retrograde cholangiopancreatography (ERCP) for stone extraction
D. Referral for urgent surgical common bile duct exploration
E. Observation with regular clinical review
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 45-year-old male with Crohn's presents with persistent right lower quadrant pain. Stool studies are negative. Review the imaging. What is the MOST likely complication?

A. Toxic megacolon
B. Fistula formation
C. Appendicitis
D. Small bowel obstruction
E. Perforation
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old male presents with increasing dyspnea. He has a history of GORD. The provided image was taken. What is the most appropriate next step?

A. Refer for surgical consultation for fundoplication.
B. Prescribe prokinetic agents to improve gastric emptying.
C. Initiate a trial of PPI therapy and lifestyle modifications.
D. Order a barium swallow study to further evaluate the anatomy.
E. Perform an upper endoscopy to assess for complications.
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Pyloric stenosis as seen on ultrasound in a 6 week old
Image by Dr Laughlin Dawes CC BY-SA 4.0 · Source

A 6-week-old male presents with projectile vomiting after feeds. He is otherwise well-appearing, with normal vital signs and no abdominal distension. An ultrasound was performed, and an image is shown. What is the MOST appropriate next step in management?

A. Barium swallow study
B. Upper endoscopy with biopsy
C. Surgical consultation for pyloromyotomy
D. Initiate erythromycin therapy
E. Trial of thickened feeds
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 62-year-old male with a history of hepatitis C presents with new onset ascites and right upper quadrant pain. His AFP is markedly elevated. A contrast-enhanced ultrasound is performed, as shown. What is the MOST appropriate next step in management?

A. Order a CT scan of the abdomen with IV contrast
B. Referral for liver transplant evaluation
C. Initiate systemic chemotherapy
D. Begin palliative care
E. Perform a percutaneous liver biopsy
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 58-year-old male with known alcoholic cirrhosis undergoes surveillance. AFP is 600 ng/mL. The provided image was obtained. What is the next step?

A. Administer systemic chemotherapy
B. Initiate sorafenib
C. Repeat AFP in 3 months
D. Liver biopsy
E. Refer for liver transplant evaluation
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An ultrasound showing target sign which is a characteristic finding for intussusception on ultrasound, this ultrasound is for a 3 year old boy with intestinal intussusception.
Image by Frank Gaillard CC BY-SA 3.0 · Source

A 3-year-old boy presents with intermittent abdominal pain and vomiting. Stool examination reveals a positive occult blood test. An ultrasound is performed, as shown. What is the MOST appropriate next step in management?

A. Air enema
B. Appendectomy
C. Laparotomy
D. Stool culture
E. IV antibiotics
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 65-year-old male with new onset ascites and elevated ALP has the imaging shown. What is the MOST likely primary malignancy?

A. Colorectal
B. Cholangiocarcinoma
C. Gastric
D. Hepatocellular
E. Pancreatic
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for a routine health check. She reports intermittent episodes of colicky abdominal pain over the past year, which have since resolved. An abdominal ultrasound was performed, the image of which is shown. Liver function tests are within normal limits. Which of the following is the MOST appropriate next step in management?

A. Repeat ultrasound in 6 months
B. Prescribe ursodeoxycholic acid
C. Referral for elective cholecystectomy
D. Order a HIDA scan
E. Initiate a low-fat diet and monitor symptoms
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 35-year-old male with a history of multiple cutaneous vascular lesions presents with recurrent episodes of crampy abdominal pain and melena over the past month. His vital signs are stable. An abdominal CT scan is performed. Considering the clinical presentation and the findings demonstrated in the provided image, what is the most appropriate next step in the management of this patient?

A. Obtain an urgent abdominal MRI for better soft tissue detail
B. Surgical consultation for potential exploration
C. Conservative management with IV fluids and observation
D. Urgent colonoscopy to assess the bowel lumen
E. Attempt hydrostatic reduction with barium enema
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for a routine health check. She reports intermittent episodes of colicky abdominal pain over the past year, which have resolved spontaneously. She denies any current pain, jaundice, fever, or changes in bowel habits. Her physical examination is unremarkable, with a soft, non-tender abdomen. Liver function tests are within normal limits. An abdominal ultrasound, as shown, was performed. Given the clinical context and the ultrasound findings, what is the MOST appropriate next step in management?

A. Recommend a high-fibre diet and analgesics as needed
B. Referral for endoscopic retrograde cholangiopancreatography (ERCP)
C. Schedule a repeat ultrasound in 6 months
D. Prescribe ursodeoxycholic acid and monitor liver function tests
E. Order a hepatobiliary iminodiacetic acid (HIDA) scan
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 70-year-old male with ascending cholangitis undergoes ERCP. The image is obtained. What is the MOST appropriate next step in management?

A. Ursodeoxycholic acid administration
B. Sphincterotomy and stone extraction
C. Observation with serial LFTs
D. Percutaneous transhepatic biliary drainage
E. Cholecystectomy
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 62-year-old male with a history of hepatitis C presents with new onset ascites and right upper quadrant pain. His AFP is markedly elevated. A contrast-enhanced ultrasound is performed, as shown. What is the MOST appropriate next step in management?

A. Surveillance with serial AFP measurements and ultrasound
B. Referral for liver transplant evaluation
C. Percutaneous ethanol ablation
D. Surgical resection
E. Initiation of systemic chemotherapy
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 68-year-old male presents to his general practitioner with a three-month history of progressive dysphagia to both solids and liquids, accompanied by postprandial regurgitation. He also reports experiencing early satiety and occasional episodes of nocturnal coughing. His past medical history is significant for well-controlled hypertension and a remote history of smoking (quit 20 years ago). Physical examination reveals mild epigastric fullness, but is otherwise unremarkable. His vital signs are within normal limits. An abdominal CT scan with contrast was performed, and a representative image is shown. Given the clinical presentation and the findings on the image, which of the following is the MOST appropriate next step in the management of this patient?

A. Referral to a gastroenterologist for surgical evaluation
B. Esophageal manometry to evaluate esophageal motility
C. Empiric treatment with antibiotics for possible aspiration pneumonia
D. Initiation of a proton pump inhibitor and lifestyle modifications
E. Barium swallow study to further delineate the anatomy
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 58-year-old male with cirrhosis secondary to alcohol abuse presents for routine surveillance. His AFP is 25 ng/mL. A contrast-enhanced ultrasound is performed, as shown. What is the MOST appropriate next step in management?

A. MRI of the abdomen with contrast
B. Repeat AFP in 3 months
C. CT of the abdomen with contrast
D. Liver biopsy
E. Initiate sorafenib
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A 35-year-old man presents with 3 weeks of anal pain after defecation, blood on wiping, and constipation (firm stool every 2-3 days). What is the likely diagnosis?

A. Perianal abscess
B. Anal skin tags.
C. Anal fissure
D. Fistula-in-ano
E. Haemorrhoids
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old woman presents with 24 hours of severe right upper quadrant pain, fever, and nausea. Examination reveals RUQ tenderness and a positive Murphy's sign. Vitals: T 38.5°C, HR 105, BP 130/80, RR 18, SpO2 98% RA. Labs: WCC 16, CRP 120, LFTs normal. An urgent abdominal CT is performed. Considering the clinical presentation and the findings on the provided imaging, what is the most appropriate definitive management strategy for this patient?

A. Percutaneous cholecystostomy tube placement.
B. Urgent endoscopic retrograde cholangiopancreatography (ERCP).
C. Intravenous antibiotics and delayed laparoscopic cholecystectomy in 6-8 weeks.
D. Laparoscopic cholecystectomy within 72 hours.
E. Oral antibiotics and analgesia with outpatient surgical referral.
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 62-year-old male presents with jaundice and right upper quadrant pain. Initial labs show elevated bilirubin and alkaline phosphatase. An ERCP is performed, and the image is obtained. What is the MOST appropriate next step in management?

A. Percutaneous transhepatic biliary drainage
B. Cholecystectomy
C. Sphincterotomy and stone extraction
D. Observation with serial liver function tests
E. Ursodeoxycholic acid administration
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents with increasing postprandial fullness and epigastric discomfort. He reports occasional regurgitation of undigested food. A CT scan of the abdomen is performed. Based on the image, what is the MOST appropriate next step in management?

A. H. pylori testing and eradication if positive
B. Surgical repair
C. Trial of proton pump inhibitors
D. Endoscopic surveillance
E. Dietary modification and lifestyle advice
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 70-year-old presents with iron deficiency anaemia and intermittent rectal bleeding. Colonoscopy was performed, and a representative image is shown. Biopsies are pending but malignancy is strongly suspected based on the endoscopic appearance. What is the MOST appropriate next investigation to guide definitive management?

A. Referral for palliative care
B. PET scan
C. Repeat colonoscopy in 3 months
D. CT scan of chest, abdomen, and pelvis
E. Endoscopic ultrasound
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old male presents with fever, jaundice, and right upper quadrant pain. Investigations confirm acute cholangitis secondary to choledocholithiasis. He is taken for urgent ERCP. Following successful cannulation of the common bile duct and injection of contrast, the image is captured. Considering the findings visualised in the image, which of the following interventions is the most appropriate immediate next step to enable successful management of the underlying pathology during this procedure?

A. Attempt stone extraction using a balloon catheter
B. Place a temporary biliary stent
C. Perform an endoscopic sphincterotomy
D. Attempt stone extraction using a Dormia basket
E. Abandon the ERCP and proceed to surgical exploration
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old presents with a 3-day history of fever, jaundice, and severe RUQ pain radiating to the back. Vitals: T 38.5°C, BP 110/70, HR 95. LFTs show bilirubin 150, ALP 450, ALT 120. An ERCP is performed for stone extraction. The image is captured during the procedure after cannulation. Considering the findings demonstrated in the image, what is the most appropriate immediate next step in management during the current procedure?

A. Attempt balloon dilation of the distal duct without sphincterotomy
B. Place a biliary stent and schedule follow-up ERCP
C. Perform endoscopic sphincterotomy
D. Attempt stone fragmentation with lithotripsy before sphincterotomy
E. Abandon the procedure and refer for surgical exploration
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 62-year-old male presents with a 3-month history of worsening upper abdominal pain, significant fatigue, and a 10 kg unintentional weight loss. His medical history includes long-standing peptic ulcer disease managed with proton pump inhibitors. On examination, he has mild hepatomegaly and trace ascites. Initial blood tests show elevated alkaline phosphatase and gamma-glutamyl transferase, with normal serum bilirubin and transaminases. A contrast-enhanced CT scan of the abdomen and pelvis is performed, and representative images are provided. Considering the clinical presentation and the findings demonstrated on the imaging, which of the following represents the MOST appropriate immediate next step in the management of this patient?

A. Commencement of empirical systemic chemotherapy
B. Urgent upper endoscopy with gastric biopsies
C. Immediate referral to palliative care services
D. Image-guided biopsy of a liver lesion
E. Referral for surgical assessment for liver metastasectomy
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 68-year-old male presents with fatigue, weight loss, and vague abdominal discomfort. His past medical history includes a recent diagnosis of gastric mixed adenoneuroendocrine carcinoma (MANEC). A CT scan of the abdomen is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. Surgical resection of the affected liver segments
B. Initiation of palliative care and symptom management
C. Percutaneous radiofrequency ablation of liver lesions
D. Observation with serial imaging in three months
E. Referral to medical oncology for systemic chemotherapy
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 62-year-old male with a history of hepatitis C presents with new onset jaundice and abdominal distension. Ascites is confirmed on examination. The patient denies alcohol use. An ultrasound with contrast is performed, as shown. What is the MOST appropriate next step in management?

A. Referral for liver transplant evaluation
B. Order a triple-phase CT scan of the abdomen
C. Initiate empiric antibiotic therapy for spontaneous bacterial peritonitis
D. Administer intravenous albumin and diuretics
E. Paracentesis for diagnostic and therapeutic purposes
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 55-year-old man with a history of renal transplant on long-term immunosuppressive therapy presents with a 3-month history of intermittent right upper quadrant pain and unintentional weight loss. He denies fever or chills. Physical examination is unremarkable. Liver function tests show mild elevation of alkaline phosphatase and gamma-GT. Inflammatory markers (CRP, ESR) are slightly elevated. Imaging is performed. Considering the clinical context and the findings on imaging, what is the most appropriate next diagnostic step?

A. Schedule a PET scan to assess metabolic activity
B. Perform an MRI of the abdomen for further characterisation
C. Order serological tests for Echinococcus and fungal markers
D. Ultrasound-guided aspiration or biopsy of the lesion for microscopy, culture, and histology
E. Initiate empirical broad-spectrum intravenous antibiotics
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 58-year-old male presents with acute onset LLQ pain, low-grade fever, and mild nausea. His vitals are stable. An abdominal CT scan was performed, the axial view is shown. What is the MOST appropriate initial management strategy?

A. Colonoscopy to rule out malignancy
B. IV antibiotics and hospital admission
C. Stool culture and symptomatic treatment
D. Surgical consultation for possible resection
E. Oral antibiotics and outpatient management
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 62-year-old male with a history of hepatitis C presents with new onset ascites and right upper quadrant pain. His AFP is elevated. A CT scan of the abdomen with and without contrast is performed, as shown. What is the MOST appropriate next step in management?

A. Start sorafenib therapy
B. Referral for liver transplant evaluation
C. Initiate systemic chemotherapy
D. Perform a percutaneous liver biopsy
E. Order a triple phase MRI of the liver
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A 32-year-old male presents to his general practitioner complaining of severe anal pain, especially during and after bowel movements. He also reports seeing bright red blood on the toilet paper. On examination, there is a visible tear in the anal mucosa at the 6 o'clock position. Which of the following is the MOST appropriate initial management strategy?

A. Stool softeners, topical analgesics, and sitz baths
B. Incision and drainage
C. High-fibre diet alone
D. Lateral internal sphincterotomy
E. Rubber band ligation
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A 32-year-old woman presents to her general practitioner complaining of severe anal pain during and after bowel movements, along with bright red blood on the toilet paper. She reports constipation and straining during defecation. Examination reveals a visible longitudinal tear in the anal mucosa at the 6 o'clock position. Which of the following is the MOST appropriate initial management strategy, according to Australian guidelines?

A. Recommend regular sitz baths with antiseptic solution.
B. Prescribe oral antibiotics to treat potential infection.
C. Advise increased fluid and fibre intake, stool softeners, and topical application of a local anaesthetic and a topical nitrate ointment.
D. Refer for surgical lateral internal sphincterotomy.
E. Order a colonoscopy to rule out inflammatory bowel disease.
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 68-year-old patient presents with chronic intermittent upper abdominal discomfort, postprandial fullness, and occasional regurgitation. Physical examination is unremarkable. A chest radiograph is performed as part of the workup. Considering the radiographic findings in the context of the patient's presentation, what is the most appropriate next step in management?

A. Initiate a trial of high-dose proton pump inhibitor therapy.
B. Advise dietary modifications and schedule follow-up in 3 months.
C. Referral for upper gastrointestinal endoscopy.
D. Arrange urgent surgical consultation for repair.
E. Request a barium swallow study to assess anatomy.
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents with abdominal distension, vomiting, and inability to pass flatus for 48 hours. He has a history of prior bowel resection. Examination reveals a tympanitic abdomen and tenderness to palpation. His vitals are stable. An abdominal X-ray is performed, as shown. Considering the clinical context and the radiographic findings, what is the MOST likely underlying cause of this presentation?

A. Post-surgical adhesions
B. Inflammatory bowel disease stricture
C. Volvulus
D. Hernia
E. Malignancy
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old woman presents with a 2-day history of worsening right upper quadrant pain radiating to her back, associated with nausea and a low-grade fever. On examination, she is jaundiced and has tenderness in the right upper quadrant. Laboratory tests show a total bilirubin of 75 µmol/L, ALP 350 U/L, ALT 200 U/L, and WCC 13.5 x 10^9/L. An urgent ERCP is performed, during which the image is captured. Following successful endoscopic clearance and clinical improvement, which of the following is the MOST appropriate long-term management strategy?

A. Long-term treatment with ursodeoxycholic acid
B. Repeat ERCP with cholangiogram in 3 months
C. Regular monitoring of liver function tests every 6 months
D. Strict adherence to a low-fat diet
E. Elective laparoscopic cholecystectomy
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A 33-year-old lady has an HNPCC gene mutation and two sisters with bowel cancer. She reports no change in bowel habits. What is the best surveillance for bowel cancer in this patient?

A. Annual or biennial colonoscopy starting now; discuss aspirin.
B. Colonoscopy at age 40, then every 5 years.
C. Annual iFOBT starting now.
D. Refer to a bowel cancer specialist.
E. Immediate colonoscopy, 5-year repeat, 2-year iFOBT, aspirin at 50.
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old male presents to his GP complaining of a change in bowel habit over the past 6 months. He reports increasing constipation alternating with episodes of diarrhea. He also mentions unintentional weight loss of approximately 5 kg during this period. He denies any family history of bowel cancer. A colonoscopy was performed, and a representative image is shown. Assuming the lesion is confirmed as malignant, what is the MOST appropriate next step in the management of this patient?

A. Referral for palliative care
B. Repeat colonoscopy in 3 years
C. CT scan of the chest, abdomen, and pelvis
D. Initiate adjuvant chemotherapy with FOLFOX
E. Administer a course of broad-spectrum antibiotics
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents with abdominal distension, vomiting, and inability to pass flatus for 48 hours. He has a history of prior bowel resection. Examination reveals a tympanitic abdomen and tenderness to palpation. His vitals are stable. An abdominal X-ray is performed, as shown. Considering the clinical context and the radiographic findings, what is the primary purpose of inserting a nasogastric tube in this patient?

A. Obtaining a sample of gastric contents for analysis.
B. Administering oral contrast for further imaging.
C. Decompressing the dilated bowel loops and reducing vomiting.
D. Providing nutritional support to the patient.
E. Facilitating the passage of flatus.
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 62-year-old male presents with rectal bleeding and altered bowel habits. Colonoscopy findings are shown. What is the MOST appropriate next step?

A. Repeat colonoscopy in 1 year
B. Prescribe high-fiber diet
C. Surgical resection
D. Initiate chemotherapy
E. Administer antibiotics
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with subjective fever and chills. He denies nausea, vomiting, or change in bowel habits. On examination, he is afebrile, heart rate 85 bpm, blood pressure 130/80 mmHg. Abdominal examination reveals tenderness in the left iliac fossa without guarding or rebound. White cell count is 14 x 10^9/L, CRP 80 mg/L. A CT scan of the abdomen and pelvis is performed, the relevant axial image is shown. Considering the patient's presentation and the findings on the provided image, which of the following represents the most appropriate initial management strategy?

A. Discharge with only analgesia and advice to return if symptoms worsen
B. Urgent colonoscopy to assess the affected segment
C. Urgent surgical consultation for potential colectomy
D. Immediate inpatient admission for intravenous antibiotics
E. Outpatient management with oral antibiotics and analgesia
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A 45-year-old man presents to the emergency department with severe epigastric pain radiating to his back, which started suddenly a few hours ago. He has a history of alcohol use disorder and has been drinking heavily over the past week. On examination, he is diaphoretic and in distress. His vital signs show a blood pressure of 100/60 mmHg, heart rate of 110 bpm, respiratory rate of 22 breaths per minute, and temperature of 37.8°C. Laboratory tests reveal elevated serum lipase and amylase levels. An abdominal ultrasound shows no gallstones. Which of the following is the most appropriate initial management step for this patient?

A. Nasogastric tube insertion
B. Intravenous fluid resuscitation
C. Initiation of broad-spectrum antibiotics
D. Immediate surgical consultation
E. Oral rehydration therapy
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 68-year-old male presents with fatigue, weight loss, and vague abdominal discomfort. His past medical history is significant for a recently diagnosed gastric mixed adenoneuroendocrine carcinoma (MANEC). A CT scan of the abdomen is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. Observation with serial imaging
B. Palliative chemotherapy
C. Liver transplantation
D. Radiofrequency ablation of liver lesions
E. Surgical resection of the primary tumor
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 65-year-old male with chronic hepatitis C cirrhosis undergoes routine surveillance imaging. He has no new symptoms. Liver function tests are stable. Alpha-fetoprotein is mildly elevated. The provided images are obtained. What is the most appropriate next step in management?

A. Referral for liver transplant assessment
B. Percutaneous biopsy of the lesion
C. Initiation of systemic therapy
D. Transarterial chemoembolisation
E. Repeat imaging in 3 months
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 62-year-old male with a history of hepatitis C presents with new-onset right upper quadrant pain and a 5kg weight loss over the past 3 months. His liver function tests show elevated ALT and AST. An abdominal CT scan with and without contrast is performed (image attached). What is the MOST appropriate next step in management?

A. Order serum alpha-fetoprotein (AFP) levels and monitor for elevation
B. Recommend lifestyle modifications, including alcohol cessation and weight loss
C. Referral to hepatology for consideration of liver biopsy and further management
D. Initiate empiric antibiotic therapy for suspected cholangitis
E. Schedule a follow-up ultrasound in 3 months to monitor the lesion
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old male presents with acute LLQ pain. The provided image was obtained. What dietary advice is most appropriate upon resolution of acute symptoms?

A. Low-residue diet
B. Gluten-free diet
C. Lactose-free diet
D. Elemental diet
E. High-fibre diet
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 62-year-old woman presents with right upper quadrant pain, fever, and jaundice. Initial labs show elevated bilirubin and alkaline phosphatase. An ERCP is performed, and the image is obtained. What is the MOST appropriate next step in management?

A. Ursodeoxycholic acid administration
B. Cholecystectomy
C. Observation with serial liver function tests
D. Sphincterotomy and stone extraction
E. Percutaneous transhepatic biliary drainage
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old man presents to his GP with a 4-month history of increasing constipation alternating with loose stools, occasional rectal bleeding, and a feeling of incomplete evacuation. He reports fatigue but denies significant weight loss. His physical examination, including digital rectal examination, is normal. Full blood count shows a haemoglobin of 115 g/L with low ferritin. A colonoscopy is performed, and the image provided is a representative view from the procedure. Considering the clinical presentation and the finding observed during the colonoscopy, what is the most appropriate immediate next step in the management of this patient?

A. Obtain biopsies from the lesion for histological assessment and arrange for staging investigations.
B. Schedule a repeat colonoscopy in 6 months to assess for changes in the appearance of the lesion.
C. Prescribe a course of oral corticosteroids for presumed inflammatory bowel disease.
D. Recommend dietary modification and bulk-forming laxatives to manage the change in bowel habit.
E. Refer the patient directly for urgent surgical consultation and resection planning.
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 68-year-old male with a history of GERD presents with worsening dysphagia and nocturnal cough. An X-ray is performed. Which of the following is the MOST likely underlying mechanism contributing to the patient's dysphagia?

A. Inflammation of the esophageal mucosa
B. Gastric acid hypersecretion
C. Esophageal dysmotility secondary to vagal nerve damage
D. Mechanical obstruction due to esophageal compression
E. Decreased lower esophageal sphincter tone
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 68-year-old male presents with fatigue, weight loss, and vague abdominal discomfort. His past medical history includes a recent diagnosis of gastric mixed adenoneuroendocrine carcinoma (MANEC). A CT scan of the abdomen is performed, as shown. Which of the following is the MOST appropriate next step in management?

A. Initiation of immunotherapy
B. Palliative chemotherapy
C. Observation with serial imaging
D. Transarterial chemoembolization (TACE)
E. Surgical resection of the liver lesions
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