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fever

Practice targeted AMC-style multiple-choice questions on fever.

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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old female presents to the emergency department with a 24-hour history of severe right upper quadrant pain radiating to her back, associated with nausea, vomiting, and subjective fever. On examination, she is febrile (38.5°C) and has marked tenderness and guarding in the right upper quadrant. Her vital signs are otherwise stable. Blood tests reveal a white cell count of 15 x 10^9/L and C-reactive protein of 120 mg/L. Liver function tests, including bilirubin, are within normal limits. She is initiated on intravenous fluids and broad-spectrum antibiotics. Imaging is subsequently performed. Considering the patient's clinical presentation and the findings demonstrated in the provided imaging, what is the most appropriate definitive management strategy?

A. Endoscopic retrograde cholangiopancreatography (ERCP)
B. Delayed laparoscopic cholecystectomy in 6-8 weeks
C. Percutaneous cholecystostomy tube insertion
D. Early laparoscopic cholecystectomy within 72 hours
E. Continue conservative management with IV antibiotics and analgesia only
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A 32-year-old woman presents to the emergency department with a 2-day history of fever, chills, and right flank pain. She has a history of recurrent urinary tract infections. On examination, she is febrile with a temperature of 38.5°C, her heart rate is 110 bpm, and her blood pressure is 110/70 mmHg. There is tenderness on palpation of the right costovertebral angle. Urinalysis shows pyuria and bacteriuria. What is the most appropriate initial management for this patient?

A. Intravenous fluids only
B. Observation and repeat urinalysis
C. Pain management with NSAIDs
D. Intravenous antibiotics
E. Oral antibiotics
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 62-year-old male with a history of poorly controlled diabetes presents with fever, RUQ pain, and night sweats for 3 weeks. Initial blood cultures are negative. Imaging is performed, as shown. What is the MOST appropriate next step in management?

A. Albendazole therapy
B. Percutaneous drainage and culture of the lesion
C. Surgical resection of the affected liver segment
D. Empiric broad-spectrum antibiotics
E. Observation with serial imaging
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A 40-year-old man presents with fever, pleuritic chest pain, and cough. A chest X-ray shows a pleural effusion. What is the next step in management?

A. Start steroids.
B. Perform a thoracentesis.
C. Start antibiotics.
D. Observe and repeat imaging in 2 weeks.
E. Order a CT scan.
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A 32-year-old woman presents to the emergency department with a 2-day history of fever, malaise, and a painful, swollen left knee. She denies any recent trauma or travel history. She has no significant past medical history and is not on any medications. On examination, her temperature is 38.7°C, heart rate is 110 bpm, and blood pressure is 120/80 mmHg. The left knee is erythematous, warm, and tender with a moderate effusion, and she has limited range of motion due to pain. Laboratory tests reveal leukocytosis with a left shift. Blood cultures are pending. What is the most appropriate next step in the management of this patient?

A. Start empirical intravenous antibiotics
B. Arthrocentesis of the left knee
C. Administer oral NSAIDs
D. Refer to rheumatology for further evaluation
E. Order an MRI of the knee
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A 25-year-old man presents to the emergency department with a 2-day history of severe headache, photophobia, and neck stiffness. He has no significant past medical history and is not on any medications. On examination, he is febrile with a temperature of 39°C, and there is a positive Brudzinski's sign. What is the most appropriate initial investigation to confirm the diagnosis?

A. Blood cultures
B. Electroencephalogram (EEG)
C. MRI of the brain
D. Lumbar puncture
E. CT scan of the head
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 62-year-old male with a history of poorly controlled diabetes presents with right upper quadrant pain, fever, and night sweats for 3 weeks. He is on immunosuppressants following a renal transplant 5 years ago. Blood cultures are pending. Imaging is performed, as shown. What is the MOST appropriate next step in management?

A. Empiric antifungal therapy
B. Observation and serial imaging
C. Metronidazole and supportive care
D. Albendazole and surgical resection
E. Percutaneous drainage and antibiotics
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old woman presents with 2 days of worsening right upper quadrant pain radiating to her back, nausea, and subjective fever. On examination, she is tender in the RUQ. Vitals are stable. Labs show WCC 15.0, CRP 120. This image is obtained. Given the clinical context and imaging findings, what is the most appropriate definitive management strategy?

A. Percutaneous cholecystostomy tube insertion
B. Medical management with IV antibiotics and analgesia only
C. Discharge home with oral antibiotics and outpatient follow-up
D. Laparoscopic cholecystectomy within 24-72 hours
E. Urgent ERCP to relieve obstruction
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 45-year-old woman presents with RUQ pain, fever, and nausea. The image shows the likely cause. What is the MOST appropriate next step in management?

A. Observation and oral analgesics
B. IV antibiotics and analgesia
C. HIDA scan
D. ERCP with sphincterotomy
E. Laparoscopic cholecystectomy
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A 55-year-old farmer presents with a week of fever, severe headache, and myalgia. He reports recent exposure to lambing ewes on his property. Physical examination is unremarkable except for mild hepatomegaly and normal vital signs. Considering the patient's occupation, exposure history, and clinical presentation, what is the most likely diagnosis?

A. Q fever
B. Brucellosis
C. Leptospirosis
D. Ross River fever
E. Influenza
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A 65-year-old man undergoes successful coil embolization of a ruptured anterior communicating artery aneurysm. Two days post-procedure, he develops a temperature of 38.1°C, generalized malaise, and a headache unresponsive to paracetamol. Neurological exam is unchanged from baseline. CRP is 45 mg/L (normal <5). Which of the following is the most likely cause of his current symptoms?

A. Bacterial meningitis
B. Post-embolization syndrome
C. Re-rupture of the aneurysm
D. Vasospasm
E. Deep vein thrombosis
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 62-year-old male with a history of poorly controlled diabetes presents with right upper quadrant pain, fever, and night sweats for 3 weeks. He is on immunosuppressants following a renal transplant 5 years ago. Blood cultures are pending. Imaging is performed, as shown. What is the MOST appropriate next step in management?

A. Percutaneous drainage and antibiotics
B. Observation and serial imaging
C. Metronidazole and supportive care
D. Empiric amphotericin B
E. Albendazole and surgical resection
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A 78M presents with cough, fever, confusion. BP 90/60, RR 30, Temp 38.5, SpO2 90% on air. CXR shows LUL consolidation. What is the most appropriate initial management?

A. Arrange urgent viral PCR testing
B. Initiate oral antibiotics and admit to general ward
C. Discharge home with oral antibiotics
D. Perform urgent bronchoscopy
E. Initiate IV antibiotics and assess for ICU admission
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A 55-year-old farmer presents with a week of high fever, severe retro-orbital headache, and profound muscle aches. He denies cough, sore throat, or rash. On examination, temperature is 39.5°C, pulse 90, BP 120/80. Lungs are clear to auscultation. Abdomen is soft, non-tender. Initial bloods show mildly elevated transaminases. What is the most likely diagnosis?

A. Typhoid fever
B. Leptospirosis
C. Influenza
D. Dengue fever
E. Q fever
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Based on the clinical presentation and the provided image, what is the most appropriate setting for this patient's initial management?

A. Inpatient admission for intravenous antibiotics and observation.
B. Outpatient management with oral antibiotics and analgesia.
C. Admission for bowel rest and total parenteral nutrition.
D. Urgent surgical consultation for potential intervention.
E. Discharge home with only analgesia and dietary advice.
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old woman presents to the emergency department with right upper quadrant abdominal pain, fever, and jaundice. Her vital signs are: temperature 38.5°C, heart rate 110 bpm, blood pressure 110/70 mmHg, respiratory rate 20 breaths per minute, and oxygen saturation 97% on room air. Initial laboratory investigations reveal: white blood cell count 14,000/µL, total bilirubin 6.0 mg/dL, alkaline phosphatase 450 U/L, ALT 300 U/L, and AST 250 U/L. An ERCP is performed, and the image is obtained. Following successful intervention, what is the MOST appropriate next step in managing this patient's condition?

A. Continue intravenous antibiotics and perform a percutaneous cholecystostomy tube placement.
B. Observe the patient without antibiotics and schedule an outpatient laparoscopic cholecystectomy in 6-8 weeks.
C. Administer intravenous antibiotics and schedule a laparoscopic cholecystectomy during the same admission.
D. Discharge the patient home with oral antibiotics and schedule an outpatient laparoscopic cholecystectomy.
E. Perform an open cholecystectomy during the same admission.
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A 10-year-old presents with a sore throat, fever, and tonsillar exudates. Rapid strep test is negative. What is the MOST appropriate next step?

A. Throat culture
B. Azithromycin
C. Observe and provide symptomatic treatment
D. Monospot test
E. Amoxicillin
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 28-year-old female, recently emigrated from Southeast Asia, presents to her general practitioner with complaints of fatigue, a persistent low-grade fever (37.8°C), and a non-productive cough that has been present for approximately one month. She denies any significant past medical history and is not currently taking any medications. Physical examination reveals slightly diminished breath sounds in the upper right lobe, but is otherwise unremarkable. Initial blood work, including a complete blood count and comprehensive metabolic panel, are within normal limits. A chest X-ray revealed a suspicious lesion in the right upper lobe, prompting a PET-CT scan, an axial slice of which is shown. Given the patient's history, clinical presentation, and the findings on the PET-CT scan, which of the following is the MOST appropriate next step in the diagnostic workup?

A. Prescribe a course of broad-spectrum antibiotics to cover community-acquired pneumonia.
B. Order a CT-guided needle biopsy of the lesion.
C. Start empiric treatment with isoniazid, rifampicin, pyrazinamide, and ethambutol (HRZE).
D. Refer the patient to a pulmonologist for bronchoscopy with bronchoalveolar lavage.
E. Initiate sputum acid-fast bacilli (AFB) smears and cultures.
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old man with a history of cholelithiasis presents with a 2-day history of fever, jaundice, and severe right upper quadrant pain. His vital signs are stable, but laboratory tests show elevated bilirubin and alkaline phosphatase. He is undergoing urgent ERCP for management of suspected choledocholithiasis and cholangitis. Following successful cannulation and injection of contrast, the image is obtained. Considering the findings demonstrated in the image in the context of this patient's presentation, what is the most appropriate immediate next step during this procedure?

A. Placement of a biliary stent
B. Mechanical lithotripsy
C. Balloon dilation of the common bile duct
D. Endoscopic sphincterotomy
E. Attempt stone extraction with a basket
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents with a 2-day history of worsening left lower quadrant abdominal pain, fever (38.5°C), and nausea. He has a history of similar, milder pain episodes. Examination reveals left iliac fossa tenderness with guarding. Bloods show WCC 16, CRP 120. A CT scan is performed (image provided). Considering the clinical picture and the imaging findings, which of the following represents the most appropriate initial management strategy?

A. Administer intravenous fluids and analgesia, and observe in the emergency department for 12 hours.
B. Initiate intravenous broad-spectrum antibiotics and admit for inpatient care.
C. Arrange urgent surgical review for consideration of immediate operative intervention.
D. Prescribe oral antibiotics and arrange follow-up with his general practitioner.
E. Schedule an urgent colonoscopy to evaluate the severity and rule out malignancy.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents with LLQ pain and fever. The provided image was obtained. What is the most appropriate initial management?

A. Surgical consultation for possible resection
B. Oral antibiotics and outpatient follow-up
C. Colonoscopy to rule out malignancy
D. Stool culture to rule out infectious colitis
E. IV antibiotics and admission for observation
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A 10-year-old presents with a sore throat, fever, and tonsillar exudates. Rapid strep test is negative. What is the most appropriate next step?

A. Throat culture
B. Start antibiotics
C. Refer to ENT
D. Prescribe analgesics and advise on symptomatic treatment
E. Order a monospot test
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 28-year-old immunocompetent patient presents with a chronic cough and low-grade fever. Initial investigations, including sputum microscopy, are negative. A PET-CT scan was performed (image shown). What is the MOST appropriate next step?

A. Bronchoscopy with biopsy
B. Empiric antibiotic therapy
C. Referral for surgical resection
D. Repeat sputum cultures
E. Initiate anti-tuberculosis therapy
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A 62-year-old male presents to the emergency department with a 2-day history of right flank pain, fever, and nausea. He reports a history of recurrent urinary tract infections. On examination, he has right costovertebral angle tenderness. Urinalysis reveals pyuria and leukocyte esterase. Which of the following is the most likely underlying condition related to the organ primarily affected in the right lumbar region?

A. Cholecystitis with referred pain
B. Appendicitis with atypical presentation
C. Musculoskeletal strain
D. Pyelonephritis secondary to ascending urinary tract infection
E. Diverticulitis of the ascending colon
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 45-year-old woman presents to the ED with right upper quadrant pain, fever, and nausea for 24 hours. Her vital signs are: HR 110, BP 130/80, Temp 38.5°C. An abdominal CT scan is performed (image attached). What is the MOST appropriate next step in management?

A. Surgical consultation for cholecystectomy
B. HIDA scan to confirm diagnosis
C. Start intravenous antibiotics and observe
D. ERCP for possible choledocholithiasis
E. Discharge home with oral antibiotics and analgesics
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Considering the clinical presentation and the findings on the provided image, which of the following investigations is most appropriate to recommend for this patient *after* resolution of the acute episode?

A. Colonoscopy in 6-8 weeks
B. Repeat CT scan of the abdomen and pelvis
C. Urgent colonoscopy within 48 hours
D. Faecal occult blood test
E. Barium enema
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 52-year-old female presents with right upper quadrant pain, fever, and leukocytosis. The image shows the likely cause. What is the MOST appropriate initial management?

A. Ursodeoxycholic acid
B. Oral antibiotics and outpatient follow-up
C. IV fluids, analgesia, and surgical consultation
D. Hepatobiliary iminodiacetic acid (HIDA) scan
E. Endoscopic retrograde cholangiopancreatography (ERCP)
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A 56-year-old gentleman, a gardener and cat owner, presents with 24 hours of pain, swelling, and redness on his right index finger. His temperature is 38.1°C and pulse is 72. Suspected gout. What is the most appropriate next step?

A. Aspirate joint for microscopy and culture.
B. Urgent hospital referral for drainage and IV antibiotics.
C. Prescribe oral antibiotics and review in 24 hours.
D. Start diclofenac TDS and discuss allopurinol.
E. Order serum uric acid level.
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A 30-year-old woman presents with fever, hemoptysis, and night sweats. A chest X-ray shows a round lesion with an air-fluid level. What is the most likely diagnosis?

A. Tuberculosis
B. Pulmonary embolism
C. Bronchiectasis
D. Lung cancer
E. Lung abscess
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A 65-year-old man with a history of COPD presents with fever, productive cough, and shortness of breath for 3 days. On examination, he has crackles in the right lower lung field. A chest X-ray shows a right lower lobe consolidation. What is the most likely diagnosis?

A. Tuberculosis
B. Lung cancer
C. Heart failure
D. Pulmonary embolism
E. Community-acquired pneumonia
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 28-year-old with Crohn's presents with new fever and abdominal pain. The patient's CRP is elevated. Review the imaging. What is the MOST appropriate next step?

A. Surgical consultation
B. Initiate a course of corticosteroids
C. Increase current infliximab dose
D. Repeat imaging in 6 weeks
E. Start oral metronidazole and ciprofloxacin
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old presents with 2 days of left lower quadrant pain, fever (38.5°C), and nausea. On examination, there is localised tenderness in the LLQ. Vitals: BP 130/80, HR 90, RR 16, SpO2 98%. CRP is 150 mg/L, WCC 18 x 10^9/L. This image is obtained as part of the workup. Considering the clinical context and the findings on the image, which of the following represents the most appropriate initial management strategy?

A. Colonoscopy to assess the severity
B. Inpatient management with intravenous antibiotics
C. Percutaneous drainage of the collection
D. Urgent surgical consultation for laparotomy
E. Outpatient oral antibiotics and clear fluid diet
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 45-year-old woman presents to the ED with right upper quadrant pain, fever, and nausea for 24 hours. Her vital signs are: HR 110, BP 130/80, Temp 38.5°C. An abdominal CT scan is performed (image attached). What is the MOST appropriate next step in management?

A. Percutaneous gallbladder drainage
B. ERCP for possible choledocholithiasis
C. Start intravenous antibiotics and observe
D. Surgical consultation for cholecystectomy
E. Discharge with oral antibiotics and follow-up
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A 58-year-old man presents to his general practitioner with a 3-week history of intermittent fever, severe headache, and profound fatigue. He describes the headache as diffuse and often retro-orbital, not relieved by simple analgesia. He also reports generalised muscle aches and occasional night sweats. He denies cough, shortness of breath, or gastrointestinal symptoms. His medical history is unremarkable, and he takes no regular medications. He lives on a rural property in Queensland where he raises sheep and cattle. On examination, he is afebrile at the time of consultation (37.2°C), blood pressure is 130/80 mmHg, pulse is 85 bpm, and respiratory rate is 16 breaths per minute. Physical examination is otherwise unremarkable; specifically, there is no rash, lymphadenopathy, or focal neurological signs. Initial laboratory investigations reveal a white cell count of 7.5 x 10^9/L (neutrophils 65%, lymphocytes 25%), haemoglobin 145 g/L, platelets 250 x 10^9/L. Liver function tests show AST 85 U/L (normal <40), ALT 90 U/L (normal <40), alkaline phosphatase 110 U/L (normal <130), total bilirubin 15 µmol/L (normal <20). C-reactive protein is elevated at 45 mg/L (normal <5). A chest X-ray performed a week prior was reported as normal. Given the clinical presentation and epidemiological context, which of the following is the most appropriate initial diagnostic investigation?

A. Viral serology panel (including CMV, EBV, Hepatitis A, B, C)
B. Serology for Coxiella burnetii (phase I and II antibodies)
C. Lumbar puncture for CSF analysis
D. Abdominal ultrasound
E. Blood cultures
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A 28-year-old male with Crohn's disease presents with increased abdominal pain, fever, and bloody stools. He is on azathioprine. What is the most appropriate next step?

A. Prescribe a high-fibre diet.
B. Start a course of oral metronidazole.
C. Increase the dose of azathioprine.
D. Order a CT scan of the abdomen and pelvis.
E. Reassure the patient and schedule a follow-up appointment.
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old male presents with LLQ pain, fever, and increased WBC. A CT scan is performed, as shown. He is hemodynamically stable. What is the MOST appropriate initial management?

A. IV antibiotics and bowel rest
B. High-fiber diet and increased fluid intake
C. Surgical resection
D. Flexible sigmoidoscopy
E. Oral antibiotics and outpatient follow-up
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 60-year-old man, post-chemotherapy, presents with fever and abdominal pain. The images are shown. What is the MOST appropriate initial therapy?

A. Surgical resection
B. Amphotericin B
C. Albendazole
D. Broad-spectrum antibiotics
E. Percutaneous drainage
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents to the ED with left lower quadrant abdominal pain, fever, and nausea for 3 days. His WBC count is 14,000. A CT scan of the abdomen and pelvis is performed, the axial view is shown. What is the most appropriate next step in management?

A. Stool culture to rule out infectious colitis
B. IV antibiotics and bowel rest
C. Surgical resection of the affected bowel segment
D. Oral antibiotics and outpatient follow-up
E. Flexible sigmoidoscopy to rule out malignancy
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A 35-year-old man presents to the clinic with a 3-month history of fatigue, weight loss, and night sweats. He also reports a persistent cough that has recently become productive of blood-streaked sputum. He has no significant past medical history and is not on any medications. He recently returned from a trip to Southeast Asia. On examination, he is febrile and has bilateral crackles in the upper lung fields. A chest X-ray shows cavitary lesions in the upper lobes. What is the most likely diagnosis?

A. Community-acquired pneumonia
B. Chronic obstructive pulmonary disease (COPD)
C. Lung cancer
D. Sarcoidosis
E. Pulmonary tuberculosis
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old male presents with 2 days of constant right upper quadrant pain radiating to the back, associated with nausea and subjective fever. On examination, he is febrile (38.5°C) with significant tenderness and a positive Murphy's sign in the right upper quadrant. His white cell count is elevated at 15 x 10^9/L, and CRP is 120 mg/L. Liver function tests are within normal limits. Considering the clinical presentation and the provided imaging, what is the most appropriate timing for definitive surgical management?

A. Within 72 hours of admission
B. Only if symptoms fail to resolve with antibiotics
C. Following a trial of percutaneous drainage
D. Urgently, within 6 hours
E. After 6-8 weeks of medical management
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents to the ED with left lower quadrant abdominal pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed. Based on the image, what is the most appropriate next step in management?

A. Increase dietary fiber intake
B. Surgical resection of the affected bowel segment
C. Flexible sigmoidoscopy
D. IV antibiotics and bowel rest
E. Stool culture for C. difficile
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old woman presents to the emergency department with right upper quadrant abdominal pain, fever, and jaundice. Her past medical history is significant for hypertension and hyperlipidemia. Initial laboratory investigations reveal elevated bilirubin, alkaline phosphatase, and gamma-glutamyl transferase (GGT) levels. An ultrasound of the abdomen showed dilated intrahepatic ducts, but the common bile duct was difficult to visualize due to overlying bowel gas. An ERCP was performed, and an image obtained during the procedure is shown. Following successful removal of the obstruction, what is the MOST appropriate next step in managing this patient's condition?

A. Prescribe oral ursodeoxycholic acid
B. Schedule a laparoscopic cholecystectomy
C. Administer intravenous antibiotics and monitor liver function tests
D. Perform a percutaneous transhepatic cholangiogram
E. Discharge the patient with instructions for a low-fat diet
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A 32-year-old woman presents to the emergency department with a 2-day history of fever, headache, and a rash that started on her wrists and ankles and has now spread to her trunk. She recently returned from a camping trip in the Northern Territory. On examination, she is febrile at 38.5°C, with a heart rate of 110 bpm and blood pressure of 100/70 mmHg. The rash is maculopapular and blanching. Laboratory tests reveal thrombocytopenia and elevated liver enzymes. Which of the following is the most likely diagnosis?

A. Systemic lupus erythematosus
B. Drug reaction
C. Rickettsial infection
D. Viral exanthem
E. Meningococcal infection
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents to the ED with left lower quadrant abdominal pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. IV antibiotics and bowel rest
B. Surgical resection of the affected bowel segment
C. Flexible sigmoidoscopy to rule out malignancy
D. Increase dietary fiber intake and follow up with GP
E. Stool culture to rule out infectious colitis
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 62-year-old male with a history of poorly controlled diabetes presents with fever, RUQ pain, and recent travel to a rural area. Lab results show elevated ALP and GGT. Imaging is performed. What is the MOST appropriate next step in management?

A. Metronidazole
B. Observation and serial imaging
C. Percutaneous drainage and antibiotics
D. Albendazole and surgical resection
E. Ceftriaxone and doxycycline
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old man presents to the emergency department with a 2-day history of worsening left lower quadrant abdominal pain, associated with fever and chills. He reports a change in bowel habit with increased constipation. On examination, he is febrile at 38.6°C and has significant tenderness and guarding in the left iliac fossa. His white cell count is 18 x 10^9/L. A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's presentation and the findings on the provided image, which of the following represents the most appropriate initial management strategy?

A. Prescribe oral antibiotics and advise outpatient follow-up with his general practitioner.
B. Schedule an urgent colonoscopy to assess the extent of the disease process.
C. Initiate intravenous broad-spectrum antibiotics and arrange hospital admission for monitoring.
D. Provide analgesia and antiemetics, and discharge home with instructions to return if symptoms worsen.
E. Arrange urgent surgical review for consideration of immediate operative intervention.
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A 35-year-old woman who recently underwent laparoscopic appendicectomy and completed a 5-day course of cefotaxime presents with a 3-day history of diarrhea and a temperature of 39.5°C. Her vital signs are otherwise normal, and a digital rectal exam is normal. Examination reveals erythematous port sites. Which of the following is the most likely diagnosis?

A. Clostridium difficile infection
B. Anastomotic leak
C. Pelvic abscess
D. Surgical site infection
E. Intra-abdominal abscess
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old man presents with 3 days of worsening left lower quadrant pain, fever, and nausea. He has a history of diverticulosis. On examination, he is tachycardic (HR 105), afebrile (37.5°C), and has localised tenderness with guarding in the left iliac fossa. His blood tests show a WCC of 16 x 10^9/L and CRP 150 mg/L. He is commenced on intravenous antibiotics. A CT scan is performed (image provided). Considering the clinical context and the findings on the image, what is the most appropriate next step in management?

A. Arrange for percutaneous drainage of the collection.
B. Prepare for urgent surgical resection of the affected bowel segment.
C. Transition to oral antibiotics and discharge home.
D. Request a repeat CT scan in 24 hours to assess for changes.
E. Continue intravenous antibiotics and monitor clinical progress.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with fever (38.2°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His blood pressure is 130/80 mmHg, heart rate 85 bpm, respiratory rate 16 bpm. Blood tests show a white cell count of 14 x 10^9/L and CRP 80 mg/L. A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's presentation and the findings on the provided image, which of the following is the most appropriate initial management strategy?

A. Intravenous antibiotics and hospital admission
B. Urgent surgical consultation for sigmoid colectomy
C. Oral antibiotics and outpatient management
D. Repeat CT scan in 24 hours to assess for progression
E. Immediate colonoscopy to assess the extent of disease
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A 25-year-old woman presents to the clinic with a 2-week history of fatigue, sore throat, and swollen glands. She also reports a low-grade fever and mild headache. On examination, she has cervical lymphadenopathy and mild splenomegaly. A monospot test is positive. What is the most appropriate advice regarding her physical activity?

A. Engage in light exercise to improve symptoms
B. Resume normal activities immediately
C. Start a course of corticosteroids to reduce symptoms
D. Avoid all physical activity for 6 months
E. Avoid contact sports for at least 4 weeks
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