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postmenopausal

Practice targeted AMC-style multiple-choice questions on postmenopausal.

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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 70-year-old woman, post-mastectomy, presents with a chronic, pruritic lesion. What is the MOST likely underlying pathophysiology?

A. Contact dermatitis
B. Intraepithelial adenocarcinoma
C. Granulomatous inflammation
D. Dermal melanocytosis
E. Superficial fungal infection
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A 62-year-old postmenopausal woman presents to her general practitioner with complaints of severe hot flashes that significantly affect her quality of life. She has a history of breast cancer diagnosed three years ago, which was treated with surgery and chemotherapy. Her cancer was estrogen receptor-positive. She is currently on tamoxifen as part of her ongoing treatment. She is concerned about the use of hormone replacement therapy due to her cancer history. What is the most appropriate management option for her hot flashes?

A. Conjugated estrogens
B. Clonidine
C. Paroxetine
D. Black cohosh
E. Gabapentin
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman undergoes routine screening mammography. She is asymptomatic with no relevant family history of breast cancer. Physical examination is unremarkable. The provided image is a detail from her mammogram. Based on the findings demonstrated in the image, what is the most appropriate immediate next step in the management of this patient?

A. Refer directly to a breast surgeon for consultation.
B. Refer for breast MRI for further characterisation.
C. Proceed directly to core needle biopsy of the suspicious area.
D. Perform additional diagnostic mammographic views and potentially targeted ultrasound.
E. Schedule for routine annual screening mammography in 12 months.
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A 50-year-old woman presents with a newly discovered, firm, mobile lump in her left breast, approximately 2 cm in size. She has no family history of breast cancer. She is post-menopausal. On examination, the lump is palpable in the upper outer quadrant, appears well-defined, and is non-tender. There are no skin changes or nipple discharge. Axillary nodes are not palpable. Considering the Australian guidelines for breast lump assessment, which of the following is the most appropriate initial investigation?

A. Mammography and ultrasound
B. Clinical breast examination and review in 3 months
C. Ultrasound and core biopsy
D. Fine needle aspiration cytology
E. Mammography alone
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