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asthma

Practice targeted AMC-style multiple-choice questions on asthma.

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A 48-year-old woman presents to her GP with a 3-month history of increasing fatigue, exertional dyspnoea, and a persistent cough productive of small amounts of mucus. She mentions a history of recurrent 'sinus infections' over the past year, often treated with antibiotics. She has recently felt lightheaded on standing. On examination, her blood pressure is 95/60 mmHg, pulse 88 bpm, respiratory rate 20 breaths/min, and oxygen saturation 96% on room air. Chest auscultation reveals diffuse expiratory wheezes. Blood tests performed last week show haemoglobin 85 g/L (reference range 120-150), MCV 72 fL (reference range 80-100), and normal white cell count and platelet count. Spirometry performed concurrently shows an FEV1/FVC ratio of 0.65 (predicted >0.70) with partial reversibility after bronchodilator. Considering the clinical presentation and investigations, what is the most appropriate next step in management?

A. Order ANCA testing.
B. Initiate iron supplementation and investigate for gastrointestinal blood loss.
C. Arrange a high-resolution CT scan of the chest and sinuses.
D. Refer for urgent bronchoscopy.
E. Prescribe a course of oral corticosteroids and review in one week.
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A 7-year-old boy with a history of asthma presents to the clinic with increased wheezing and shortness of breath over the past week. He has been using his salbutamol inhaler more frequently, but his symptoms persist. His mother reports that he has been waking up at night due to coughing. What is the most appropriate next step in managing this child's asthma?

A. Prescribe an oral corticosteroid
B. Add a long-acting beta-agonist
C. Start an inhaled corticosteroid
D. Refer to a pulmonologist
E. Increase the dose of salbutamol
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A 7-year-old boy is brought to the emergency department by his parents due to sudden onset wheezing and difficulty breathing. He has a history of asthma, for which he uses a salbutamol inhaler as needed. His parents report that he had a cold over the past few days, and today he started wheezing and became short of breath. On examination, he is in moderate respiratory distress, with a respiratory rate of 30 breaths per minute, oxygen saturation of 92% on room air, and widespread wheezing on auscultation. What is the most appropriate initial management step for this child?

A. Administer nebulized salbutamol
B. Provide supplemental oxygen
C. Initiate inhaled corticosteroids
D. Start oral corticosteroids
E. Administer intravenous magnesium sulfate
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A 10-year-old boy presents to his GP with a chronic, intensely itchy rash affecting the flexural areas of his elbows and knees, as well as his neck. His parents report that he has had this condition on and off since infancy, with periods of remission and exacerbation. He also has a history of allergic rhinitis and asthma. On examination, the skin in the affected areas is dry, lichenified, and excoriated. There are also scattered papules and plaques. The patient reports significant sleep disturbance due to the itch. Topical corticosteroids have provided temporary relief in the past, but the rash flares up again soon after stopping treatment. Which of the following is the MOST appropriate next step in managing this patient's atopic dermatitis?

A. Refer the patient to a dermatologist for systemic immunosuppressant therapy without attempting further topical treatments.
B. Initiate treatment with a topical calcineurin inhibitor such as tacrolimus or pimecrolimus.
C. Recommend oral antihistamines as the sole treatment for the itch.
D. Advise strict avoidance of all potential allergens based on unproven allergy testing.
E. Prescribe a potent topical corticosteroid for long-term daily use.
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A 3-year-old child presents to the clinic with a history of recurrent wheezing episodes, especially during viral infections. What is the most common cause of wheezing in children under 5 years of age?

A. Asthma
B. Foreign body aspiration
C. Viral bronchiolitis
D. Congenital heart disease
E. Cystic fibrosis
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A 4-year-old child presents with a history of recurrent wheezing and cough, particularly at night and with exercise. What is the most appropriate long-term management strategy?

A. Antibiotics
B. Short-acting beta-agonists as needed
C. Oral corticosteroids
D. Inhaled corticosteroids
E. Leukotriene receptor antagonists
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A 45-year-old woman presents to her general practitioner with a 3-month history of persistent cough and occasional wheezing. She has a history of asthma, which has been well-controlled with inhaled corticosteroids. She denies any recent respiratory infections or changes in her medication. On examination, her vital signs are normal, and there are scattered wheezes on auscultation. Spirometry shows a reduced FEV1/FVC ratio that improves significantly after bronchodilator administration. What is the most appropriate next step in the management of this patient?

A. Increase the dose of inhaled corticosteroids
B. Start oral corticosteroids
C. Refer for allergy testing
D. Add a long-acting beta-agonist (LABA)
E. Prescribe a leukotriene receptor antagonist
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An 8-year-old girl presents with chronic night cough and wheezing, with possible asthma. What is the minimum age for spirometry?

A. 8 years old
B. 7 years old
C. 5 years old
D. 6 years old
E. 4 years old
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A 2-year-old child is brought to the emergency department by their parents due to a persistent cough, wheezing, and difficulty breathing that has worsened over the past two days. The child has a known history of eczema and multiple food allergies, including peanuts and eggs. On examination, the child appears in mild respiratory distress with nasal flaring and intercostal retractions. Auscultation of the chest reveals bilateral wheezing. The child is afebrile, with a respiratory rate of 40 breaths per minute, heart rate of 120 bpm, and oxygen saturation of 94% on room air. A chest X-ray shows hyperinflation but no focal consolidation. Which of the following is the most likely diagnosis?

A. Bronchiolitis
B. Cystic fibrosis
C. Foreign body aspiration
D. Asthma
E. Pneumonia
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A 35-year-old woman presents to the emergency department with a 3-day history of fever, chills, and a productive cough with greenish sputum. She has a history of asthma and is currently on inhaled corticosteroids. On examination, her temperature is 38.5°C, blood pressure is 120/80 mmHg, heart rate is 110 bpm, and respiratory rate is 24 breaths per minute. Auscultation of the chest reveals wheezing and crackles in the right lower lung field. A chest X-ray shows consolidation in the right lower lobe. What is the most appropriate initial antibiotic therapy for this patient, considering her asthma and current presentation?

A. Azithromycin
B. Amoxicillin-clavulanate
C. Ciprofloxacin
D. Levofloxacin
E. Doxycycline
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A 4-year-old boy is brought to the clinic by his parents due to a persistent itchy rash on his arms and legs. The rash has been present for several weeks and seems to worsen at night. The child has a history of asthma and allergic rhinitis. On examination, there are erythematous, scaly patches with excoriations on the flexural surfaces of his arms and legs. What is the most likely diagnosis?

A. Scabies
B. Psoriasis
C. Contact dermatitis
D. Atopic dermatitis
E. Tinea corporis
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A 5-year-old child with a known history of asthma presents with acute shortness of breath and wheezing after playing outside. What is the most appropriate initial treatment?

A. Administer intravenous magnesium sulfate
B. Administer salbutamol via a spacer
C. Administer ipratropium bromide
D. Administer oral prednisone
E. Start oxygen therapy
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A 6-year-old child with a history of asthma presents with increased wheezing and difficulty breathing after exposure to cold air. What is the most appropriate immediate management?

A. Provide oxygen therapy
B. Start oral corticosteroids
C. Refer to the emergency department
D. Administer ipratropium bromide
E. Administer salbutamol via a spacer
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A 10-year-old boy with a history of asthma presents to the emergency department with wheezing and shortness of breath. His mother reports that he has been using his salbutamol inhaler more frequently over the past two days. On examination, he has a respiratory rate of 28 breaths per minute, and his oxygen saturation is 92% on room air. What is the most appropriate initial management step?

A. Administer nebulized salbutamol
B. Administer intravenous magnesium sulfate
C. Provide supplemental oxygen
D. Increase the dose of inhaled corticosteroids
E. Start oral corticosteroids
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A 35-year-old woman presents to her GP with worsening shortness of breath, cough, and wheeze over 2 days, requiring her salbutamol reliever daily and waking her at night. Her PEF is 60% of her personal best. She is alert, speaking in sentences, RR 22, HR 95. Based on Australian guidelines, what is the most appropriate initial management step?

A. Prescribe a course of oral prednisolone.
B. Order a chest X-ray to rule out pneumonia.
C. Increase the dose of her regular inhaled corticosteroid.
D. Arrange immediate transfer to the nearest emergency department.
E. Administer inhaled salbutamol via spacer and reassess clinical status and PEF.
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A 10-year-old boy with a known history of asthma presents to the emergency department. He developed symptoms three days after a viral upper respiratory tract infection. On examination, he is tachypnoeic (respiratory rate 48 breaths/min), tachycardic (heart rate 130 bpm), and hypoxic with an oxygen saturation of 91% on room air. He is speaking only in short phrases but remains alert and is afebrile. Auscultation reveals a widespread wheeze throughout his chest. A COVID swab performed yesterday was negative. Which investigation is the most appropriate next step in the immediate management of this patient?

A. Full Blood Count (FBC)
B. No further diagnostics are required immediately.
C. Chest X-ray
D. Peak Expiratory Flow (PEF) measurement
E. Arterial Blood Gas (ABG)
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A 6-year-old boy is brought to the emergency department by his parents due to sudden onset wheezing and difficulty breathing. He has a history of atopic dermatitis and allergic rhinitis. His parents mention that he was playing outside when the symptoms began. On examination, he is in mild respiratory distress with a respiratory rate of 28 breaths per minute, oxygen saturation of 94% on room air, and bilateral wheezing on auscultation. There is no fever, and his heart rate is 110 bpm. Which of the following is the most likely diagnosis?

A. Asthma exacerbation
B. Bacterial pneumonia
C. Foreign body aspiration
D. Anaphylaxis
E. Viral bronchiolitis
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A 4-year-old boy is brought to the pediatrician by his parents due to a persistent cough and wheezing for the past two weeks. The symptoms started after he had a cold. He has no significant past medical history and is up to date with his vaccinations. On examination, he is afebrile, with mild respiratory distress and bilateral wheezing on auscultation. What is the most appropriate initial treatment?

A. Inhaled salbutamol
B. Observation and reassurance
C. Oral corticosteroids
D. Oral antibiotics
E. Inhaled corticosteroids
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A 5-year-old boy presents with wheezing, shortness of breath, and a history of recurrent respiratory infections. His symptoms worsen with exercise and during the night. What is the most likely diagnosis?

A. Cystic fibrosis
B. Bronchiolitis
C. Asthma
D. Viral pneumonia
E. Foreign body aspiration
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A 45-year-old woman presents to the emergency department with a 3-day history of fever, productive cough with greenish sputum, and pleuritic chest pain. She has a history of asthma and is currently on salbutamol and fluticasone inhalers. On examination, her temperature is 38.5°C, respiratory rate is 24 breaths per minute, and oxygen saturation is 92% on room air. Auscultation reveals decreased breath sounds and crackles in the right lower lung field. A chest X-ray shows a right lower lobe consolidation. What is the most appropriate initial antibiotic therapy for this patient, considering Australian guidelines?

A. Doxycycline
B. Ceftriaxone
C. Amoxicillin-clavulanate
D. Azithromycin
E. Ciprofloxacin
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A 3-year-old child is brought to the general practice clinic by his parents due to recurrent episodes of wheezing and cough, particularly following viral upper respiratory tract infections. The child has had multiple similar episodes over the past year, each resolving with bronchodilator therapy. There is no history of eczema or allergic rhinitis, and the family history is unremarkable for atopic conditions. On examination, the child appears well between episodes, with normal growth parameters and no signs of respiratory distress. Auscultation of the chest reveals clear lung fields without wheezes or crackles. Which of the following is the most likely underlying condition?

A. Bronchiolitis
B. Viral-induced wheeze
C. Foreign body aspiration
D. Cystic fibrosis
E. Asthma
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