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geriatrics

Practice targeted AMC-style multiple-choice questions on geriatrics.

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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 72-year-old female presents with right leg pain and skin changes after starting warfarin for atrial fibrillation. Her INR is 3.5. Examination reveals the findings in the image. What is the MOST appropriate next step in management?

A. Administer vitamin K and discontinue warfarin
B. Elevate the leg and apply compression bandages
C. Prescribe a broad-spectrum antibiotic
D. Apply topical corticosteroids
E. Increase the dose of warfarin
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 75-year-old male presents with worsening dysphagia. An X-ray is performed (shown). What is the most appropriate initial investigation?

A. Esophageal manometry
B. 24-hour pH monitoring
C. Upper endoscopy
D. CT chest
E. Barium swallow
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for follow-up after experiencing intermittent episodes of right upper quadrant colicky pain over the past year, which have since resolved. She denies any current pain, fever, jaundice, or changes in bowel habits. Physical examination is unremarkable, and recent liver function tests are within normal limits. An elective abdominal ultrasound was performed, yielding the image shown. Considering the clinical context and the findings demonstrated, what is the most appropriate next step in her management?

A. Discharge with advice to return if symptoms recur
B. ERCP for stone extraction
C. Initiate ursodeoxycholic acid therapy
D. MRCP to further delineate the biliary anatomy
E. Elective laparoscopic cholecystectomy
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 72-year-old male presents to the emergency department complaining of sudden onset shortness of breath and right-sided chest pain. He reports that the pain started acutely this morning and has been gradually worsening. He has a history of atrial fibrillation and has been taking warfarin for the past 5 years. He denies any recent trauma or injury. On examination, his vital signs are: heart rate 110 bpm, blood pressure 100/60 mmHg, respiratory rate 28 breaths per minute, oxygen saturation 88% on room air. Auscultation reveals decreased breath sounds on the right side. The patient is pale and diaphoretic. A chest X-ray was initially performed, followed by the image shown. Given the clinical presentation and the findings on the image, what is the MOST appropriate next step in management?

A. Administer protamine sulfate
B. Perform a thoracentesis
C. Administer intravenous antibiotics
D. Order a ventilation/perfusion scan
E. Insert a chest tube
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An 80-year-old woman is brought to the emergency department from a nursing home due to increased lethargy and confusion over the past 24 hours. Her history includes dementia, hypertension, and type 2 diabetes. Nursing staff report poor oral intake for 48 hours and a recent cough. On examination, she is drowsy but rousable. Her vital signs are: BP 85/50 mmHg, HR 110 bpm, RR 22 breaths/min, Temp 37.8°C, SpO2 94% on air. Capillary refill time is 4 seconds. Chest auscultation reveals decreased breath sounds at the bases. Abdomen is soft. Urine dipstick shows leukocytes and nitrites. She is on lisinopril and metformin. What is the most appropriate initial management step?

A. Administer intravenous fluid bolus (e.g., 500 mL crystalloid)
B. Administer oral rehydration solution
C. Obtain a chest X-ray and urine culture
D. Discontinue lisinopril and monitor blood pressure
E. Administer broad-spectrum intravenous antibiotics
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A 68-year-old woman with a history of hypertension and heart failure is being treated with an ACE inhibitor. Her recent blood tests show a potassium level of 5.8 mmol/L. Which of the following is the most appropriate initial step in managing her hyperkalemia?

A. Prescribe a loop diuretic such as furosemide
B. Administer intravenous calcium gluconate
C. Immediately commence haemodialysis
D. Review and potentially reduce or discontinue the ACE inhibitor
E. Administer intravenous insulin and glucose
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 78-year-old male on warfarin presents with dyspnea and pleuritic chest pain after a fall. INR is 7.0. A chest CT is performed (image attached). After initial resuscitation, what is the MOST appropriate next step?

A. Observe and repeat CT chest in 6 hours
B. Administer intravenous vitamin K and prothrombin complex concentrate
C. Perform bronchoscopy with bronchoalveolar lavage
D. Administer intravenous protamine sulfate
E. Insert an intercostal chest drain
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A 70-year-old woman with a history of diabetes presents with fever, cough, and weight loss. A chest X-ray shows a cavitary lesion in the right upper lobe. What is the most likely diagnosis?

A. Sarcoidosis
B. Lung cancer
C. Tuberculosis
D. Lung abscess
E. Pneumocystis pneumonia
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old woman presents to the emergency department with a 2-day history of worsening right upper quadrant abdominal pain radiating to her back, associated with fever, chills, and yellowing of her eyes. She denies prior similar episodes but reports occasional post-prandial discomfort. On examination, she is jaundiced and tender in the right upper quadrant. Vital signs are: temperature 38.5°C, heart rate 110 bpm, blood pressure 110/70 mmHg, respiratory rate 20 breaths per minute, and oxygen saturation 97% on room air. Initial laboratory investigations reveal: white blood cell count 14,000/µL, total bilirubin 6.0 mg/dL, alkaline phosphatase 450 U/L, ALT 300 U/L, and AST 250 U/L. An ERCP is performed, and the image is obtained. Following successful intervention to relieve the obstruction, the patient's symptoms begin to improve. Considering the likely underlying cause of this presentation and the findings during the procedure, what is the MOST appropriate next step in managing this patient's condition?

A. Referral for medical dissolution therapy for gallstones
B. Elective laparoscopic cholecystectomy during the same admission or shortly after discharge
C. Long-term antibiotic therapy to prevent recurrence
D. Discharge home with pain relief and follow-up in general practice
E. Repeat ERCP in 3 months to check for residual stones
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A 68-year-old woman is admitted to the hospital with confusion and muscle weakness. Her medications include hydrochlorothiazide for hypertension. Initial laboratory results show: Sodium 120 mmol/L (Normal: 135-145 mmol/L), Potassium 3.8 mmol/L (Normal: 3.5-5.0 mmol/L), Chloride 90 mmol/L (Normal: 95-105 mmol/L). What is the most likely cause of her hyponatremia?

A. Hyperglycemia
B. Thiazide-induced SIADH
C. Primary polydipsia
D. Renal failure
E. Adrenal insufficiency
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A 78M presents with cough, fever, confusion. BP 90/60, RR 30, Temp 38.5, SpO2 90% on air. CXR shows LUL consolidation. What is the most appropriate initial management?

A. Arrange urgent viral PCR testing
B. Initiate oral antibiotics and admit to general ward
C. Discharge home with oral antibiotics
D. Perform urgent bronchoscopy
E. Initiate IV antibiotics and assess for ICU admission
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An 80-year-old presents with cough, fever, and new confusion. CXR shows right lower lobe consolidation. What is the most appropriate initial antibiotic regimen?

A. Piperacillin-tazobactam
B. Amoxicillin
C. Doxycycline
D. Ciprofloxacin
E. Ceftriaxone and Azithromycin
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 75-year-old presents with a 4-month history of increasing dysphagia to solids, occasional regurgitation, and chronic cough, particularly at night. He denies significant weight loss or chest pain. Past medical history includes type 2 diabetes and hypertension. Medications are metformin and perindopril. Physical examination is unremarkable. A chest X-ray is performed as part of the initial assessment. Considering the clinical presentation and the radiographic findings, which of the following investigations is most appropriate at this stage?

A. Barium swallow study
B. Oesophageal manometry
C. Oesophago-gastro-duodenoscopy
D. High-resolution CT chest
E. Ambulatory ECG monitoring
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An 82-year-old woman from an aged care facility presents with a 2-day history of increased confusion and lethargy. Her baseline is independent living with mild cognitive impairment. She has a chronic cough but no recent change in sputum. Vital signs: T 37.8°C, HR 95 bpm, BP 110/70 mmHg, RR 22 breaths/min, SpO2 92% on room air. Chest examination reveals decreased breath sounds at the right base. Given the clinical presentation and setting, which of the following is the most appropriate initial management step while awaiting the chest X-ray result?

A. Perform a CT scan of the chest to confirm the diagnosis.
B. Administer empiric broad-spectrum antibiotics covering typical and atypical pathogens.
C. Transfer to a tertiary hospital for specialist respiratory review.
D. Administer supplemental oxygen and monitor vital signs closely.
E. Obtain sputum culture and sensitivity before initiating antibiotics.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old woman presents with 3 days of left lower quadrant pain. She reports mild nausea but no vomiting or fever. On examination, she is afebrile, BP 130/80, HR 78, O2 sat 98% on air. There is localised tenderness in the LLQ. Bloods show WCC 13.2, CRP 45. A CT scan is performed. Considering the clinical presentation and the findings demonstrated in the image, what is the most appropriate initial management plan?

A. Discharge with analgesia and advice to return if symptoms worsen, without antibiotics.
B. Outpatient management with oral antibiotics and analgesia.
C. Admission for intravenous antibiotics and observation.
D. Urgent colonoscopy to assess the extent of disease.
E. Surgical consultation for potential colectomy.
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A 78-year-old man with a history of chronic atrial fibrillation and hypertension presents to the emergency department with sudden onset of severe pain, numbness, and coldness in his left leg, starting approximately 3 hours ago. He is currently taking aspirin 100mg daily. On examination, his left foot and lower calf are pale and cool to touch. Pedal pulses are absent, popliteal pulse is weak. Sensation is decreased below the ankle, and motor function is preserved but weak. Capillary refill in the toes is delayed. His heart rate is irregularly irregular at 95 bpm, blood pressure 140/85 mmHg. What is the most appropriate initial management step?

A. Initiate intravenous unfractionated heparin and consult vascular surgery urgently.
B. Administer a bolus of intravenous fluid and analgesia.
C. Start a continuous infusion of alteplase.
D. Order an urgent CT angiography of the left lower limb.
E. Arrange for an urgent venous duplex ultrasound to rule out deep vein thrombosis.
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A 62-year-old woman presents with tiredness and is found to have B12 deficiency. What is the likely associated condition?

A. Pernicious anemia
B. Recent viral infection
C. Sulphonylurea use
D. Low vegetable, high meat diet.
E. Iron deficiency anemia
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 72-year-old male presents to the clinic complaining of a painless swelling in his right groin that has been present for several years. He reports that the swelling occasionally increases in size with prolonged standing or heavy lifting, but it usually reduces when he lies down. He denies any acute pain, nausea, vomiting, or changes in bowel habits. His past medical history includes well-controlled type 2 diabetes mellitus and a remote appendectomy. On physical examination, his vital signs are within normal limits. Abdominal examination is unremarkable. Examination of the groin reveals the finding shown in the image. The swelling is easily reducible when the patient is supine. Which of the following is the MOST appropriate initial management strategy for this patient?

A. Urgent surgical exploration
B. Elective surgical repair
C. Referral for watchful waiting with lifestyle modifications
D. Initiation of high-fiber diet and stool softeners
E. Prescription of a truss for symptomatic relief
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An 80-year-old presents with cough, fever, and new confusion. Vital signs: T 38.5°C, HR 110, BP 100/60, RR 28, SpO2 90% on air. Chest X-ray shows consolidation. What is the most appropriate initial management step?

A. Oral antibiotics and outpatient management
B. Chest CT scan
C. Bronchoscopy
D. Sputum culture and sensitivity testing
E. Intravenous antibiotics and hospital admission
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 75-year-old male with a history of a reducible groin hernia presents with acute abdominal pain. The provided image was taken. What is the most likely complication?

A. Indirect hernia
B. Sliding hernia
C. Richter's hernia
D. Strangulation
E. Direct hernia
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 78-year-old male presents with persistent vomiting and epigastric pain. He reports a history of NSAID use for chronic arthritis. An X-ray is performed. Which of the following is the MOST likely complication associated with this finding?

A. Aortic dissection
B. Gastric volvulus
C. Pneumonia
D. Pericarditis
E. Esophageal stricture
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 78-year-old female on warfarin for chronic atrial fibrillation presents to the emergency department with a 24-hour history of increasing pain and discolouration in her right lower leg. She denies trauma or recent falls. Her INR this morning was 2.5 (target 2.0-3.0). Vital signs are stable: BP 130/80, HR 75, RR 16, Temp 36.8°C. Examination reveals the findings shown in the image. Considering the patient's history, current medication, and the clinical appearance depicted, what is the most appropriate immediate management?

A. Discontinue warfarin, administer Vitamin K, and initiate heparin or LMWH.
B. Arrange urgent surgical debridement of the affected area.
C. Increase the dose of warfarin and monitor INR closely.
D. Initiate broad-spectrum intravenous antibiotics.
E. Perform a Doppler ultrasound of the leg veins.
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 75-year-old female presents to the emergency department with a 24-hour history of worsening colicky abdominal pain, nausea, and multiple episodes of bilious vomiting. She reports no passage of flatus or stool for the past 18 hours. Her past medical history includes an open appendectomy 30 years ago and a hysterectomy 10 years ago. On examination, she is afebrile, heart rate 92 bpm, blood pressure 130/80 mmHg, respiratory rate 18/min, oxygen saturation 98% on room air. Her abdomen is distended and diffusely tender to palpation, with high-pitched tinkling bowel sounds on auscultation. A plain abdominal X-ray series, including the image provided, was obtained. Considering the patient's clinical presentation and the findings demonstrated in the provided image, which of the following represents the most appropriate immediate next step in her management?

A. Administer a large volume enema
B. Administer broad-spectrum intravenous antibiotics
C. Order a CT scan of the abdomen and pelvis with intravenous contrast
D. Proceed directly to exploratory laparotomy
E. Insert a nasogastric tube for decompression
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 68-year-old woman recently started on warfarin for a pulmonary embolism presents with a painful, rapidly expanding purpuric lesion on her thigh, which developed two days ago. Her INR is 2.5. She has no history of trauma to the area. Considering the clinical presentation and the appearance of the lesion, what is the most likely underlying pathophysiological process?

A. Allergic vasculitis secondary to warfarin
B. Protein C deficiency leading to paradoxical thrombosis
C. Vitamin K deficiency exacerbating bleeding
D. Direct toxic effect of warfarin on dermal capillaries
E. Heparin-induced thrombocytopenia causing microthrombi
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A 60-year-old woman presents to the clinic with a 2-month history of progressive shortness of breath and a dry cough. She has a history of rheumatoid arthritis and is currently on methotrexate and low-dose prednisone. On examination, she has fine inspiratory crackles at the lung bases. A high-resolution CT scan of the chest shows reticular opacities and honeycombing predominantly in the lower lobes. What is the most likely diagnosis?

A. Chronic obstructive pulmonary disease (COPD)
B. Congestive heart failure
C. Pulmonary embolism
D. Interstitial lung disease secondary to rheumatoid arthritis
E. Pneumonia
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A 72-year-old woman is admitted to the hospital with increasing confusion and generalized weakness over the past week. Her medical history includes hypertension, for which she takes hydrochlorothiazide 25mg daily. On examination, she is lethargic but arousable. Her blood pressure is 110/70 mmHg, heart rate is 88 bpm, and respiratory rate is 16 breaths per minute. Neurological examination reveals decreased reflexes. Initial laboratory investigations reveal the following: Sodium 118 mmol/L, Potassium 3.8 mmol/L, Chloride 85 mmol/L, Bicarbonate 24 mmol/L, BUN 15 mg/dL, Creatinine 0.8 mg/dL, Glucose 90 mg/dL. Urine osmolality is 600 mOsm/kg. Serum osmolality is 250 mOsm/kg. Which of the following is the most appropriate initial management strategy?

A. Fluid restriction and monitoring of sodium levels
B. Administration of desmopressin (DDAVP)
C. Administration of intravenous normal saline at a rapid infusion rate
D. Administration of a loop diuretic such as furosemide
E. Administration of intravenous 3% hypertonic saline at a rate of 50 mL/hour
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 68-year-old man with known alcoholic cirrhosis presents for routine surveillance. He reports mild fatigue. Liver function tests are within his baseline (Child-Pugh A). Alpha-fetoprotein is 150 ng/mL. The provided images are obtained. Considering the clinical context and the findings demonstrated in the images, which of the following treatment modalities is most likely to be considered first for this patient?

A. Transarterial chemoembolisation (TACE)
B. Surgical resection
C. Palliative care
D. Systemic targeted therapy (e.g., Sorafenib)
E. Liver transplantation assessment
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 68-year-old patient presents with chronic intermittent upper abdominal discomfort, postprandial fullness, and occasional regurgitation. Physical examination is unremarkable. A chest radiograph is performed as part of the workup. Considering the radiographic findings in the context of the patient's presentation, what is the most appropriate next step in management?

A. Initiate a trial of high-dose proton pump inhibitor therapy.
B. Advise dietary modifications and schedule follow-up in 3 months.
C. Referral for upper gastrointestinal endoscopy.
D. Arrange urgent surgical consultation for repair.
E. Request a barium swallow study to assess anatomy.
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 78-year-old male on warfarin for atrial fibrillation presents to the emergency department with sudden onset of severe dyspnoea and right-sided pleuritic chest pain. He denies trauma. On examination, he is tachypnoeic, oxygen saturation is 92% on room air. Blood pressure 110/70 mmHg, heart rate 95 bpm. Chest examination reveals decreased breath sounds on the right. A CT scan of the chest is performed. Considering the patient's clinical presentation, medical history, and the findings demonstrated in the provided image, which of the following represents the most appropriate immediate management strategy?

A. Arrange for urgent bronchoscopy to investigate airway obstruction.
B. Increase warfarin dose and monitor INR.
C. Observe closely in the emergency department with serial chest X-rays.
D. Administer broad-spectrum antibiotics and arrange for thoracentesis.
E. Administer Vitamin K and Prothrombinex (PCC) and arrange for chest tube insertion.
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A 78-year-old woman with a history of heart failure (reduced ejection fraction), type 2 diabetes, and recent hospitalisation for pneumonia presents to her GP with increasing fatigue and a single episode of dizziness leading to a fall without loss of consciousness. Her current medications are Digoxin 125 mcg daily, Furosemide 40 mg daily, Ramipril 5 mg daily, Metformin 500 mg BD, and Amoxicillin 500 mg TDS (started 5 days ago for pneumonia). An ECG in clinic shows sinus rhythm, rate 70 bpm, and a QTc of 530 ms. An ECG from 6 months prior had a QTc of 440 ms. Recent laboratory tests show Na 138 mmol/L, K 4.2 mmol/L, Mg 0.9 mmol/L, Ca 2.3 mmol/L, Creatinine 90 µmol/L, and Digoxin level 1.1 ng/mL. Considering the clinical context and investigations, which of the following is the most likely significant contributor to the observed QTc prolongation?

A. Ramipril
B. Underlying heart failure
C. Amoxicillin
D. Digoxin
E. Furosemide
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old patient presents with intermittent chest discomfort and increasing shortness of breath, particularly after meals. Vitals are stable. Physical examination is unremarkable. A chest X-ray is performed. Considering the radiographic findings in the context of the patient's symptoms, what is the most appropriate next step in management?

A. Trial of high-dose proton pump inhibitors
B. High-resolution CT chest
C. Barium swallow study
D. Referral for surgical assessment and repair
E. Urgent cardiac catheterisation
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An 82-year-old man with a history of stroke presents with new onset confusion, a mild cough, and a temperature of 37.8°C. A chest X-ray reveals a right lower lobe infiltrate. Which of the following is the most appropriate initial management step?

A. Initiate empiric broad-spectrum antibiotics
B. Order urgent sputum culture
C. Administer IV fluids and monitor
D. Discharge home with oral paracetamol
E. Arrange urgent physiotherapy review
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old woman presents with a 2-day history of worsening right upper quadrant pain radiating to her back, associated with nausea and a low-grade fever. On examination, she is jaundiced and has tenderness in the right upper quadrant. Laboratory tests show a total bilirubin of 75 µmol/L, ALP 350 U/L, ALT 200 U/L, and WCC 13.5 x 10^9/L. An urgent ERCP is performed, during which the image is captured. Following successful endoscopic clearance and clinical improvement, which of the following is the MOST appropriate long-term management strategy?

A. Long-term treatment with ursodeoxycholic acid
B. Repeat ERCP with cholangiogram in 3 months
C. Regular monitoring of liver function tests every 6 months
D. Strict adherence to a low-fat diet
E. Elective laparoscopic cholecystectomy
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with a 3-day history of abdominal pain, distension, and obstipation, with a background of multiple abdominal surgeries. Vitals show HR 110, BP 110/70, T 37.8°C. Physical exam reveals a distended abdomen with high-pitched bowel sounds. An upright abdominal X-ray is shown. Considering the clinical findings and the radiographic appearance, which of the following potential complications is the MOST critical to evaluate for urgently?

A. Acute kidney injury
B. Severe electrolyte imbalance
C. Bowel ischaemia or strangulation
D. Deep vein thrombosis
E. Aspiration pneumonia
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

An 82-year-old patient presents to their GP with a 3-month history of intermittent retrosternal chest discomfort, often described as a burning sensation, worse after meals and when lying flat. They also report mild shortness of breath on exertion and occasional regurgitation, but deny significant dysphagia or weight loss. Past medical history includes hypertension and osteoarthritis. Medications are perindopril and paracetamol. On examination, vital signs are stable (BP 130/80, HR 75, RR 16, SpO2 97% on air), and lung sounds are clear. A chest X-ray is performed as part of the workup. Based on the clinical context and the findings demonstrated in the image, what is the most appropriate next step in investigation?

A. Reassure the patient that the X-ray is normal and advise lifestyle modifications
B. Oesophago-gastro-duodenoscopy (OGD)
C. Refer for formal cardiac stress testing
D. Commence a trial of high-dose proton pump inhibitor (PPI) therapy
E. Perform pulmonary function tests (PFTs)
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 70-year-old woman presents with a persistent, slowly enlarging skin lesion on her left chest wall, which she first noticed several months ago. She underwent a left simple mastectomy for invasive ductal carcinoma 12 years prior. Physical examination reveals the findings depicted. A recent biopsy of the lesion confirmed the presence of Paget cells. She has no other new symptoms. Her vital signs are stable. Considering the patient's history and the biopsy findings, which of the following investigations is the most appropriate next step in her management?

A. Observation with regular follow-up
B. PET-CT scan for staging
C. Wide local excision of the lesion
D. Topical corticosteroid cream
E. Repeat biopsy of the lesion
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An 98-year-old lady with cognitive impairment has had 2 episodes of acute delirium, is pacing, and is vomiting blood. What is the immediate management?

A. Give oral antiemetics and observe.
B. Start IV fluids and wait for review by GP.
C. Call 000 and transfer to the regional hospital.
D. SC line and administer haloperidol, morphine, and midazolam.
E. Arrange an urgent gastroscopy for tomorrow.
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A 70-year-old man presents with a vertebral fracture after a minor fall. Reviewing risk factors for osteoporosis, which of the following is the most likely risk factor?

A. Absence of family history of osteoporosis.
B. High dietary calcium intake
C. Previous fragility fracture
D. Regular vigorous exercise
E. High BMI
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male presents with a painful groin mass and constipation. The provided image was taken. What is the most appropriate next step?

A. CT angiography to rule out vascular compromise
B. Manual reduction of the mass
C. Surgical consultation for possible bowel resection
D. Observation with serial abdominal exams
E. Stool softeners and increased fiber intake
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

An 82-year-old woman is admitted to the hospital with increasing shortness of breath and intermittent chest discomfort over the past week. She reports some difficulty swallowing larger food boluses recently but denies significant heartburn. Her past medical history includes hypertension and osteoarthritis. On examination, her vital signs are stable: BP 135/85 mmHg, HR 78 bpm, RR 18/min, SpO2 94% on room air, Temp 36.8°C. Auscultation of the chest reveals decreased breath sounds at the left base. A central venous catheter is noted in the right subclavian vein. Initial blood tests show a mild normocytic anaemia (Hb 105 g/L) and normal inflammatory markers. An urgent imaging study is performed. Considering the clinical presentation and the findings on the imaging study, which of the following is the most likely underlying cause of the patient's anaemia?

A. Chronic mucosal erosion within the displaced viscus
B. Vitamin B12 deficiency secondary to impaired absorption from dysphagia
C. Anaemia of chronic disease exacerbated by her underlying osteoarthritis
D. Acute blood loss from a peptic ulcer distal to the pylorus
E. Microangiopathic haemolytic anaemia associated with the indwelling central venous catheter
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A 68-year-old man with a history of diverticulosis presents with recurrent, large volume rectal bleeding. Initial colonoscopy failed to identify or control the source. He remains haemodynamically stable after resuscitation. What is the most appropriate next step in management?

A. Repeat colonoscopy with epinephrine injection
B. Administration of intravenous octreotide
C. Initiation of high-dose proton pump inhibitor therapy
D. Urgent surgical colectomy
E. Angiography with embolization
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An 80-year-old presents with CAP. CURB-65 score is 3. What is the most appropriate initial management?

A. Outpatient management with observation only
B. Inpatient management with IV antibiotics
C. Outpatient management with oral antibiotics
D. Inpatient management with oral antibiotics
E. Admission to ICU
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 68-year-old patient on warfarin for a recent DVT presents with a painful, rapidly expanding skin lesion on their leg that started 48 hours ago. Their INR is 2.9. Given the clinical context and the appearance of the lesion, what is the most appropriate immediate management step?

A. Increase the warfarin dose and monitor INR closely.
B. Switch warfarin to a direct oral anticoagulant (DOAC).
C. Obtain a skin biopsy and continue current management.
D. Apply topical antibiotics and continue warfarin.
E. Stop warfarin, administer Vitamin K, and initiate heparin.
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A 70-year-old man with a history of hypertension and heart failure is being managed with an ACE inhibitor. He presents to the emergency department complaining of dizziness, especially when standing up. His blood pressure is 90/60 mmHg, and his other vital signs are stable. Which of the following is the most appropriate initial step in managing this patient?

A. Order an ECG to rule out cardiac arrhythmia
B. Prescribe compression stockings
C. Review and potentially reduce the dose of the ACE inhibitor
D. Administer an intravenous bolus of normal saline
E. Start fludrocortisone
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 72-year-old woman with a history of well-controlled hypertension and type 2 diabetes presents to the emergency department with sudden onset of visual disturbance and mild weakness. She describes the visual issue as a loss of vision in the left half of her visual field, which began approximately 3 hours ago. She also notes some difficulty moving her right arm and leg, which started around the same time. On examination, her vital signs are stable: BP 135/85 mmHg, HR 78 bpm, RR 16/min, Temp 36.8°C, SpO2 98% on room air. Neurological examination confirms a left homonymous hemianopia and mild right hemiparesis (MRC grade 4/5) affecting both upper and lower limbs. Sensation is intact. Reflexes are symmetrical, and plantar responses are flexor. A non-contrast CT head was unremarkable for acute haemorrhage or established infarction. Subsequent CT angiography identified a cerebral aneurysm in a location consistent with her symptoms, and she was taken for endovascular coiling. The procedure was completed approximately 6 hours after symptom onset. The image provided is a digital subtraction angiogram obtained immediately following the coiling procedure. Despite the intervention, her left homonymous hemianopia and right hemiparesis persist without significant improvement. Considering the findings demonstrated in the post-procedure imaging in the context of her ongoing neurological deficits, which of the following is the MOST appropriate immediate management step?

A. Perform a repeat cerebral angiogram or high-resolution cross-sectional imaging to assess the residual sac and flow dynamics.
B. Assume the persistent symptoms are unrelated to the treated lesion and investigate for alternative causes such as carotid artery stenosis.
C. Administer intravenous alteplase given the persistent symptoms and recent onset.
D. Initiate aggressive inpatient stroke rehabilitation therapy immediately.
E. Discharge the patient home with urgent outpatient follow-up with neurology.
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 72-year-old woman on warfarin for chronic atrial fibrillation presents with a painful, rapidly expanding lesion on her right lower leg that began two days ago, shortly after her warfarin dose was increased. Her vital signs are stable, and her INR is within the therapeutic range. Considering the clinical presentation and the appearance of the lesion shown, what is the most appropriate immediate management?

A. Administer broad-spectrum antibiotics and arrange urgent surgical debridement.
B. Switch warfarin to a direct oral anticoagulant (DOAC).
C. Discontinue warfarin, administer vitamin K, and initiate heparin.
D. Continue warfarin at the current dose and monitor closely.
E. Reduce the warfarin dose and add aspirin.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

An asymptomatic 70-year-old male undergoes a CT scan of the abdomen as part of an investigation for mild, intermittent lower back pain. His vital signs are stable, and physical examination is unremarkable. Considering the findings on the provided image, what is the most appropriate next step in this patient's management?

A. No further imaging required; manage back pain symptomatically.
B. Annual abdominal ultrasound surveillance.
C. Urgent referral for vascular surgical assessment.
D. Referral for a follow-up CT angiogram in 2 years.
E. Repeat CT scan in 6 months.
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An 82-year-old man with a history of COPD and mild dementia is brought to the emergency department by his family due to increased confusion over 24 hours. He has had a low-grade fever (37.8°C) and a mild cough for 3 days. On examination, he is drowsy but rousable. His oxygen saturation is 90% on room air. Chest auscultation reveals decreased breath sounds at the bases. A chest X-ray shows bilateral lower lobe infiltrates. His CURB-65 score is 3. Considering the patient's presentation and CURB-65 score, what is the most appropriate initial management plan?

A. Admission to hospital for observation and oral antibiotics.
B. Discharge home with supportive care and review in 24 hours.
C. Admission to ICU for mechanical ventilation and broad-spectrum antibiotics.
D. Outpatient management with oral antibiotics and close follow-up.
E. Admission to hospital with intravenous antibiotics.
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A 72-year-old man presents with 4 weeks of shortness of breath (SOB), shoulder pain, weight loss, cervical lymphadenopathy, and finger clubbing. What is the likely diagnosis?

A. Lung cancer
B. Tuberculosis
C. Multiple myeloma
D. Lymphoma
E. Sarcoidosis
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A 66-year-old man, active with a good diet, whose mother had osteoporosis at age 91, wants to check his osteoporosis risk. What risk factors prompt a bone mineral density (BMD) test?

A. Asthma
B. Rheumatoid arthritis
C. Generalized anxiety disorder
D. Type 2 Diabetes Mellitus
E. Hypertension
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