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hypertension

Practice targeted AMC-style multiple-choice questions on hypertension.

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A 70-year-old man presents to the emergency department with sudden onset of severe headache, nausea, and vomiting. He has a history of hypertension and is currently on antihypertensive medication. On examination, he is drowsy and has a blood pressure of 180/110 mmHg. A CT scan of the brain shows a hyperdense area in the right basal ganglia. What is the most likely diagnosis?

A. Intracerebral hemorrhage
B. Ischemic stroke
C. Migraine with aura
D. Transient ischemic attack
E. Subarachnoid hemorrhage
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A 65-year-old man with hypertension is started on a medication that blocks the angiotensin-converting enzyme (ACE). What is the most common side effect of this class of drugs?

A. Hyperkalemia
B. Acute kidney injury
C. Angioedema
D. Hypotension
E. Dry cough
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A 72-year-old man with a history of chronic kidney disease stage 4, hypertension, and type 2 diabetes presents to the emergency department with confusion and lethargy. His family reports that he has been increasingly drowsy over the past two days. On examination, he is disoriented to time and place, with a blood pressure of 150/90 mmHg, heart rate of 88 bpm, respiratory rate of 20 breaths per minute, and temperature of 36.5°C. Laboratory tests reveal: sodium 130 mmol/L, potassium 5.8 mmol/L, bicarbonate 18 mmol/L, urea 25 mmol/L, creatinine 450 µmol/L, and glucose 8 mmol/L. An ECG shows peaked T waves. What is the most appropriate immediate management step?

A. Administer oral sodium polystyrene sulfonate
B. Administer intravenous calcium gluconate
C. Initiate hemodialysis
D. Start intravenous insulin and glucose
E. Administer intravenous sodium bicarbonate
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male presents to his general practitioner complaining of mild, chronic lower back pain that has been present for several months. He describes the pain as a dull ache, worse with prolonged standing. He has a significant past medical history including hypertension, hyperlipidemia, and a 50-pack-year smoking history, all of which are currently managed with medications. He denies any acute abdominal pain, pulsatile sensation, or leg symptoms. On physical examination, his vital signs are stable: blood pressure 135/85 mmHg, heart rate 72 bpm, respiratory rate 14 breaths/min, and oxygen saturation 99% on room air. Abdominal examination is soft, non-tender, with no palpable masses. Peripheral pulses are symmetric and strong. As part of the investigation into his chronic back pain, a contrast-enhanced CT scan of the abdomen and pelvis is performed. An axial view from the scan is shown. Based on the clinical presentation and the findings demonstrated in the provided image, which of the following is the MOST appropriate next step in management?

A. Refer urgently to a vascular surgeon for consideration of immediate endovascular repair.
B. Initiate a program of regular surveillance imaging with ultrasound and aggressively manage cardiovascular risk factors.
C. Reassure the patient that the finding is incidental and benign, and focus solely on managing his chronic back pain.
D. Arrange for immediate admission to hospital for observation and further investigation.
E. Schedule a repeat CT scan with contrast within 3 months to assess for rapid expansion.
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A 75-year-old obese man with a history of hypertension and chronic lower limb skin changes, swelling, tingling, and weakness presents with sudden onset inability to stand or move his legs, accompanied by a loss of sensation extending up to his waist. On examination, he has flaccid paralysis of both lower limbs, absent deep tendon reflexes in the legs, and a sensory level at the umbilicus. Which of the following is the most appropriate initial investigation?

A. Urgent MRI of the spine
B. Electromyography and nerve conduction studies
C. CT angiography of the aorta and iliac arteries
D. Lumbar puncture
E. Urgent CT scan of the spine
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department complaining of new onset left flank pain radiating to his groin. He reports a history of hypertension and hyperlipidemia, both managed with medications. He denies any recent trauma. His vital signs are stable: blood pressure 130/80 mmHg, heart rate 88 bpm, respiratory rate 16 breaths/min, and oxygen saturation 98% on room air. Physical examination reveals mild tenderness to palpation in the left flank, but no guarding or rebound tenderness. Peripheral pulses are normal and symmetric. A contrast-enhanced CT scan of the abdomen and pelvis is performed, the axial view is shown. Given the clinical context and the findings on the image, which of the following is the MOST appropriate next step in management?

A. Referral to vascular surgery for elective repair
B. Order a renal ultrasound to evaluate for hydronephrosis
C. Prescribe analgesics and schedule a repeat CT scan in 6 months
D. Start oral antibiotics for suspected pyelonephritis
E. Initiate intravenous heparin and consult vascular surgery for urgent repair
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A 45-year-old man presents to the emergency department with sudden onset of severe abdominal pain radiating to the back. He is a smoker and has a history of hypertension. On examination, he is diaphoretic, with a heart rate of 120 bpm and blood pressure of 90/60 mmHg. Abdominal examination reveals a pulsatile mass in the midline. What is the most likely diagnosis?

A. Acute pancreatitis
B. Ruptured abdominal aortic aneurysm
C. Acute mesenteric ischemia
D. Perforated peptic ulcer
E. Renal colic
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A 58-year-old man with a history of hypertension and left ventricular systolic dysfunction (LVSD) is being treated with an ACE inhibitor. His blood pressure is well-controlled, but he develops a persistent, dry cough that is affecting his sleep and quality of life. What is the most appropriate next step in management?

A. Add a cough suppressant
B. Switch to an angiotensin II receptor blocker (ARB)
C. Add a diuretic
D. Discontinue the ACE inhibitor and start a beta-blocker
E. Reduce the dose of the ACE inhibitor
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A 70-year-old man with a history of hypertension and hyperlipidemia presents to the emergency department with sudden onset, severe chest pain radiating to his back. He is diaphoretic and anxious. His blood pressure is 90/60 mmHg. Which of the following is the most likely diagnosis?

A. Esophageal rupture
B. Pulmonary embolism
C. Acute myocardial infarction
D. Pericarditis
E. Aortic dissection
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 62-year-old woman presents to the emergency department with a 2-day history of right upper quadrant abdominal pain, nausea, and vomiting. She reports that the pain started gradually but has become increasingly severe and constant. She denies any fever or chills. Her past medical history is significant for hypertension and hyperlipidemia, both well-controlled with medications. On physical examination, she is afebrile, with a heart rate of 92 bpm, blood pressure of 140/85 mmHg, and an oxygen saturation of 98% on room air. Abdominal examination reveals marked tenderness to palpation in the right upper quadrant with guarding. Murphy's sign is positive. The provided image was obtained. Which of the following is the MOST appropriate next step in the management of this patient?

A. Initiate intravenous antibiotics and observe
B. Perform an endoscopic retrograde cholangiopancreatography (ERCP)
C. Order a hepatobiliary iminodiacetic acid (HIDA) scan
D. Administer oral analgesics and discharge with outpatient follow-up
E. Surgical consultation for cholecystectomy
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 62-year-old man presents to his GP reporting a swelling in his right groin that has been present for approximately 18 months. He describes it as intermittent, appearing when he stands or strains, and disappearing when he lies down. He occasionally experiences a mild, dull ache in the area, but denies any severe pain, nausea, vomiting, or change in bowel habits. His past medical history includes hypertension controlled with medication. On examination, vital signs are stable, and the finding shown in the image is noted. It is easily reducible. Considering the patient's history, the absence of acute symptoms, and the physical examination finding depicted, what is the most appropriate next step in the management of this patient?

A. Order an urgent ultrasound scan of the groin to confirm the diagnosis.
B. Immediate referral to the emergency department for urgent surgical exploration.
C. Recommend the use of a supportive truss.
D. Prescribe simple analgesia and advise watchful waiting with regular review.
E. Referral for elective surgical repair.
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A 68-year-old woman is admitted to the hospital with confusion and muscle weakness. Her medications include hydrochlorothiazide for hypertension. Initial laboratory results show: Sodium 120 mmol/L (Normal: 135-145 mmol/L), Potassium 3.8 mmol/L (Normal: 3.5-5.0 mmol/L), Chloride 90 mmol/L (Normal: 95-105 mmol/L). What is the most likely cause of her hyponatremia?

A. Hyperglycemia
B. Thiazide-induced SIADH
C. Primary polydipsia
D. Renal failure
E. Adrenal insufficiency
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A 68-year-old man with a history of poorly controlled type 2 diabetes, hypertension, and chronic kidney disease (stage 3) presents to the emergency department with severe abdominal pain and vomiting. On examination, he has a distended abdomen with diffuse tenderness and guarding. His vital signs show a blood pressure of 90/60 mmHg, heart rate of 110 bpm, and a temperature of 38.5°C. Laboratory tests reveal leukocytosis, elevated serum lactate, and worsening renal function. A CT scan of the abdomen shows pneumoperitoneum and free fluid, suggesting perforated viscus. What is the most appropriate next step in the management of this patient?

A. Immediate exploratory laparotomy
B. Administer intravenous fluids and reassess in 2 hours
C. Initiate broad-spectrum antibiotics and observe
D. Consult nephrology for dialysis before surgery
E. Perform a diagnostic laparoscopy
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A patient is on metformin 1g BD, with a blood pressure of 135/85 mmHg, HbA1c of 8.5%, no history of cardiovascular disease, fasting blood sugar of 9 mmol/L, and an albumin/creatinine ratio of 500. Which drug should be added to their treatment regimen?

A. Pioglitazone
B. Ramipril
C. Sitagliptin
D. Gliclazide
E. Insulin
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A 72-year-old man with a history of hypertension, type 2 diabetes, and chronic kidney disease (CKD) presents to his general practitioner for a routine check-up. His current medications include metformin, insulin, amlodipine, and aspirin. His blood pressure today is 150/90 mmHg. Laboratory results show a serum creatinine of 2.5 mg/dL (221 micromol/L) and a potassium level of 5.4 mEq/L. The GP decides to add an ACE inhibitor to his treatment regimen to help manage his blood pressure and provide renal protection. One week later, the patient returns complaining of fatigue and muscle weakness. Repeat laboratory tests reveal a serum creatinine of 3.1 mg/dL (274 micromol/L) and a potassium level of 6.2 mEq/L. Which of the following is the most appropriate next step in managing this patient?

A. Add a potassium-binding resin (e.g., sodium polystyrene sulfonate) and continue the ACE inhibitor.
B. Prescribe a loop diuretic to counteract the hyperkalemia and continue the ACE inhibitor.
C. Refer the patient to a nephrologist for urgent dialysis.
D. Reduce the dose of the ACE inhibitor by 50% and recheck renal function and potassium levels in one week.
E. Discontinue the ACE inhibitor and monitor renal function and potassium levels.
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension and hyperlipidemia presents to the emergency department with a sudden onset of left-sided hemianopia and mild right-sided weakness. Her symptoms began approximately 4 hours prior to arrival. Initial neurological examination reveals intact language function and no cognitive deficits. A CT angiogram was performed, followed by endovascular coiling. The provided image shows a post-operative angiogram. Despite the intervention, the patient's hemianopia persists, and her weakness has slightly worsened. What is the MOST appropriate next step in the management of this patient?

A. Administer intravenous thrombolysis with alteplase
B. Prescribe a course of high-dose corticosteroids to reduce cerebral edema
C. Repeat angiography to assess for recanalization or further aneurysm growth
D. Start the patient on nimodipine to prevent vasospasm
E. Initiate dual antiplatelet therapy with aspirin and clopidogrel
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A 62-year-old woman presents to the emergency department with confusion and lethargy. Her family reports she has been increasingly forgetful over the past week and has had a decreased appetite. She has a history of type 2 diabetes mellitus and hypertension, for which she takes metformin and lisinopril. On examination, she is disoriented to time and place, with dry mucous membranes and decreased skin turgor. Her blood pressure is 100/60 mmHg, heart rate is 110 bpm, and temperature is 37.2°C. Laboratory tests reveal a serum sodium level of 118 mmol/L, serum osmolality of 260 mOsm/kg, and urine osmolality of 500 mOsm/kg. Which of the following is the most appropriate initial management for this patient?

A. Furosemide administration
B. Normal saline infusion
C. Hypertonic saline infusion
D. Fluid restriction
E. Demeclocycline administration
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension and hyperlipidemia presented to the emergency department with a sudden onset of left-sided hemianopia and mild right-sided weakness. Her symptoms began approximately 4 hours prior to arrival. Initial neurological examination revealed a left homonymous hemianopia, mild right hemiparesis (4/5 strength), and intact sensation. A CT angiogram was performed, identifying a cerebral aneurysm, and the patient subsequently underwent endovascular coiling. The provided image was obtained immediately following the procedure. Despite the intervention, the patient's left homonymous hemianopia persists, and her right hemiparesis has not improved. Considering the findings on the post-procedure imaging in the context of her ongoing neurological deficits, which of the following is the MOST appropriate immediate management step?

A. Administer intravenous thrombolysis given the persistent neurological deficits.
B. Perform an urgent brain MRI with diffusion-weighted imaging to assess for extent of infarction.
C. Initiate or optimise dual antiplatelet therapy to mitigate the risk of thromboembolism from the residual sac.
D. Continue current medical management and arrange for routine outpatient follow-up angiography in 3-6 months.
E. Arrange for urgent repeat endovascular coiling of the aneurysm to achieve complete occlusion.
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A 67-year-old man presents to the emergency department with sudden onset of severe headache, nausea, and vomiting. He has a history of hypertension and is currently on amlodipine. On examination, he is drowsy but arousable, with a blood pressure of 210/120 mmHg and a heart rate of 90 bpm. Neurological examination reveals a left-sided hemiparesis and a right-sided facial droop. A CT scan of the head shows a hyperdense lesion in the right basal ganglia with surrounding edema. Which of the following is the most appropriate initial management step?

A. Intravenous labetalol to lower blood pressure
B. Oral aspirin to prevent further clot formation
C. Immediate surgical evacuation of the hematoma
D. Intravenous alteplase for thrombolysis
E. Intravenous mannitol to reduce intracranial pressure
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A 55-year-old non-smoker with no known comorbidities has a consistent office BP of 155/98 mmHg. His 10-year CVD risk is calculated as low. According to Australian guidelines, what is the most appropriate initial management?

A. Recommend lifestyle modifications and review in 3-6 months
B. Investigate for secondary causes of hypertension
C. Initiate single antihypertensive therapy
D. Refer for ambulatory blood pressure monitoring
E. Initiate dual antihypertensive therapy
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A 45-year-old man presents to the emergency department with sudden onset of severe headache, nausea, and vomiting. He describes the headache as the worst he has ever experienced. He has a history of hypertension but is otherwise healthy. On examination, he is alert but in distress due to the headache. His blood pressure is 180/110 mmHg, heart rate is 90 bpm, and he has no focal neurological deficits. A CT scan of the head shows no acute intracranial hemorrhage. What is the next best step in management?

A. Administer analgesics and observe
B. Repeat CT scan with contrast
C. MRI of the brain
D. Lumbar puncture
E. Start antihypertensive therapy
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old man with a history of hypertension and hyperlipidemia presents for a routine health check. He is asymptomatic. A contrast-enhanced CT abdomen is performed, axial view shown. Besides optimizing medical management, what is the MOST appropriate next step?

A. Referral for immediate surgical repair
B. Prescribe a statin
C. Initiate aspirin therapy
D. Repeat imaging in 6-12 months
E. Order a D-dimer
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A 60-year-old man presents to the emergency department with sudden onset of severe chest pain that radiates to his back. He describes the pain as tearing in nature. His blood pressure is 180/100 mmHg in the right arm and 160/90 mmHg in the left arm. On examination, there is a new diastolic murmur heard best at the right sternal border. What is the most appropriate next step in management?

A. Administer sublingual nitroglycerin
B. Perform an ECG
C. Order a CT angiography of the chest
D. Administer aspirin
E. Start intravenous heparin
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old man presents with a 4-month history of bilateral breast enlargement and tenderness. He denies weight loss, fever, or changes in bowel habit. His medical history includes hypertension managed with amlodipine. On examination, vital signs are stable. The physical findings are demonstrated in the image. There is no palpable testicular mass. Given the clinical presentation and the findings shown, which of the following investigations is the most appropriate initial step to determine the underlying cause?

A. Mammography of both breasts
B. Fine needle aspiration of the breast tissue
C. Serum testosterone, oestradiol, LH, FSH, prolactin, and hCG
D. Trial of tamoxifen
E. Liver function tests and renal function tests
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old male presents to the ED with increasing shortness of breath and epigastric pain, especially when lying down. He has a history of GORD, hypertension and COPD. His vitals are stable. An X-ray is performed. What is the MOST appropriate next step in management?

A. Administer intravenous antibiotics for possible aspiration pneumonia
B. Prescribe a short course of oral corticosteroids for COPD exacerbation
C. Order a barium swallow study to assess esophageal motility
D. Initiate a proton pump inhibitor and schedule an upper endoscopy
E. Perform a diagnostic thoracentesis to rule out pleural effusion
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A 52-year-old woman presents to her general practitioner with fatigue, increased thirst, and frequent urination over the past three months. She has a history of hypertension and hyperlipidemia, for which she takes lisinopril and atorvastatin. Her BMI is 32 kg/m². On examination, her blood pressure is 140/85 mmHg, and her heart rate is 78 bpm. Laboratory tests reveal a fasting plasma glucose of 8.5 mmol/L and an HbA1c of 7.2%. She is diagnosed with type 2 diabetes mellitus. Which of the following is the most appropriate initial management step for this patient according to Australian guidelines?

A. Lifestyle modification including diet and exercise
B. Commencement of insulin therapy
C. Initiation of metformin therapy
D. Referral to an endocrinologist
E. Addition of a sulfonylurea
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A 45-year-old man presents to the clinic with a 3-month history of fatigue, weight loss, and abdominal pain. He has a history of type 2 diabetes and hypertension. On examination, he has a palpable mass in the left upper quadrant of the abdomen. Laboratory tests reveal anemia and elevated serum lactate dehydrogenase (LDH). A CT scan of the abdomen shows splenomegaly and multiple hypodense lesions in the spleen. What is the most likely diagnosis?

A. Splenic lymphoma
B. Renal cell carcinoma with splenic metastasis
C. Chronic pancreatitis
D. Infectious mononucleosis
E. Portal hypertension
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A 65-year-old man with a history of hypertension and ischemic heart disease presents to the emergency department with worsening shortness of breath, orthopnea, and peripheral edema. On examination, he has elevated jugular venous pressure, bilateral basal crackles, and pitting edema in the lower limbs. An echocardiogram shows an ejection fraction of 35%. What is the most appropriate initial management step for this patient?

A. Initiate digoxin therapy
B. Perform coronary angiography
C. Start oral beta-blockers
D. Administer intravenous furosemide
E. Prescribe oral ACE inhibitors
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A 68-year-old man with a history of hypertension, type 2 diabetes, and stable angina is scheduled for elective hernia repair surgery. He is currently on aspirin, metformin, lisinopril, and atorvastatin. His last angina episode was over a year ago, and he has no history of myocardial infarction. What is the most appropriate preoperative management step to minimize his cardiovascular risk during surgery?

A. Discontinue aspirin therapy one week before surgery
B. Increase the dose of atorvastatin
C. Continue aspirin therapy
D. Order a preoperative stress test
E. Start beta-blocker therapy
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension and hyperlipidemia presents to the emergency department with a sudden onset of left-sided hemianopia and mild right-sided weakness. Her symptoms began approximately 4 hours prior to arrival. Initial neurological examination reveals intact language function and no cognitive deficits. A CT angiogram was performed, followed by endovascular coiling. The provided image shows a post-operative angiogram. Despite the intervention, the patient's hemianopia persists, and her weakness has slightly worsened. What is the MOST appropriate next step in the management of this patient?

A. Prescribe a course of high-dose corticosteroids to reduce peri-aneurysmal edema
B. Order an MRI of the brain to evaluate for ischemic changes
C. Initiate dual antiplatelet therapy with aspirin and clopidogrel
D. Repeat angiography to assess for recanalization or further aneurysm growth
E. Administer intravenous thrombolysis with alteplase
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A 68-year-old man with a history of hypertension and coronary artery disease presents to the emergency department with worsening shortness of breath and fatigue over the past week. On examination, he has elevated jugular venous pressure, bilateral lung crackles, and peripheral edema. An echocardiogram reveals reduced ejection fraction and dilated ventricles. Which of the following best explains the pathophysiological mechanism leading to his symptoms?

A. Increased peripheral resistance leading to left ventricular hypertrophy
B. Decreased venous return causing systemic hypotension
C. Enhanced myocardial contractility resulting in fluid retention
D. Decreased cardiac output leading to activation of the renin-angiotensin-aldosterone system
E. Increased cardiac output causing pulmonary congestion
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A 45-year-old man with a history of hypertension presents to the emergency department with palpitations and lightheadedness. His ECG shows a regular narrow-complex tachycardia at a rate of 180 bpm. There are no visible P waves, and the QRS duration is 0.08 seconds. He is hemodynamically stable. Which of the following is the most appropriate initial management?

A. Synchronized cardioversion
B. Observation without intervention
C. Intravenous adenosine
D. Vagal maneuvers
E. Intravenous metoprolol
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A 62-year-old woman with a 15-year history of type 2 diabetes mellitus presents to her general practitioner with complaints of worsening vision over the past six months. She also reports intermittent tingling and numbness in her feet, which has been progressively worsening. Her diabetes has been poorly controlled, with recent HbA1c levels consistently above 9%. She has a history of hypertension and hyperlipidemia, both of which are managed with medication. On examination, her blood pressure is 140/85 mmHg, and her BMI is 32 kg/m². Fundoscopic examination reveals microaneurysms and cotton wool spots. Urinalysis shows microalbuminuria. Which of the following interventions is most likely to address the underlying pathophysiological mechanism of her visual symptoms?

A. Optimizing glycemic control
B. Prescribing an ACE inhibitor
C. Recommending regular exercise
D. Starting a statin
E. Initiating aspirin therapy
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A 72-year-old man presents to the emergency department with confusion and difficulty walking. His family reports that he has been increasingly forgetful over the past few months and has had several falls. He has a history of hypertension and hyperlipidemia, for which he takes lisinopril and atorvastatin. On examination, he is disoriented to time and place, with a blood pressure of 140/85 mmHg, heart rate of 78 bpm, and a wide-based gait. Neurological examination reveals brisk reflexes and a positive Romberg sign. A CT scan of the head shows mild cortical atrophy but no acute lesions. Which of the following is the most likely diagnosis?

A. Vascular dementia
B. Normal pressure hydrocephalus
C. Parkinson's disease
D. Alzheimer's disease
E. Subdural hematoma
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A 72-year-old man with a history of hypertension and atrial fibrillation presents to the emergency department with worsening shortness of breath and fatigue over the past two weeks. He reports occasional palpitations but denies chest pain or syncope. On examination, his blood pressure is 110/70 mmHg, heart rate is 130 bpm (irregularly irregular), respiratory rate is 22 breaths per minute, and oxygen saturation is 94% on room air. Jugular venous pressure is elevated, and there are bilateral lung crackles. An ECG shows atrial fibrillation with a rapid ventricular response. An echocardiogram reveals moderate mitral regurgitation and left atrial enlargement. Which of the following is the most appropriate initial management step?

A. Initiation of antiarrhythmic therapy with amiodarone
B. Rate control with intravenous diltiazem
C. Immediate electrical cardioversion
D. Initiation of oral anticoagulation
E. Referral for mitral valve surgery
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old male presents to the ED with increasing shortness of breath and epigastric pain, especially when lying down. He has a history of GORD, hypertension and COPD. His vitals are stable. An X-ray is performed. What is the MOST likely underlying cause of his presentation?

A. Gastric malignancy
B. Esophageal dysmotility
C. Reduced lower esophageal sphincter tone
D. Aortic aneurysm
E. Pneumonia
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A 70-year-old woman with a history of hypertension presents with fatigue, shortness of breath, and bilateral leg swelling. Echocardiography shows an ejection fraction of 30%. What is the most appropriate first-line treatment?

A. Calcium channel blocker
B. Nitrate therapy
C. ACE inhibitor and beta-blocker
D. Digoxin
E. Diuretic therapy alone
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A 55-year-old male with a history of hypertension presents for a routine check-up. His blood pressure is consistently measured at 150/95 mmHg despite lifestyle modifications. According to Australian guidelines, what is the most appropriate next step in managing his hypertension?

A. Prescribe a diuretic
B. Increase lifestyle modifications
C. Refer to a cardiologist
D. Start a beta-blocker
E. Initiate an ACE inhibitor
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A 72-year-old man with a history of hypertension and type 2 diabetes mellitus is being managed with lisinopril. He presents to the emergency department complaining of lip swelling and difficulty breathing. On examination, his tongue appears swollen. What is the most appropriate immediate management?

A. Administer intramuscular epinephrine
B. Administer intravenous corticosteroids
C. Administer nebulized bronchodilators
D. Administer intravenous antihistamines
E. Observe and monitor vital signs
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A 52-year-old woman presents to her general practitioner with fatigue, increased thirst, and frequent urination over the past three months. She has a history of hypertension and hyperlipidemia, managed with lisinopril and atorvastatin. Her BMI is 32 kg/m². On examination, her blood pressure is 140/85 mmHg, and her heart rate is 78 bpm. Laboratory tests reveal a fasting plasma glucose of 8.5 mmol/L and an HbA1c of 7.2%. She is concerned about her risk of complications and asks about the best initial management strategy. Considering Australian guidelines, what is the most appropriate next step in managing her condition?

A. Initiate metformin therapy
B. Advise lifestyle modifications only
C. Prescribe a sulfonylurea
D. Refer to an endocrinologist immediately
E. Start insulin therapy
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A 55-year-old man with a history of hypertension and stable angina is prescribed a new medication. He reports experiencing a persistent dry cough since starting the medication. Which drug is most likely responsible for this side effect?

A. Amlodipine
B. Losartan
C. Enalapril
D. Hydrochlorothiazide
E. Atenolol
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A 72-year-old man with a history of hypertension, hyperlipidemia, and type 2 diabetes mellitus presents to the emergency department complaining of exertional chest pain that has been increasing in frequency and severity over the past month. He describes the pain as a pressure-like sensation in the center of his chest, radiating to his left arm, and associated with shortness of breath. The pain typically occurs after walking two blocks and resolves with rest. He denies any recent changes in his medications or lifestyle. On examination, his blood pressure is 150/90 mmHg, heart rate is 78 bpm, and oxygen saturation is 96% on room air. An ECG shows normal sinus rhythm with no acute ST-segment changes. Troponin levels are within normal limits. Which of the following is the MOST appropriate next step in the management of this patient?

A. Stress echocardiography
B. Discharge home with instructions to follow up with his general practitioner
C. Initiate a trial of increased anti-anginal medications and lifestyle modifications
D. Coronary angiography
E. CT angiography of the chest
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A 45-year-old male presents to the emergency department with severe chest pain radiating to his left arm, shortness of breath, and diaphoresis. He has a history of hypertension and hyperlipidemia. On examination, he is diaphoretic, and his blood pressure is 90/60 mmHg. An ECG shows ST-segment elevation in leads II, III, and aVF. What is the most appropriate initial management for this patient?

A. Administer intravenous fluids to address hypotension
B. Administer beta-blockers to reduce myocardial oxygen demand
C. Administer morphine for pain management
D. Administer aspirin and initiate reperfusion therapy
E. Administer nitroglycerin for chest pain relief
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A 68-year-old man with a history of smoking and hypertension presents with intermittent claudication in his right leg. Ankle-brachial index (ABI) is 0.6 on the right and 0.9 on the left. He has been on a supervised exercise program and optimal medical therapy for 6 months with no improvement in symptoms. What is the most appropriate next step in management?

A. Continue with the current exercise program and medical therapy
B. Consideration for revascularization with angioplasty or bypass surgery
C. Start a trial of cilostazol
D. Increase the dose of his antihypertensive medication
E. Refer for a vascular ultrasound to reassess the ABI
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A 45-year-old woman presents to the emergency department with sudden onset of severe headache, described as the worst headache of her life. She also reports nausea and photophobia. Her past medical history is significant for hypertension, which is poorly controlled. On examination, she is alert but in distress, with a blood pressure of 180/110 mmHg, heart rate of 90 bpm, and temperature of 37°C. Neurological examination reveals neck stiffness but no focal neurological deficits. A CT scan of the head is performed and shows no acute intracranial hemorrhage. What is the next best step in management?

A. Lumbar puncture
B. Start intravenous labetalol
C. MRI of the brain
D. Administer sumatriptan
E. Repeat CT scan with contrast
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A 67-year-old man presents to the emergency department with sudden onset of severe chest pain radiating to his back. He describes the pain as tearing in nature. His blood pressure is 180/100 mmHg in the right arm and 160/90 mmHg in the left arm. He has a history of hypertension and is a smoker. An ECG shows no acute ischemic changes. What is the most appropriate next step in the management of this patient?

A. Start intravenous heparin
B. Administer sublingual nitroglycerin
C. Administer aspirin and clopidogrel
D. Order a CT angiography of the chest
E. Perform an urgent coronary angiogram
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A 70-year-old man with a history of hypertension and heart failure is being managed with an ACE inhibitor. He presents to the emergency department complaining of dizziness, especially when standing up. His blood pressure is 90/60 mmHg, and his other vital signs are stable. Which of the following is the most appropriate initial step in managing this patient?

A. Order an ECG to rule out cardiac arrhythmia
B. Prescribe compression stockings
C. Review and potentially reduce the dose of the ACE inhibitor
D. Administer an intravenous bolus of normal saline
E. Start fludrocortisone
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A 55-year-old man with a history of hypertension presents for a routine check-up. His blood pressure is consistently measured at 160/95 mmHg despite lifestyle modifications. He is currently on perindopril 5 mg daily. According to Australian guidelines, what is the most appropriate next step in managing his hypertension?

A. Switch to losartan
B. Refer for renal artery imaging
C. Add hydrochlorothiazide
D. Add amlodipine
E. Increase perindopril to 10 mg daily
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A 45-year-old man presents to the emergency department with sudden onset of severe chest pain radiating to his back. He describes the pain as tearing in nature. He has a history of hypertension and is a smoker. On examination, his blood pressure is 180/110 mmHg in the right arm and 160/100 mmHg in the left arm. His heart rate is 110 bpm, and he has a new diastolic murmur. An ECG shows left ventricular hypertrophy but no ischemic changes. What is the most appropriate next step in management?

A. Immediate thrombolysis
B. Chest X-ray
C. Echocardiography
D. Coronary angiography
E. CT angiography of the chest
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old man presents with the condition shown. He reports taking spironolactone for hypertension. What is the MOST appropriate next step?

A. Refer to endocrinology for hormonal evaluation
B. Initiate treatment with tamoxifen
C. Order a mammogram to rule out malignancy
D. Review and potentially adjust his antihypertensive medication
E. Reassure the patient that this is a normal age-related change
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