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hypertension

Practice targeted AMC-style multiple-choice questions on hypertension.

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A 70-year-old man presents to the emergency department with sudden onset of severe headache, nausea, and vomiting. He has a history of hypertension and is currently on antihypertensive medication. On examination, he is drowsy and has a blood pressure of 180/110 mmHg. A CT scan of the brain shows a hyperdense area in the right basal ganglia. What is the most likely diagnosis?

A. Intracerebral hemorrhage
B. Ischemic stroke
C. Migraine with aura
D. Transient ischemic attack
E. Subarachnoid hemorrhage
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A 65-year-old man with hypertension is started on a medication that blocks the angiotensin-converting enzyme (ACE). What is the most common side effect of this class of drugs?

A. Hyperkalemia
B. Acute kidney injury
C. Angioedema
D. Hypotension
E. Dry cough
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old man with a history of smoking, hypertension, and dyslipidaemia presents for investigation of intermittent flank pain. Physical examination is unremarkable. Routine blood tests are normal. A CT scan of the abdomen is performed. Considering the findings demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. Surveillance with abdominal ultrasound in 12 months
B. Urgent referral for surgical assessment and repair planning
C. Referral for immediate endovascular aneurysm repair
D. No specific follow-up imaging required, focus on risk factor modification
E. Repeat CT scan of the abdomen in 3 months
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A 67-year-old man with a history of type 2 diabetes mellitus and hypertension presents to the emergency department with sudden onset of right-sided weakness and slurred speech that began 2 hours ago. He has no history of atrial fibrillation or previous strokes. On examination, his blood pressure is 180/95 mmHg, heart rate is 88 bpm, and he is afebrile. Neurological examination reveals right-sided hemiparesis and expressive aphasia. A non-contrast CT scan of the head shows no evidence of hemorrhage. Which of the following is the most appropriate next step in the management of this patient?

A. Perform a CT angiogram of the head and neck
B. Administer intravenous labetalol to lower blood pressure
C. Intravenous thrombolysis with alteplase
D. Refer for urgent carotid endarterectomy
E. Start aspirin therapy
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A 72-year-old man with a history of chronic kidney disease stage 4, hypertension, and type 2 diabetes presents to the emergency department with confusion and lethargy. His family reports that he has been increasingly drowsy over the past two days. On examination, he is disoriented to time and place, with a blood pressure of 150/90 mmHg, heart rate of 88 bpm, respiratory rate of 20 breaths per minute, and temperature of 36.5°C. Laboratory tests reveal: sodium 130 mmol/L, potassium 5.8 mmol/L, bicarbonate 18 mmol/L, urea 25 mmol/L, creatinine 450 µmol/L, and glucose 8 mmol/L. An ECG shows peaked T waves. What is the most appropriate immediate management step?

A. Administer oral sodium polystyrene sulfonate
B. Administer intravenous calcium gluconate
C. Initiate hemodialysis
D. Start intravenous insulin and glucose
E. Administer intravenous sodium bicarbonate
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A 68-year-old woman with a history of hypertension and heart failure is being treated with an ACE inhibitor. Her recent blood tests show a potassium level of 5.8 mmol/L. Which of the following is the most appropriate initial step in managing her hyperkalemia?

A. Prescribe a loop diuretic such as furosemide
B. Administer intravenous calcium gluconate
C. Immediately commence haemodialysis
D. Review and potentially reduce or discontinue the ACE inhibitor
E. Administer intravenous insulin and glucose
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male presents to his general practitioner complaining of mild, chronic lower back pain that has been present for several months. He describes the pain as a dull ache, worse with prolonged standing. He has a significant past medical history including hypertension, hyperlipidemia, and a 50-pack-year smoking history, all of which are currently managed with medications. He denies any acute abdominal pain, pulsatile sensation, or leg symptoms. On physical examination, his vital signs are stable: blood pressure 135/85 mmHg, heart rate 72 bpm, respiratory rate 14 breaths/min, and oxygen saturation 99% on room air. Abdominal examination is soft, non-tender, with no palpable masses. Peripheral pulses are symmetric and strong. As part of the investigation into his chronic back pain, a contrast-enhanced CT scan of the abdomen and pelvis is performed. An axial view from the scan is shown. Based on the clinical presentation and the findings demonstrated in the provided image, which of the following is the MOST appropriate next step in management?

A. Refer urgently to a vascular surgeon for consideration of immediate endovascular repair.
B. Initiate a program of regular surveillance imaging with ultrasound and aggressively manage cardiovascular risk factors.
C. Reassure the patient that the finding is incidental and benign, and focus solely on managing his chronic back pain.
D. Arrange for immediate admission to hospital for observation and further investigation.
E. Schedule a repeat CT scan with contrast within 3 months to assess for rapid expansion.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male with a history of hypertension and hyperlipidemia presents for a routine follow-up. He is asymptomatic. A contrast-enhanced CT scan of the abdomen was performed as part of a screening protocol. An axial view is shown. What is the MOST appropriate next step?

A. Start aspirin therapy
B. Measure ankle-brachial index
C. Initiate statin therapy
D. Surgical repair
E. Repeat imaging in 6-12 months
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents to his general practitioner for a routine check-up. He reports a history of hypertension, hyperlipidemia, and a 40-pack-year smoking history. He denies any abdominal pain, back pain, or lower extremity claudication. On physical examination, his vital signs are within normal limits. Auscultation of the abdomen is unremarkable, and peripheral pulses are palpable and symmetric. As part of his cardiovascular risk assessment, a contrast-enhanced CT scan of the abdomen and pelvis is performed. An axial view from the scan is shown. Based on the image and the patient's clinical presentation, which of the following is the MOST appropriate next step in management?

A. Prescribe a beta-blocker to reduce blood pressure and heart rate
B. Schedule a repeat CT scan in 6-12 months to monitor aneurysm size
C. Refer to vascular surgery for elective repair
D. Order an ultrasound of the abdomen to further evaluate the aorta
E. Initiate statin therapy and lifestyle modifications
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department complaining of new onset left flank pain radiating to his groin. He reports a history of hypertension and hyperlipidemia, both managed with medications. He denies any recent trauma. His vital signs are stable: blood pressure 130/80 mmHg, heart rate 88 bpm, respiratory rate 16 breaths/min, and oxygen saturation 98% on room air. Physical examination reveals mild tenderness to palpation in the left flank, but no guarding or rebound tenderness. Peripheral pulses are normal and symmetric. A contrast-enhanced CT scan of the abdomen and pelvis is performed, the axial view is shown. Given the clinical context and the findings on the image, which of the following is the MOST appropriate next step in management?

A. Referral to vascular surgery for elective repair
B. Order a renal ultrasound to evaluate for hydronephrosis
C. Prescribe analgesics and schedule a repeat CT scan in 6 months
D. Start oral antibiotics for suspected pyelonephritis
E. Initiate intravenous heparin and consult vascular surgery for urgent repair
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A 45-year-old man presents to the emergency department with sudden onset of severe abdominal pain radiating to the back. He is a smoker and has a history of hypertension. On examination, he is diaphoretic, with a heart rate of 120 bpm and blood pressure of 90/60 mmHg. Abdominal examination reveals a pulsatile mass in the midline. What is the most likely diagnosis?

A. Acute pancreatitis
B. Ruptured abdominal aortic aneurysm
C. Acute mesenteric ischemia
D. Perforated peptic ulcer
E. Renal colic
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A 58-year-old man with a history of hypertension and left ventricular systolic dysfunction (LVSD) is being treated with an ACE inhibitor. His blood pressure is well-controlled, but he develops a persistent, dry cough that is affecting his sleep and quality of life. What is the most appropriate next step in management?

A. Add a cough suppressant
B. Switch to an angiotensin II receptor blocker (ARB)
C. Add a diuretic
D. Discontinue the ACE inhibitor and start a beta-blocker
E. Reduce the dose of the ACE inhibitor
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for routine follow-up. He is asymptomatic. His past medical history includes hypertension and hyperlipidemia, both well-controlled with medication. Review the provided image. What is the most appropriate next step in management?

A. Prescribe a statin
B. Repeat CT scan in 3 months
C. Referral for immediate surgical repair
D. Annual ultrasound surveillance
E. Initiate beta-blocker therapy
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A 70-year-old man with a history of hypertension and hyperlipidemia presents to the emergency department with sudden onset, severe chest pain radiating to his back. He is diaphoretic and anxious. His blood pressure is 90/60 mmHg. Which of the following is the most likely diagnosis?

A. Esophageal rupture
B. Pulmonary embolism
C. Acute myocardial infarction
D. Pericarditis
E. Aortic dissection
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 62-year-old woman presents to the emergency department with a 2-day history of right upper quadrant abdominal pain, nausea, and vomiting. She reports that the pain started gradually but has become increasingly severe and constant. She denies any fever or chills. Her past medical history is significant for hypertension and hyperlipidemia, both well-controlled with medications. On physical examination, she is afebrile, with a heart rate of 92 bpm, blood pressure of 140/85 mmHg, and an oxygen saturation of 98% on room air. Abdominal examination reveals marked tenderness to palpation in the right upper quadrant with guarding. Murphy's sign is positive. The provided image was obtained. Which of the following is the MOST appropriate next step in the management of this patient?

A. Initiate intravenous antibiotics and observe
B. Perform an endoscopic retrograde cholangiopancreatography (ERCP)
C. Order a hepatobiliary iminodiacetic acid (HIDA) scan
D. Administer oral analgesics and discharge with outpatient follow-up
E. Surgical consultation for cholecystectomy
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A 72-year-old man with a history of type 2 diabetes mellitus, hypertension, and chronic kidney disease (stage 3) presents with a 2-week history of exertional dyspnea and fatigue. He reports no chest pain but has noticed occasional palpitations. On examination, his blood pressure is 150/90 mmHg, heart rate is 110 bpm (irregularly irregular), respiratory rate is 20 breaths per minute, and oxygen saturation is 94% on room air. Cardiovascular examination reveals a variable intensity S1, no S3 or S4, and a soft systolic murmur at the apex. Lung fields are clear. An ECG shows absent P waves and irregularly irregular QRS complexes. Which of the following is the most appropriate next step in management?

A. Start a beta-blocker for rate control
B. Administer intravenous digoxin
C. Perform immediate electrical cardioversion
D. Initiate anticoagulation therapy
E. Refer for urgent coronary angiography
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male with a history of hypertension and smoking undergoes a CT scan for investigation of chronic back pain. He denies any abdominal pain, pulsatile mass, or leg ischaemia. His blood pressure is 130/80 mmHg, pulse 72 bpm. The image provided is an axial view from this scan. Based on this finding, what is the most appropriate next step in his management?

A. Arrange for urgent surgical consultation.
B. No further follow-up is required.
C. Arrange for surveillance ultrasound in 12 months.
D. Schedule elective endovascular aneurysm repair (EVAR).
E. Repeat CT angiography in 6 months.
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A 68-year-old man with a history of poorly controlled type 2 diabetes, hypertension, and chronic kidney disease (stage 3) presents to the emergency department with severe abdominal pain and vomiting. On examination, he has a distended abdomen with diffuse tenderness and guarding. His vital signs show a blood pressure of 90/60 mmHg, heart rate of 110 bpm, and a temperature of 38.5°C. Laboratory tests reveal leukocytosis, elevated serum lactate, and worsening renal function. A CT scan of the abdomen shows pneumoperitoneum and free fluid, suggesting perforated viscus. What is the most appropriate next step in the management of this patient?

A. Immediate exploratory laparotomy
B. Administer intravenous fluids and reassess in 2 hours
C. Initiate broad-spectrum antibiotics and observe
D. Consult nephrology for dialysis before surgery
E. Perform a diagnostic laparoscopy
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension presents with a severe headache and altered mental status. Aneurysmal coiling was performed. The image shows a post-operative angiogram. 6 hours later, the patient's GCS decreases. What is the MOST likely cause?

A. Hydrocephalus
B. Post-operative delirium
C. Re-rupture of the aneurysm
D. Vasospasm
E. Cerebral salt wasting
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A 72-year-old man with a history of hypertension, type 2 diabetes, and chronic kidney disease (CKD) presents to his general practitioner for a routine check-up. His current medications include metformin, insulin, amlodipine, and aspirin. His blood pressure today is 150/90 mmHg. Laboratory results show a serum creatinine of 2.5 mg/dL (221 micromol/L) and a potassium level of 5.4 mEq/L. The GP decides to add an ACE inhibitor to his treatment regimen to help manage his blood pressure and provide renal protection. One week later, the patient returns complaining of fatigue and muscle weakness. Repeat laboratory tests reveal a serum creatinine of 3.1 mg/dL (274 micromol/L) and a potassium level of 6.2 mEq/L. Which of the following is the most appropriate next step in managing this patient?

A. Add a potassium-binding resin (e.g., sodium polystyrene sulfonate) and continue the ACE inhibitor.
B. Prescribe a loop diuretic to counteract the hyperkalemia and continue the ACE inhibitor.
C. Refer the patient to a nephrologist for urgent dialysis.
D. Reduce the dose of the ACE inhibitor by 50% and recheck renal function and potassium levels in one week.
E. Discontinue the ACE inhibitor and monitor renal function and potassium levels.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for a routine check-up. He has a history of smoking and hypertension, managed with lisinopril. He denies any abdominal pain, back pain, or lower extremity claudication. Physical exam is unremarkable. A contrast-enhanced CT scan of the abdomen is performed, the axial view is shown. What is the MOST appropriate next step in management?

A. Order a D-dimer to rule out acute aortic dissection
B. Referral to vascular surgery for elective repair
C. Initiate beta-blocker therapy to reduce wall stress
D. Repeat imaging in 6-12 months to monitor growth
E. Prescribe a statin to stabilize atherosclerotic plaques
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension and hyperlipidemia presented to the emergency department with a sudden onset of left-sided hemianopia and mild right-sided weakness. Her symptoms began approximately 4 hours prior to arrival. Initial neurological examination revealed a left homonymous hemianopia, mild right hemiparesis (4/5 strength), and intact sensation. A CT angiogram was performed, identifying a cerebral aneurysm, and the patient subsequently underwent endovascular coiling. The provided image was obtained immediately following the procedure. Despite the intervention, the patient's left homonymous hemianopia persists, and her right hemiparesis has not improved. Considering the findings on the post-procedure imaging in the context of her ongoing neurological deficits, which of the following is the MOST appropriate immediate management step?

A. Administer intravenous thrombolysis given the persistent neurological deficits.
B. Perform an urgent brain MRI with diffusion-weighted imaging to assess for extent of infarction.
C. Initiate or optimise dual antiplatelet therapy to mitigate the risk of thromboembolism from the residual sac.
D. Continue current medical management and arrange for routine outpatient follow-up angiography in 3-6 months.
E. Arrange for urgent repeat endovascular coiling of the aneurysm to achieve complete occlusion.
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A 45-year-old man presents to the emergency department with sudden onset of severe chest pain radiating to his back. He describes the pain as tearing in nature. He has a history of hypertension and is a smoker. On examination, his blood pressure is 180/110 mmHg in the right arm and 160/100 mmHg in the left arm. His heart rate is 110 bpm, and he has diminished pulses in the left radial artery. A chest X-ray shows a widened mediastinum. Which of the following is the most appropriate next step in management?

A. Immediate surgical consultation
B. CT angiography of the chest
C. Nitroglycerin infusion
D. Intravenous beta-blockers
E. Echocardiography
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A 55-year-old non-smoker with no known comorbidities has a consistent office BP of 155/98 mmHg. His 10-year CVD risk is calculated as low. According to Australian guidelines, what is the most appropriate initial management?

A. Recommend lifestyle modifications and review in 3-6 months
B. Investigate for secondary causes of hypertension
C. Initiate single antihypertensive therapy
D. Refer for ambulatory blood pressure monitoring
E. Initiate dual antihypertensive therapy
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A 45-year-old man presents to the emergency department with sudden onset of severe headache, nausea, and vomiting. He describes the headache as the worst he has ever experienced. He has a history of hypertension but is otherwise healthy. On examination, he is alert but in distress due to the headache. His blood pressure is 180/110 mmHg, heart rate is 90 bpm, and he has no focal neurological deficits. A CT scan of the head shows no acute intracranial hemorrhage. What is the next best step in management?

A. Administer analgesics and observe
B. Repeat CT scan with contrast
C. MRI of the brain
D. Lumbar puncture
E. Start antihypertensive therapy
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 58-year-old male presents to the emergency department complaining of right groin pain that started approximately 6 hours ago. He reports noticing a bulge in his groin for several months, which he could usually push back in. However, today he is unable to reduce it, and the pain has become progressively severe. He denies any fever, nausea, or vomiting. His past medical history includes hypertension and hyperlipidemia, both well-controlled with medications. On examination, his vital signs are stable: blood pressure 130/80 mmHg, heart rate 80 bpm, respiratory rate 16 bpm, and temperature 37.0°C. Abdominal examination is benign. Examination of the groin reveals the finding shown in the image. The area is tender to palpation. Which of the following is the MOST appropriate next step in the management of this patient?

A. Surgical consultation for emergent repair
B. Ultrasound of the groin to rule out testicular torsion
C. Prescription for a truss and referral to a general surgeon for elective repair
D. CT scan of the abdomen and pelvis with intravenous contrast
E. Trial of manual reduction with sedation and analgesia
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A 60-year-old man presents to the emergency department with sudden onset of severe chest pain that radiates to his back. He describes the pain as tearing in nature. His blood pressure is 180/100 mmHg in the right arm and 160/90 mmHg in the left arm. On examination, there is a new diastolic murmur heard best at the right sternal border. What is the most appropriate next step in management?

A. Administer sublingual nitroglycerin
B. Perform an ECG
C. Order a CT angiography of the chest
D. Administer aspirin
E. Start intravenous heparin
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old man presents with a 4-month history of bilateral breast enlargement and tenderness. He denies weight loss, fever, or changes in bowel habit. His medical history includes hypertension managed with amlodipine. On examination, vital signs are stable. The physical findings are demonstrated in the image. There is no palpable testicular mass. Given the clinical presentation and the findings shown, which of the following investigations is the most appropriate initial step to determine the underlying cause?

A. Mammography of both breasts
B. Fine needle aspiration of the breast tissue
C. Serum testosterone, oestradiol, LH, FSH, prolactin, and hCG
D. Trial of tamoxifen
E. Liver function tests and renal function tests
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A 62-year-old man presents to the emergency department with acute onset chest pain radiating to his left arm and jaw, accompanied by diaphoresis and nausea. He has a history of hypertension, type 2 diabetes mellitus, and hyperlipidemia. On examination, his blood pressure is 160/95 mmHg, heart rate is 95 bpm, respiratory rate is 20 breaths per minute, and oxygen saturation is 96% on room air. An ECG shows ST-segment elevation in leads II, III, and aVF. Initial troponin levels are elevated. He is given aspirin and clopidogrel in the emergency department. Which of the following is the most appropriate next step in management?

A. Urgent percutaneous coronary intervention (PCI)
B. Intravenous nitroglycerin
C. Coronary artery bypass grafting (CABG)
D. Intravenous thrombolysis
E. Beta-blocker administration
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old male presents to the ED with increasing shortness of breath and epigastric pain, especially when lying down. He has a history of GORD, hypertension and COPD. His vitals are stable. An X-ray is performed. What is the MOST appropriate next step in management?

A. Administer intravenous antibiotics for possible aspiration pneumonia
B. Prescribe a short course of oral corticosteroids for COPD exacerbation
C. Order a barium swallow study to assess esophageal motility
D. Initiate a proton pump inhibitor and schedule an upper endoscopy
E. Perform a diagnostic thoracentesis to rule out pleural effusion
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A 52-year-old woman presents to her general practitioner with fatigue, increased thirst, and frequent urination over the past three months. She has a history of hypertension and hyperlipidemia, for which she takes lisinopril and atorvastatin. Her BMI is 32 kg/m². On examination, her blood pressure is 140/85 mmHg, and her heart rate is 78 bpm. Laboratory tests reveal a fasting plasma glucose of 8.5 mmol/L and an HbA1c of 7.2%. She is diagnosed with type 2 diabetes mellitus. Which of the following is the most appropriate initial management step for this patient according to Australian guidelines?

A. Lifestyle modification including diet and exercise
B. Commencement of insulin therapy
C. Initiation of metformin therapy
D. Referral to an endocrinologist
E. Addition of a sulfonylurea
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A 65-year-old man with a history of hypertension and ischemic heart disease presents to the emergency department with worsening shortness of breath, orthopnea, and peripheral edema. On examination, he has elevated jugular venous pressure, bilateral basal crackles, and pitting edema in the lower limbs. An echocardiogram shows an ejection fraction of 35%. What is the most appropriate initial management step for this patient?

A. Initiate digoxin therapy
B. Perform coronary angiography
C. Start oral beta-blockers
D. Administer intravenous furosemide
E. Prescribe oral ACE inhibitors
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for a routine check-up. He has a history of smoking and hypertension, managed with lisinopril. He denies any abdominal pain, back pain, or lower extremity claudication. Physical exam is unremarkable. A contrast-enhanced CT scan of the abdomen is performed, the axial view is shown. What is the MOST appropriate next step in management?

A. Repeat imaging in 6-12 months
B. Start aspirin for secondary prevention
C. Refer to vascular surgery for elective repair
D. Prescribe a statin for lipid management
E. Initiate beta-blocker therapy
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A 68-year-old man with a history of hypertension, type 2 diabetes, and stable angina is scheduled for elective hernia repair surgery. He is currently on aspirin, metformin, lisinopril, and atorvastatin. His last angina episode was over a year ago, and he has no history of myocardial infarction. What is the most appropriate preoperative management step to minimize his cardiovascular risk during surgery?

A. Discontinue aspirin therapy one week before surgery
B. Increase the dose of atorvastatin
C. Continue aspirin therapy
D. Order a preoperative stress test
E. Start beta-blocker therapy
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A 68-year-old man with a history of hypertension and coronary artery disease presents to the emergency department with worsening shortness of breath and fatigue over the past week. On examination, he has elevated jugular venous pressure, bilateral lung crackles, and peripheral edema. An echocardiogram reveals reduced ejection fraction and dilated ventricles. Which of the following best explains the pathophysiological mechanism leading to his symptoms?

A. Increased peripheral resistance leading to left ventricular hypertrophy
B. Decreased venous return causing systemic hypotension
C. Enhanced myocardial contractility resulting in fluid retention
D. Decreased cardiac output leading to activation of the renin-angiotensin-aldosterone system
E. Increased cardiac output causing pulmonary congestion
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A 62-year-old woman with a 15-year history of type 2 diabetes mellitus presents to her general practitioner with complaints of worsening vision over the past six months. She also reports intermittent tingling and numbness in her feet, which has been progressively worsening. Her diabetes has been poorly controlled, with recent HbA1c levels consistently above 9%. She has a history of hypertension and hyperlipidemia, both of which are managed with medication. On examination, her blood pressure is 140/85 mmHg, and her BMI is 32 kg/m². Fundoscopic examination reveals microaneurysms and cotton wool spots. Urinalysis shows microalbuminuria. Which of the following interventions is most likely to address the underlying pathophysiological mechanism of her visual symptoms?

A. Optimizing glycemic control
B. Prescribing an ACE inhibitor
C. Recommending regular exercise
D. Starting a statin
E. Initiating aspirin therapy
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 72-year-old male presents to the ED with increasing shortness of breath and epigastric pain, especially when lying down. He has a history of GORD, hypertension and COPD. His vitals are stable. An X-ray is performed. What is the MOST likely underlying cause of his presentation?

A. Gastric malignancy
B. Esophageal dysmotility
C. Reduced lower esophageal sphincter tone
D. Aortic aneurysm
E. Pneumonia
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A 62-year-old man with a history of poorly controlled hypertension and type 2 diabetes mellitus presents to his general practitioner for a routine check-up. His current medications include metformin, gliclazide, and amlodipine. His blood pressure today is 160/95 mmHg. His creatinine is 140 umol/L (previously 110 umol/L). His electrolytes are normal. The GP decides to add an ACE inhibitor to his regimen. Which of the following investigations is MOST important to repeat within 1-2 weeks of commencing the ACE inhibitor?

A. Full blood count
B. Fasting blood glucose
C. Serum creatinine and electrolytes
D. Urine albumin creatinine ratio
E. Liver function tests
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

An 80-year-old male with a history of smoking and hypertension presents for investigation of mild, intermittent lower back pain. Physical examination is unremarkable. Vital signs are stable. A CT scan of the abdomen is performed. Based on the provided image and clinical context, what is the most appropriate next step in the management of this patient?

A. Repeat CT scan in 3 months
B. Urgent referral for surgical repair
C. Annual ultrasound surveillance
D. No further follow-up required
E. Initiate antiplatelet therapy and review in 1 year
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A 55-year-old male with a history of hypertension presents for a routine check-up. His blood pressure is consistently measured at 150/95 mmHg despite lifestyle modifications. According to Australian guidelines, what is the most appropriate next step in managing his hypertension?

A. Prescribe a diuretic
B. Increase lifestyle modifications
C. Refer to a cardiologist
D. Start a beta-blocker
E. Initiate an ACE inhibitor
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A 60-year-old woman presents to the emergency department with sudden onset of severe abdominal pain radiating to her back. She has a history of hypertension and hyperlipidemia. On examination, she is hypotensive and tachycardic. Her abdomen is distended and tender, with guarding and rebound tenderness. An abdominal ultrasound reveals a large abdominal aortic aneurysm. What is the most appropriate next step in the management of this patient?

A. Administer intravenous beta-blockers
B. Initiate intravenous antibiotics
C. Immediate surgical repair
D. Perform a CT angiography
E. Start anticoagulation therapy
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension and hyperlipidemia presents to the emergency department with a sudden onset of left-sided hemianopia and mild right-sided weakness. Her symptoms began approximately 4 hours prior to arrival. Initial neurological examination reveals a left homonymous hemianopia, mild right hemiparesis (4/5 strength), and intact sensation. A CT angiogram was performed, and the patient underwent endovascular coiling. The image shows a follow-up angiogram post-procedure. Despite the intervention, the patient's left homonymous hemianopia persists, and her right hemiparesis has not improved. What is the MOST appropriate next step in the management of this patient?

A. Repeat angiography to assess for recanalization or further aneurysm growth
B. Start rehabilitation therapy and monitor for improvement
C. Order an MRI of the brain to evaluate for ischemic changes
D. Prescribe a course of high-dose corticosteroids to reduce peri-aneurysmal edema
E. Initiate dual antiplatelet therapy with aspirin and clopidogrel
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A 35-year-old Aboriginal woman presents for a routine health check. She reports feeling tired lately and sometimes short of breath on exertion. She has a history of type 2 diabetes diagnosed 5 years ago, managed with metformin 500mg twice daily, and untreated hypertension. On examination, her blood pressure is 145/90 mmHg. Urinalysis shows 2+ protein. Blood tests reveal creatinine 180 µmol/L, eGFR 35 mL/min/1.73m², HbA1c 8.5%, potassium 4.2 mmol/L. Given these findings, which of the following is the most appropriate initial management step?

A. Increase the dose of metformin.
B. Prescribe a loop diuretic for fluid overload.
C. Advise dietary protein restriction only.
D. Initiate an ACE inhibitor or ARB and optimise blood pressure control.
E. Refer immediately for renal biopsy.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for a routine check-up. He has a history of smoking and hypertension, well-controlled with medication. He denies any abdominal pain, back pain, or lower extremity claudication. Physical exam is unremarkable. A contrast-enhanced CT scan of the abdomen is performed, the axial view is shown. What is the MOST appropriate next step in management?

A. Referral for immediate surgical repair
B. Repeat imaging in 6-12 months
C. Start aspirin for secondary prevention
D. Initiate beta-blocker therapy
E. Prescribe a statin for lipid management
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A 65-year-old man presents to the emergency department with sudden onset of severe headache, nausea, and vomiting. He has a history of hypertension and is currently on antihypertensive medication. On examination, he is alert but in distress due to the headache. His blood pressure is 180/110 mmHg, heart rate is 90 bpm, and he has no focal neurological deficits. A CT scan of the head shows a subarachnoid hemorrhage. Which of the following is the most appropriate initial management step in this patient?

A. Administer nimodipine to prevent cerebral vasospasm
B. Perform immediate surgical clipping of the aneurysm
C. Administer mannitol to reduce intracranial pressure
D. Start intravenous labetalol to control blood pressure
E. Initiate anticonvulsant therapy to prevent seizures
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A 55-year-old man presents to the emergency department with sudden onset severe abdominal pain radiating to the back. He has a history of hypertension and is a smoker. On examination, he is diaphoretic and in distress, with a blood pressure of 90/60 mmHg and a heart rate of 110 bpm. Abdominal examination reveals a pulsatile mass in the midline. What is the most likely diagnosis?

A. Acute myocardial infarction
B. Acute pancreatitis
C. Perforated peptic ulcer
D. Renal colic
E. Ruptured abdominal aortic aneurysm
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A 45-year-old woman presents to the emergency department with sudden onset of severe headache, described as the worst headache of her life. She also reports nausea and photophobia. Her past medical history is significant for hypertension, which is poorly controlled. On examination, she is alert but in distress, with a blood pressure of 180/110 mmHg, heart rate of 90 bpm, and temperature of 37°C. Neurological examination reveals neck stiffness but no focal neurological deficits. A CT scan of the head is performed and shows no acute intracranial hemorrhage. What is the next best step in management?

A. Lumbar puncture
B. Start intravenous labetalol
C. MRI of the brain
D. Administer sumatriptan
E. Repeat CT scan with contrast
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A 67-year-old man presents to the emergency department with sudden onset of severe chest pain radiating to his back. He describes the pain as tearing in nature. His blood pressure is 180/100 mmHg in the right arm and 160/90 mmHg in the left arm. He has a history of hypertension and is a smoker. An ECG shows no acute ischemic changes. What is the most appropriate next step in the management of this patient?

A. Start intravenous heparin
B. Administer sublingual nitroglycerin
C. Administer aspirin and clopidogrel
D. Order a CT angiography of the chest
E. Perform an urgent coronary angiogram
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old man with a history of hypertension and smoking presents to his GP with mild, intermittent abdominal discomfort. His vital signs are stable, and abdominal examination is soft and non-tender. As part of the workup, a contrast-enhanced CT scan of the abdomen and pelvis is performed. The provided image is an axial view from this study. Based on the clinical context and the findings in the provided image, what is the most appropriate next step in this patient's management?

A. Referral for urgent endovascular repair planning
B. No further action is required at this time
C. Referral to a vascular surgeon for ongoing surveillance
D. Urgent surgical consultation for immediate repair
E. Repeat CT scan in 3 months to assess for growth
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old man presents with concerns about breast enlargement over the past year. He denies pain or tenderness. He takes medication for hypertension. Examination reveals the findings in the image. Which of the following is the MOST appropriate initial investigation?

A. Mammogram and ultrasound
B. Medication review and hormonal blood tests (testosterone, estradiol, LH, FSH)
C. Reassurance and observation
D. Referral to a breast surgeon
E. Fine needle aspiration
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