← Back to Topics

hypothyroidism

Practice targeted AMC-style multiple-choice questions on hypothyroidism.

Related Topics

A 32-year-old woman presents to her GP with a 3-month history of fatigue, weight gain, and feeling cold all the time. She also reports constipation and dry skin. She has no significant past medical history and is not on any medications. On examination, her blood pressure is 120/80 mmHg, heart rate is 60 bpm, and she has a slightly enlarged thyroid gland. Laboratory tests reveal a low free T4 level and an elevated TSH level. Which of the following is the most appropriate initial treatment for this patient?

A. Thyroidectomy
B. Methimazole
C. Propranolol
D. Radioactive iodine therapy
E. Levothyroxine
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 68-year-old woman presents with a 2-week history of progressive weakness in her right arm and leg, associated with a tremor in the right hand. She also reports feeling more tired than usual. Her general practitioner noted an elevated TSH (12 mIU/L, reference range 0.4-4.0 mIU/L) on routine blood tests done a month ago, but free T4 was within the normal range (15 pmol/L, reference range 10-20 pmol/L). On examination, she has mild right-sided hemiparesis (MRC grade 4/5) and a coarse tremor in the right hand, worse with action. Reflexes are brisk on the right. The rest of the neurological exam is unremarkable. She has mild bradycardia (55 bpm) but no other signs of overt hypothyroidism. What is the most appropriate initial investigation?

A. Cerebrospinal fluid analysis
B. Serum anti-thyroid antibodies (e.g., TPO antibodies)
C. CT angiography of the head and neck
D. Repeat thyroid function tests including free T3
E. MRI brain
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 45-year-old woman presents to her general practitioner with a 3-month history of progressive fatigue, weight gain, and cold intolerance. She also reports constipation and dry skin. On examination, her blood pressure is 110/70 mmHg, heart rate is 60 bpm, and she has a delayed relaxation phase of her deep tendon reflexes. Laboratory tests reveal a low free T4 level and an elevated TSH level. Which of the following is the most appropriate initial management?

A. Beta-blockers
B. Levothyroxine
C. Thyroidectomy
D. Methimazole
E. Radioactive iodine therapy
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 60-year-old woman presents to her GP with a 3-month history of fatigue, weight gain, and feeling cold all the time. She also reports constipation and dry skin. On examination, she has a slow heart rate and her skin appears dry and coarse. What is the most appropriate initial investigation?

A. Serum TSH level
B. Complete blood count
C. Serum cortisol level
D. Liver function tests
E. Serum calcium level
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 45-year-old woman presents to the clinic with a 6-month history of fatigue, weight gain, and feeling cold all the time. She also reports hair loss and constipation. On examination, her skin is dry, and her reflexes are delayed. Her blood pressure is 110/70 mmHg, and her heart rate is 60 bpm. Laboratory tests reveal a low free T4 and elevated TSH. What is the most likely diagnosis?

A. Hyperthyroidism
B. Primary hypothyroidism
C. Cushing's syndrome
D. Iron deficiency anemia
E. Subclinical hypothyroidism
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 45-year-old woman presents with fatigue, weight gain, and cold intolerance. On examination, she has dry skin and a delayed relaxation phase of deep tendon reflexes. Her TSH level is elevated, and free T4 is low. What is the most appropriate treatment for her condition?

A. Radioactive iodine therapy
B. Methimazole
C. Beta-blockers
D. Levothyroxine
E. Surgical thyroidectomy
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 45-year-old woman presents to her general practitioner with a 3-month history of fatigue, weight gain, and feeling cold all the time. She also reports constipation and dry skin. On examination, her heart rate is 55 bpm, and she has a delayed relaxation phase of her deep tendon reflexes. What is the most likely diagnosis?

A. Chronic fatigue syndrome
B. Iron deficiency anemia
C. Hypothyroidism
D. Cushing's syndrome
E. Depression
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 30-year-old woman presents to her GP with fatigue, weight gain, and cold intolerance over the past 6 months. She also reports constipation and dry skin. On examination, she has a slightly enlarged, non-tender thyroid gland. Her TSH level is elevated, and free T4 is low. What is the most appropriate treatment for this condition?

A. Radioactive iodine therapy
B. Levothyroxine
C. Methimazole
D. Beta-blockers
E. Thyroidectomy
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 50-year-old woman presents to her GP with a 3-month history of fatigue, weight gain, and feeling cold all the time. She also reports constipation and dry skin. On examination, she has a slow heart rate and delayed relaxation of deep tendon reflexes. Her thyroid function tests show elevated TSH and low free T4 levels. What is the most appropriate treatment for her condition?

A. Radioactive iodine therapy
B. Methimazole
C. Beta-blockers
D. Surgical thyroidectomy
E. Levothyroxine
Mark this as a high-quality question
Mark this as a poor-quality or problematic question

A 32-year-old woman presents to her general practitioner with a 2-month history of fatigue, weight gain, and feeling cold all the time. She also reports hair loss and constipation. On examination, her heart rate is 58 bpm, and she has dry skin and a delayed relaxation phase of the deep tendon reflexes. Her thyroid function tests reveal a high TSH level and low free T4. She has no significant past medical history and is not on any medications. Which of the following is the most appropriate initial management for her condition?

A. Propranolol
B. Radioactive iodine therapy
C. Methimazole
D. Thyroidectomy
E. Levothyroxine
Mark this as a high-quality question
Mark this as a poor-quality or problematic question