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itchy

Practice targeted AMC-style multiple-choice questions on itchy.

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A 32-year-old male presents to his GP complaining of a new, intensely itchy rash on his wrists and ankles. On examination, there are multiple small, flat-topped, polygonal, violaceous papules. Some of the papules have fine white lines on their surface. What is the most likely diagnosis?

A. Lichen planus
B. Psoriasis
C. Tinea corporis
D. Contact dermatitis
E. Atopic dermatitis
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A 10-year-old boy presents to his GP with a chronic, intensely itchy rash affecting the flexural areas of his elbows and knees, as well as his neck. His parents report that he has had this condition on and off since infancy, with periods of remission and exacerbation. He also has a history of allergic rhinitis and asthma. On examination, the skin in the affected areas is dry, lichenified, and excoriated. There are also scattered papules and plaques. The patient reports significant sleep disturbance due to the itch. Topical corticosteroids have provided temporary relief in the past, but the rash flares up again soon after stopping treatment. Which of the following is the MOST appropriate next step in managing this patient's atopic dermatitis?

A. Refer the patient to a dermatologist for systemic immunosuppressant therapy without attempting further topical treatments.
B. Initiate treatment with a topical calcineurin inhibitor such as tacrolimus or pimecrolimus.
C. Recommend oral antihistamines as the sole treatment for the itch.
D. Advise strict avoidance of all potential allergens based on unproven allergy testing.
E. Prescribe a potent topical corticosteroid for long-term daily use.
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A 45-year-old woman presents with a 3-month history of an intensely itchy rash on her wrists and ankles. On examination, you note violaceous, flat-topped papules. What is the most likely diagnosis?

A. Tinea corporis
B. Contact dermatitis
C. Psoriasis
D. Lichen planus
E. Atopic dermatitis
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A 32-year-old woman presents to her GP complaining of a new, intensely itchy rash on her elbows, knees, and scalp. On examination, the GP notes symmetrical, erythematous papules and plaques with overlying silvery scales. The patient reports a family history of similar skin conditions. What is the most likely diagnosis?

A. Contact Dermatitis
B. Tinea Corporis
C. Pityriasis Rosea
D. Eczema (Atopic Dermatitis)
E. Psoriasis
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A 6-year-old child presents with intensely itchy, small, fluid-filled blisters on their hands and feet. The blisters are most prominent on the palms and soles. The child has a history of atopic dermatitis. What is the most likely diagnosis?

A. Pompholyx eczema
B. Contact dermatitis
C. Scabies
D. Bullous impetigo
E. Hand, foot, and mouth disease
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 65-year-old woman presents with a chronic, non-healing lesion at the site of her mastectomy scar, performed 7 years ago. She denies pain but reports occasional itching. What is the MOST appropriate next investigation?

A. Mammogram of the contralateral breast
B. Fungal culture
C. Topical corticosteroid application
D. Excisional biopsy with wide margins
E. Skin biopsy
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A 6-month-old infant is brought to the general practitioner by his parents, who are concerned about a persistent, itchy rash. The rash initially appeared on his cheeks and scalp a few weeks ago and has now spread to his trunk and extensor surfaces of his arms and legs. The parents report that the infant is constantly scratching, which disrupts his sleep. He has no known allergies, and there is no family history of asthma or allergic rhinitis. On examination, the infant is alert and active. There are erythematous, papular lesions with areas of weeping and crusting on his cheeks, scalp, trunk, and extensor surfaces. The skin is dry and flaky in other areas. Which of the following is the MOST appropriate initial management strategy for this infant's condition?

A. Systemic corticosteroids
B. Referral to a dermatologist for allergy testing
C. Oral antihistamines and topical antibiotics
D. Emollients and topical corticosteroids
E. Elimination diet for the mother (if breastfeeding)
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash that started a few weeks ago. She reports that it began on her wrists and ankles and has now spread to her elbows and knees. She denies any new medications, travel, or changes in personal care products. On examination, you observe symmetrical, excoriated papules and plaques on her wrists, elbows, knees, and upper back. Some of the papules have small blisters. Which of the following is the most appropriate initial investigation?

A. Patch testing with a standard allergen series
B. Potassium hydroxide (KOH) examination of skin scraping
C. Serum IgE level
D. Skin biopsy for direct immunofluorescence
E. Viral culture of blister fluid
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A 32-year-old woman, G1P1, presents to her general practitioner at 34 weeks gestation complaining of a new, intensely itchy rash. The rash started on her abdomen around the umbilicus and has now spread to her thighs and buttocks. On examination, there are erythematous papules and plaques, some with vesicles, located within the striae distensae of her abdomen. She denies any personal or family history of eczema or other skin conditions. She is otherwise well, with normal blood pressure and no proteinuria. Fetal movements are normal. Which of the following is the most appropriate initial management?

A. Oral corticosteroids
B. Topical corticosteroids and emollients
C. Referral to a dermatologist for biopsy
D. Induction of labour
E. Oral antihistamines alone
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A 4-year-old boy is brought to the clinic by his parents due to a persistent itchy rash on his arms and legs. The rash has been present for several weeks and seems to worsen at night. The child has a history of asthma and allergic rhinitis. On examination, there are erythematous, scaly patches with excoriations on the flexural surfaces of his arms and legs. What is the most likely diagnosis?

A. Scabies
B. Psoriasis
C. Contact dermatitis
D. Atopic dermatitis
E. Tinea corporis
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 55-year-old man presents to his GP with a persistent lesion on his nose that has been present for several months and has not changed significantly in size or appearance. He reports it is occasionally itchy but otherwise asymptomatic. His medical history is unremarkable, and vital signs are within normal limits. On examination, you observe the lesion shown in the image. Considering the appearance of this lesion, what is the most appropriate initial step in the management of this patient?

A. Perform a punch or shave biopsy of the lesion.
B. Advise watchful waiting and review in 6 months if it changes.
C. Prescribe a 7-day course of oral flucloxacillin.
D. Initiate treatment with topical hydrocortisone 1%.
E. Refer for Mohs micrographic surgery.
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash on her elbows, knees, and scalp for the past 6 months. She reports that the itching is worse at night and after hot showers. She has tried over-the-counter hydrocortisone cream without relief. On examination, the GP notes symmetrical, excoriated papules and plaques on the extensor surfaces of her elbows and knees, as well as some scaling on her scalp. The patient also mentions a history of recurrent mouth ulcers. Which of the following is the MOST appropriate initial investigation to confirm the suspected diagnosis?

A. Skin biopsy for histopathology and direct immunofluorescence
B. Allergy testing (skin prick or RAST) for common environmental allergens
C. Full blood count (FBC) and liver function tests (LFTs)
D. Potassium hydroxide (KOH) examination of skin scrapings
E. IgA anti-endomysial antibody (EMA) and IgA tissue transglutaminase (tTG) antibody testing
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 65-year-old woman presents with a several-month history of a slowly enlarging, mildly pruritic skin lesion on her left chest wall. She underwent a simple mastectomy on the left side for invasive ductal carcinoma 8 years ago. She denies systemic symptoms. Physical examination reveals the appearance shown. What is the most appropriate next step in management?

A. Punch biopsy of the lesion
B. Arrange a CT scan of the chest, abdomen, and pelvis
C. Order a mammogram of the right breast
D. Reassure the patient and review in 6 months
E. Prescribe a high-potency topical steroid cream
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 62-year-old woman presents for a routine follow-up appointment several years after undergoing a simple mastectomy for pT1N0M0 invasive ductal carcinoma of the left breast. She completed adjuvant endocrine therapy and has been well since. During the consultation, she mentions that she has noticed a persistent area of skin change on her left chest wall, near the mastectomy scar, over the past few months. She describes it as occasionally itchy and slightly raised, but denies pain, discharge, or systemic symptoms such as weight loss or fever. Her vital signs are stable, and physical examination reveals no palpable axillary or supraclavicular lymphadenopathy. The appearance of the affected area is shown in the image. Considering the patient's history and the clinical presentation, what is the most appropriate initial diagnostic step?

A. Arrange for a PET-CT scan to assess for metastatic disease
B. Perform fine needle aspiration cytology of the lesion
C. Prescribe a course of topical antifungal cream and review in two weeks
D. Excisional or incisional biopsy of the lesion
E. Reassure the patient that this is likely post-surgical scarring and review in six months
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A 6-year-old child presents with intensely itchy, small, fluid-filled blisters on their hands and feet, especially between the fingers and toes. The lesions are linear and excoriated. Multiple family members have similar symptoms. What is the most likely diagnosis?

A. Scabies
B. Chickenpox
C. Hand, foot, and mouth disease
D. Atopic dermatitis
E. Contact dermatitis
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 68-year-old woman presents with a persistent, pruritic rash on her chest wall at the site of a previous mastectomy performed 8 years ago for invasive ductal carcinoma. She completed adjuvant chemotherapy and radiation at that time. Examination reveals the area shown. What is the MOST appropriate next step in management?

A. Topical corticosteroid application
B. Referral for excisional re-resection
C. Mammogram of the contralateral breast
D. Empiric antifungal treatment
E. Skin biopsy of the affected area
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A 5-year-old girl presents with an itchy bottom at night, worse at night, suggestive of threadworm infection. What is the best treatment for her infection in the Australian context?

A. Advise dietary changes, such as reducing sugar intake, as the primary treatment.
B. Recommend applying a topical anti-itch cream to the perianal area.
C. Treat only the affected child with a single dose of pyrantel.
D. Reassure the parents that this is common and has low morbidity, requiring no treatment.
E. Treat the whole family with pyrantel or mebendazole, and repeat in 2 weeks.
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash that started a few weeks ago. She reports that it began on her wrists and ankles and has now spread to her elbows and knees. She denies any new medications, travel, or changes in personal care products. On examination, you observe symmetrical, intensely pruritic, violaceous, flat-topped papules and plaques on her wrists, ankles, and shins. Some of the lesions show fine, white lines on the surface. There are also a few small, similar lesions on her buccal mucosa. Which of the following is the most appropriate initial management?

A. Systemic corticosteroids and antifungal cream
B. Topical corticosteroids and antihistamines
C. Oral antibiotics and topical emollients
D. Referral to a rheumatologist for autoimmune workup
E. Cryotherapy to the affected areas
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