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computed tomography (CT)

Practice targeted AMC-style multiple-choice questions on computed tomography (CT).

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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department complaining of abdominal pain, distension, and obstipation for the past 3 days. He reports a history of multiple abdominal surgeries for adhesions. His vital signs are: HR 110 bpm, BP 110/70 mmHg, RR 22 breaths/min, SpO2 97% on room air, and temperature 37.8°C. Physical examination reveals a distended abdomen with high-pitched bowel sounds. An upright abdominal X-ray is performed, as shown. Given the clinical context and the findings on the imaging, what is the MOST appropriate next imaging investigation to guide management?

A. CT abdomen and pelvis with intravenous contrast
B. Repeat plain abdominal X-ray in 6 hours
C. MRI abdomen
D. Barium enema
E. Upper GI series with small bowel follow-through
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old man with a history of smoking, hypertension, and dyslipidaemia presents for investigation of intermittent flank pain. Physical examination is unremarkable. Routine blood tests are normal. A CT scan of the abdomen is performed. Considering the findings demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. Surveillance with abdominal ultrasound in 12 months
B. Urgent referral for surgical assessment and repair planning
C. Referral for immediate endovascular aneurysm repair
D. No specific follow-up imaging required, focus on risk factor modification
E. Repeat CT scan of the abdomen in 3 months
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 35-year-old presents with colicky abdominal pain and vomiting. An X-ray is performed. What is the MOST likely finding on subsequent CT imaging?

A. Splenic infarct
B. Pneumatosis intestinalis
C. Free intraperitoneal air
D. Mesenteric stranding
E. Transition point with proximal bowel dilatation
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male with a history of hypertension and smoking undergoes a CT scan for investigation of chronic back pain. He denies any abdominal pain, pulsatile mass, or leg ischaemia. His blood pressure is 130/80 mmHg, pulse 72 bpm. The image provided is an axial view from this scan. Based on this finding, what is the most appropriate next step in his management?

A. Arrange for urgent surgical consultation.
B. No further follow-up is required.
C. Arrange for surveillance ultrasound in 12 months.
D. Schedule elective endovascular aneurysm repair (EVAR).
E. Repeat CT angiography in 6 months.
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old man presents to the emergency department with a 2-day history of worsening left lower quadrant abdominal pain, associated with subjective fever, chills, and nausea. He reports some recent constipation. On examination, his temperature is 38.5°C, pulse 95 bpm, BP 130/80 mmHg. Abdominal examination reveals tenderness and guarding in the left iliac fossa. Bowel sounds are reduced. Blood tests show a white cell count of 15 x 10^9/L (neutrophils 85%) and C-reactive protein of 120 mg/L. Urea, electrolytes, and creatinine are within normal limits. A CT scan of the abdomen and pelvis is performed (image provided). Considering the clinical presentation and the findings demonstrated in the provided image, which of the following represents the most appropriate initial management strategy?

A. Conservative management with analgesia and observation.
B. Oral antibiotics and outpatient management.
C. Urgent surgical resection of the affected segment.
D. Colonoscopy to assess the severity of diverticular disease.
E. Intravenous antibiotics and consider percutaneous drainage.
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Neuroblastoma, CT of the abdomen
Image by RadsWiki CC BY-SA 3.0 · Source

A 4-year-old boy presents with left flank pain and a palpable abdominal mass. His mother reports decreased appetite and recent weight loss. A CT scan of the abdomen is performed (image attached). What is the MOST likely diagnosis?

A. Lymphoma
B. Hepatoblastoma
C. Wilms tumor
D. Renal cell carcinoma
E. Neuroblastoma
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents to the emergency department complaining of left lower quadrant abdominal pain for the past three days. He describes the pain as constant and sharp, rating it an 8 out of 10. He also reports nausea, decreased appetite, and subjective fevers. His past medical history is significant for hypertension and hyperlipidemia, both well-controlled with medications. He denies any recent travel or sick contacts. On physical examination, his abdomen is tender to palpation in the left lower quadrant with guarding. Bowel sounds are present but diminished. The remainder of his examination is unremarkable. His vital signs are: Temperature 38.2°C, Heart Rate 98 bpm, Blood Pressure 140/90 mmHg, Respiratory Rate 18 breaths per minute, and Oxygen Saturation 98% on room air. Laboratory results show a white blood cell count of 14,000/µL with a neutrophilic predominance. A CT scan of the abdomen and pelvis with intravenous contrast is performed, and a representative image is shown. Assuming the patient has no allergies, what is the MOST appropriate initial management strategy?

A. Perform a colonoscopy to evaluate for inflammatory bowel disease.
B. Administer intravenous antibiotics covering gram-negative and anaerobic organisms, and admit the patient for observation and further management.
C. Schedule an elective laparoscopic sigmoid colectomy.
D. Prescribe oral antibiotics and instruct the patient to follow up with their primary care physician in one week.
E. Order a barium enema to assess for colonic strictures or masses.
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents with increasing shortness of breath and epigastric discomfort, particularly after meals. He has a history of GERD. Physical examination reveals decreased breath sounds at the left lung base. An axial CT image is shown. Considering the clinical presentation and imaging findings, what is the MOST appropriate next step in management?

A. Arrange urgent upper gastrointestinal endoscopy
B. Request a barium swallow study
C. Referral for surgical repair
D. Discharge with advice on lifestyle modification and follow-up
E. Initiate high-dose proton pump inhibitor therapy
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 58-year-old woman with poorly controlled diabetes presents with severe RUQ pain, fever, and vomiting for 3 days. The provided CT was performed. What is the MOST appropriate initial management strategy?

A. Urgent cholecystectomy
B. Oral ursodeoxycholic acid
C. IV antibiotics and bowel rest
D. Percutaneous cholecystostomy tube placement
E. ERCP with stone extraction
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 78-year-old male presents to the emergency department with a 6-hour history of sudden onset, severe pain and swelling in his right groin. He reports nausea but no vomiting. On examination, there is a tender, firm, non-reducible lump in the right inguinal region. Bowel sounds are present. Vitals are stable: BP 130/80, HR 75, Temp 36.8°C. A CT scan of the pelvis is performed, shown in the image. Based on the clinical presentation and the findings demonstrated in the image, what is the most appropriate immediate next step in the management of this patient?

A. Order a follow-up ultrasound in 24 hours
B. Urgent surgical exploration and repair
C. Attempt manual reduction under sedation
D. Administer intravenous antibiotics and observe
E. Discharge home with analgesia and advice to return if symptoms worsen
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Neuroblastoma, CT of the abdomen
Image by RadsWiki CC BY-SA 3.0 · Source

A 2-year-old with a palpable abdominal mass and periorbital ecchymoses has the shown CT. What is the MOST likely diagnosis?

A. Hepatoblastoma
B. Neuroblastoma
C. Rhabdomyosarcoma
D. Lymphoma
E. Wilms tumor
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension and hyperlipidemia presents to the emergency department with a sudden onset of left-sided hemianopia and mild right-sided weakness. Her symptoms began approximately 4 hours prior to arrival. Initial neurological examination reveals intact language function and no cognitive deficits. A CT angiogram was performed, followed by endovascular coiling. The provided image shows a post-operative angiogram. Despite the intervention, the patient's hemianopia persists, and her weakness has slightly worsened. What is the MOST appropriate next step in the management of this patient?

A. Administer intravenous thrombolysis with alteplase
B. Prescribe a course of high-dose corticosteroids to reduce cerebral edema
C. Repeat angiography to assess for recanalization or further aneurysm growth
D. Start the patient on nimodipine to prevent vasospasm
E. Initiate dual antiplatelet therapy with aspirin and clopidogrel
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 72-year-old male with a history of hypertension presents with a sudden onset of right-sided weakness and expressive aphasia. He underwent endovascular coiling for a PCA aneurysm 1 year ago. The attached image was obtained. What is the MOST likely cause of his current presentation?

A. Seizure activity causing postictal paralysis
B. Thromboembolic event related to aneurysm recurrence
C. Vasospasm of the posterior cerebral artery
D. New aneurysm formation in the anterior circulation
E. Hemorrhagic conversion of a previous infarct
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old woman presents with 24 hours of severe right upper quadrant pain, fever, and nausea. Examination reveals RUQ tenderness and a positive Murphy's sign. Vitals: T 38.5°C, HR 105, BP 130/80, RR 18, SpO2 98% RA. Labs: WCC 16, CRP 120, LFTs normal. An urgent abdominal CT is performed. Considering the clinical presentation and the findings on the provided imaging, what is the most appropriate definitive management strategy for this patient?

A. Percutaneous cholecystostomy tube placement.
B. Urgent endoscopic retrograde cholangiopancreatography (ERCP).
C. Intravenous antibiotics and delayed laparoscopic cholecystectomy in 6-8 weeks.
D. Laparoscopic cholecystectomy within 72 hours.
E. Oral antibiotics and analgesia with outpatient surgical referral.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old man presents with 2 days of left lower quadrant abdominal pain, fever, and nausea. On examination, he is afebrile, haemodynamically stable, with localised tenderness in the LLQ. Blood tests show a WCC of 14.5. A CT scan of the abdomen and pelvis is performed. Considering the clinical presentation and the findings demonstrated in the image, what is the most appropriate initial management plan?

A. Admission for IV antibiotics and observation
B. Colonoscopy within 24 hours
C. Urgent surgical consultation for laparotomy
D. Outpatient oral antibiotics and analgesia
E. Discharge with advice to return if symptoms worsen
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 58-year-old male with cirrhosis presents for routine surveillance. His AFP is elevated. A CT scan with contrast is performed (image attached). What is the MOST appropriate next step to determine definitive management?

A. Percutaneous ethanol injection
B. Repeat CT scan in 3 months
C. Initiate sorafenib therapy
D. Systemic chemotherapy
E. Referral to hepatology for consideration of liver transplant
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 28-year-old male presents with a persistent cough and fatigue. A PET-CT scan was performed. What is the MOST likely diagnosis?

A. Lung abscess
B. Pneumocystis pneumonia
C. Aspergilloma
D. Bronchogenic carcinoma
E. Tuberculoma
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Ovarian Cyst
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 28-year-old female presents to the ED with acute onset right lower quadrant pain. She reports nausea and vomiting. Her last menstrual period was 6 weeks ago, and she denies any vaginal bleeding. She is hemodynamically stable. A CT scan of the abdomen and pelvis is performed, with a relevant image shown. Considering the clinical presentation and the imaging findings, what is the MOST appropriate next step in the management of this patient?

A. Order a pelvic ultrasound
B. Administer intravenous fluids and observe for symptom resolution
C. Outpatient follow-up with repeat imaging in 6 weeks
D. Laparoscopic surgical exploration
E. Initiate broad-spectrum antibiotics
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old male presents with postprandial vomiting and persistent retrosternal discomfort. He reports feeling full quickly after eating only small amounts. An abdominal CT scan is performed, the axial view is shown. What is the MOST likely underlying mechanism contributing to this patient's symptoms?

A. Gastric malignancy
B. Pyloric stenosis
C. Esophageal dysmotility
D. Mechanical obstruction of the gastric outflow
E. Increased gastric acid production
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old man presents with sudden onset of severe right groin pain and a firm, non-reducible bulge. He reports mild nausea but denies vomiting or change in bowel habit. Vital signs are stable. A CT scan of the pelvis is performed, as shown. Considering the clinical context and the imaging findings, what is the most appropriate immediate management?

A. Obtain a groin ultrasound for further assessment
B. Attempt manual reduction under sedation
C. Arrange for elective surgical consultation
D. Administer analgesia and observe closely
E. Emergency surgical exploration and repair
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Ovarian Cyst
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 28-year-old female presents to the ED with acute onset right lower quadrant pain. She reports nausea and vomiting. Her last menstrual period was 6 weeks ago, and she denies any vaginal bleeding. She is hemodynamically stable. A CT scan of the abdomen and pelvis is performed, with a relevant image shown. What is the MOST appropriate next step in the management of this patient?

A. Emergency hysterectomy
B. Laparoscopic cystectomy
C. Administration of broad-spectrum antibiotics
D. Initiate anticoagulation therapy
E. Expectant management with analgesia
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Neuroblastoma, CT of the abdomen
Image by RadsWiki CC BY-SA 3.0 · Source

A 4-year-old presents with abdominal distension and back pain for 2 months. Exam reveals a firm, fixed abdominal mass. Vitals are normal. An abdominal CT is performed (axial view shown). Which lab finding would MOST strongly support the suspected diagnosis?

A. Elevated urine vanillylmandelic acid (VMA)
B. Elevated serum lactate dehydrogenase (LDH)
C. Elevated alpha-fetoprotein (AFP)
D. Elevated urine urobilinogen
E. Elevated serum amylase
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 32-year-old male with a history of Crohn's disease presents with worsening abdominal pain, diarrhea, and a low-grade fever. He reports that his symptoms have been progressively worsening over the past few weeks despite being compliant with his prescribed mesalamine. A CT scan of the abdomen and pelvis is performed, as shown. What is the MOST appropriate next step in management?

A. Schedule a colonoscopy with biopsy
B. Start a course of oral prednisone
C. Initiate infliximab therapy
D. Increase the dose of mesalamine
E. Prescribe a course of oral ciprofloxacin and metronidazole
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 58-year-old male presents with left lower quadrant abdominal pain and a low-grade fever. The provided image was obtained. What is the most likely diagnosis?

A. Ovarian cyst
B. Sigmoid volvulus
C. Diverticulitis
D. Appendicitis
E. Ulcerative colitis
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 62-year-old male presents with a 3-month history of worsening upper abdominal pain, significant fatigue, and a 10 kg unintentional weight loss. His medical history includes long-standing peptic ulcer disease managed with proton pump inhibitors. On examination, he has mild hepatomegaly and trace ascites. Initial blood tests show elevated alkaline phosphatase and gamma-glutamyl transferase, with normal serum bilirubin and transaminases. A contrast-enhanced CT scan of the abdomen and pelvis is performed, and representative images are provided. Considering the clinical presentation and the findings demonstrated on the imaging, which of the following represents the MOST appropriate immediate next step in the management of this patient?

A. Commencement of empirical systemic chemotherapy
B. Urgent upper endoscopy with gastric biopsies
C. Immediate referral to palliative care services
D. Image-guided biopsy of a liver lesion
E. Referral for surgical assessment for liver metastasectomy
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents to the ED with increasing shortness of breath and epigastric discomfort, particularly after meals. He has a history of well-controlled hypertension and takes no regular medications. Physical examination reveals decreased breath sounds at the left lung base. An abdominal CT scan is performed, the axial view is shown. What is the MOST appropriate next step in management?

A. Discharge with reassurance and follow-up with a gastroenterologist in 6 months
B. Barium swallow study to further evaluate the anatomy
C. Surgical consultation for elective repair
D. Initiate a trial of proton pump inhibitors and lifestyle modifications
E. Esophageal manometry to assess esophageal motility
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Neuroblastoma, CT of the abdomen
Image by RadsWiki CC BY-SA 3.0 · Source

A 3-year-old presents with abdominal distension and vague pain. Vitals are stable. An abdominal CT is performed (image attached). Elevated levels of HVA and VMA are noted in the urine. What is the MOST likely origin of the primary lesion?

A. Spleen
B. Pancreas
C. Liver
D. Adrenal gland
E. Kidney
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 68-year-old male presents with fatigue, weight loss, and vague abdominal discomfort. His past medical history includes a recent diagnosis of gastric mixed adenoneuroendocrine carcinoma (MANEC). A CT scan of the abdomen is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. Surgical resection of the affected liver segments
B. Initiation of palliative care and symptom management
C. Percutaneous radiofrequency ablation of liver lesions
D. Observation with serial imaging in three months
E. Referral to medical oncology for systemic chemotherapy
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents with left lower quadrant pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed (image attached). Assuming the diagnosis, which of the following is the MOST appropriate initial management?

A. Colonoscopy to rule out malignancy
B. Oral antibiotics and outpatient follow-up
C. IV antibiotics, bowel rest, and surgical consultation
D. Stool culture and empiric antibiotics
E. High-fiber diet and increased fluid intake
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old patient with a known history of multiple cutaneous vascular lesions presents to the emergency department with a 2-day history of intermittent, colicky abdominal pain and nausea. They report chronic fatigue and have a history of iron deficiency anaemia requiring occasional transfusions. On physical examination, vital signs are stable (BP 120/80, HR 75, RR 16, Temp 36.8°C). There is mild diffuse abdominal tenderness without guarding or rebound. Cutaneous examination reveals multiple blue-purple papules and nodules scattered over the trunk and limbs. An abdominal CT scan is performed. Considering the patient's clinical presentation, known history, and the findings demonstrated in the provided image, what is the most appropriate initial management strategy?

A. Discharge home with oral analgesia and urgent outpatient gastroenterology follow-up.
B. Inpatient medical management with pain control, intravenous fluids, and close observation for signs of obstruction or bleeding.
C. Immediate referral for small bowel capsule endoscopy to identify bleeding sources.
D. Initiate empirical treatment with intravenous antibiotics for suspected enteritis.
E. Urgent surgical exploration for reduction of the identified findings.
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 28-year-old female presents to her general practitioner with a 6-month history of intermittent abdominal pain, predominantly in the right lower quadrant. She describes the pain as cramping and associated with occasional episodes of non-bloody diarrhea. She denies fever, weight loss, or recent travel. Her past medical history is significant for well-controlled asthma, for which she uses an inhaled corticosteroid as needed. Physical examination reveals mild tenderness to palpation in the right lower quadrant, but is otherwise unremarkable. Bowel sounds are normal. Initial laboratory investigations, including a complete blood count and comprehensive metabolic panel, are within normal limits. Stool studies for ova and parasites, bacterial culture, and Clostridium difficile toxin are negative. Given her persistent symptoms, the GP refers her for further evaluation. A CT enterography is performed, and relevant images are shown. Based on the clinical presentation and imaging findings, which of the following is the MOST likely long-term complication this patient is at increased risk of developing?

A. Toxic megacolon
B. Fulminant colitis
C. Small bowel obstruction
D. Erosive esophagitis
E. Primary sclerosing cholangitis
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male undergoes a CT scan for investigation of chronic back pain. He has no history of abdominal pain or pulsatile mass. His blood pressure is 130/80 mmHg. The image provided is an axial view from this scan. Based on this finding and the patient's clinical status, what is the most appropriate next step in management according to current guidelines?

A. Schedule elective endovascular aneurysm repair (EVAR).
B. Arrange for surveillance ultrasound in 12 months.
C. Arrange for urgent surgical consultation.
D. Repeat CT angiography in 6 months.
E. No further follow-up is required.
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 48-year-old man with multiple cutaneous hemangiomas presents with crampy abdominal pain and guaiac-positive stools. The provided image was obtained. What is the MOST appropriate initial diagnostic test to identify the source of bleeding?

A. Tagged red blood cell scan
B. Upper endoscopy
C. Barium swallow
D. Colonoscopy
E. Capsule endoscopy
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 58-year-old male with a 15-year history of chronic hepatitis B infection and established cirrhosis presents for a routine surveillance appointment. He reports feeling generally well, with no significant weight loss, abdominal pain, or jaundice. He denies alcohol use. On examination, his vital signs are stable. He has mild palmar erythema but no ascites or peripheral oedema. Liver span is normal. Recent blood tests show platelet count 120 x 10^9/L, albumin 35 g/L, INR 1.2, total bilirubin 20 µmol/L, ALT 40 U/L, AST 55 U/L, creatinine 80 µmol/L. Alpha-fetoprotein (AFP) has risen from 50 µg/L six months ago to 450 µg/L today. A triphasic CT scan of the abdomen was performed as part of the surveillance protocol, axial views of which are provided. Considering the patient's clinical history, laboratory trends, and the findings demonstrated on the provided imaging, which of the following represents the MOST appropriate immediate next step in the management of this patient?

A. Proceed directly to percutaneous biopsy of the lesion for histological confirmation.
B. Referral to a multidisciplinary liver tumour board for discussion regarding potential treatment options including liver transplantation.
C. Schedule a follow-up CT scan in three months to assess for interval change.
D. Perform an upper endoscopy to screen for oesophageal varices.
E. Initiate systemic chemotherapy with sorafenib.
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 78-year-old male on warfarin for atrial fibrillation presents to the emergency department with sudden onset of severe dyspnoea and right-sided pleuritic chest pain. He denies trauma. On examination, he is tachypnoeic, oxygen saturation is 92% on room air. Blood pressure 110/70 mmHg, heart rate 95 bpm. Chest examination reveals decreased breath sounds on the right. A CT scan of the chest is performed. Considering the patient's clinical presentation, medical history, and the findings demonstrated in the provided image, which of the following represents the most appropriate immediate management strategy?

A. Arrange for urgent bronchoscopy to investigate airway obstruction.
B. Increase warfarin dose and monitor INR.
C. Observe closely in the emergency department with serial chest X-rays.
D. Administer broad-spectrum antibiotics and arrange for thoracentesis.
E. Administer Vitamin K and Prothrombinex (PCC) and arrange for chest tube insertion.
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Ovarian Cyst
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 35-year-old female presents with chronic pelvic pain. The provided CT was performed. What is the MOST appropriate initial management?

A. Laparoscopic cystectomy
B. CA-125 level
C. Trial of oral contraceptives
D. Observation with repeat imaging in 6 weeks
E. Immediate laparotomy
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old male presents with LLQ pain, fever, and increased WBC. A CT scan is performed. He is hemodynamically stable. Based on the image, which of the following is the MOST appropriate initial management strategy?

A. Surgical resection of the affected bowel segment
B. IV antibiotics and bowel rest
C. Flexible sigmoidoscopy to assess the extent of inflammation
D. Percutaneous drainage of any abscesses
E. Oral antibiotics and outpatient follow-up
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old man presents to his GP with a 2-day history of constant, dull aching pain in the left lower quadrant of his abdomen. He reports mild nausea but no vomiting. His bowel movements have been normal. He denies fever or chills. His past medical history includes well-controlled hypertension. On examination, he is afebrile (37.2°C), blood pressure is 135/85 mmHg, heart rate 72 bpm, respiratory rate 16 bpm. Abdominal examination reveals mild tenderness on deep palpation in the left iliac fossa, without guarding or rebound tenderness. Bowel sounds are normal. Digital rectal examination is unremarkable. Laboratory investigations show a white cell count of 10.5 x 10^9/L (normal range 4-11) and a C-reactive protein of 25 mg/L (normal <5). A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's clinical presentation and the findings demonstrated in the provided image, which of the following represents the most appropriate initial management strategy?

A. Initiate a course of oral antibiotics and provide analgesia for outpatient management.
B. Admit the patient for intravenous antibiotics and close observation.
C. Arrange for urgent surgical consultation for potential intervention.
D. Schedule a colonoscopy within the next 48 hours to assess the colonic mucosa.
E. Discharge the patient with only simple analgesia and advice on a low-fibre diet.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old man presents for a routine check-up. He reports occasional mild, non-radiating abdominal discomfort over the past few months, which he attributes to indigestion. He has a history of well-controlled hypertension and hyperlipidaemia, and quit smoking 10 years ago. Physical examination is unremarkable, with no palpable abdominal masses. Routine blood tests are within normal limits. An abdominal CT scan is performed to investigate the abdominal discomfort. Considering the findings demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. Initiate a trial of proton pump inhibitors for presumed dyspepsia.
B. Arrange immediate CT angiography to plan for endovascular repair.
C. Schedule a surveillance ultrasound in 6-12 months.
D. Reassure the patient that the findings are benign and require no follow-up.
E. Refer urgently for vascular surgical assessment.
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 62-year-old male presents to the emergency department complaining of worsening abdominal pain, fatigue, and a 10kg unintentional weight loss over the past 3 months. He reports a history of peptic ulcer disease treated with long-term proton pump inhibitors. Physical examination reveals mild hepatomegaly and trace ascites. Initial laboratory investigations show elevated alkaline phosphatase and gamma-glutamyl transferase (GGT), with normal bilirubin and transaminases. A CT scan of the abdomen and pelvis with contrast is performed, and relevant images are shown. Given the clinical presentation and the findings on the imaging, which of the following is the MOST appropriate next step in management?

A. Initiation of ursodeoxycholic acid for presumed primary biliary cholangitis
B. Observation with serial liver function tests in 3 months
C. Referral to medical oncology for consideration of systemic chemotherapy
D. Laparoscopic cholecystectomy for suspected biliary dyskinesia
E. Percutaneous liver biopsy for histological diagnosis
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents to the ED with left lower quadrant abdominal pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed. Based on the image, what is the most appropriate next step in management?

A. Increase dietary fiber intake
B. Surgical resection of the affected bowel segment
C. Flexible sigmoidoscopy
D. IV antibiotics and bowel rest
E. Stool culture for C. difficile
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 68-year-old male presents with fatigue, weight loss, and vague abdominal discomfort. His past medical history is significant for a recently diagnosed gastric mixed adenoneuroendocrine carcinoma (MANEC). A CT scan of the abdomen is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. Observation with serial imaging
B. Palliative chemotherapy
C. Liver transplantation
D. Radiofrequency ablation of liver lesions
E. Surgical resection of the primary tumor
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old male with a known history of Blue Rubber Bleb Naevus Syndrome, characterised by recurrent gastrointestinal bleeding and multiple cutaneous vascular lesions, presents to the emergency department with acute onset severe, colicky abdominal pain, nausea, and vomiting. On examination, his abdomen is distended and diffusely tender with reduced bowel sounds. Vital signs are within normal limits. An urgent abdominal CT scan is performed. Based on the clinical presentation and the findings demonstrated in the image, what is the most appropriate immediate next step in management?

A. Initiate broad-spectrum antibiotics for suspected peritonitis
B. Endoscopic evaluation of the small bowel
C. Barium enema for hydrostatic reduction
D. Laparotomy for reduction and resection of affected segments
E. Conservative management with nasogastric tube decompression and observation
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Neuroblastoma, CT of the abdomen
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A 3-year-old presents with abdominal distension, irritability, and periorbital ecchymosis. Examination reveals a firm, irregular abdominal mass. The provided image is an axial CT slice. Considering the clinical presentation and the findings demonstrated in the image, which of the following biochemical markers is MOST likely to be significantly elevated?

A. Serum CA-125
B. Urinary metanephrines
C. Urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA)
D. Serum alpha-fetoprotein (AFP)
E. Serum lactate dehydrogenase (LDH)
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 35-year-old male presents with a two-month history of fatigue, unintentional weight loss, and a persistent dry cough. He denies fever or night sweats. A PET-CT scan of the chest was performed (image shown). What is the MOST appropriate next step in management?

A. Repeat PET-CT in 3 months
B. Initiate anti-tuberculosis therapy
C. Bronchoscopy with biopsy
D. Empiric antibiotic therapy
E. Sputum culture for bacterial pathogens
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with fever (38.2°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His blood pressure is 130/80 mmHg, heart rate 85 bpm, respiratory rate 16 bpm. Blood tests show a white cell count of 14 x 10^9/L and CRP 80 mg/L. A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's presentation and the findings on the provided image, which of the following is the most appropriate initial management strategy?

A. Intravenous antibiotics and hospital admission
B. Urgent surgical consultation for sigmoid colectomy
C. Oral antibiotics and outpatient management
D. Repeat CT scan in 24 hours to assess for progression
E. Immediate colonoscopy to assess the extent of disease
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old patient with a long history of recurrent gastrointestinal bleeding and multiple cutaneous vascular lesions presents with acute onset severe abdominal pain, nausea, and distension. Physical examination reveals a distended, mildly tender abdomen. Bowel sounds are reduced. Vital signs are stable. Imaging is performed. Considering the patient's presentation and the findings demonstrated in the image, which of the following represents the most appropriate initial management approach?

A. Urgent upper and lower endoscopy to identify bleeding source.
B. Initiation of systemic medical therapy targeting vascular malformations.
C. Further imaging with mesenteric angiography.
D. Laparotomy for reduction or resection of affected bowel segments.
E. Non-operative management with nasogastric tube decompression and intravenous fluids.
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old man presents with a 4-month history of increasing constipation alternating with loose stools, occasional rectal bleeding, and fatigue. He denies significant weight loss. Physical examination is unremarkable. Full blood count shows a haemoglobin of 115 g/L with low ferritin. A colonoscopy was performed, and the image provided is a representative view. Biopsies were taken from the observed lesion. Considering the clinical presentation and the endoscopic finding, what is the most appropriate next investigation to determine the extent of disease and inform definitive management planning?

A. PET scan
B. CT scan of chest, abdomen, and pelvis
C. Bone scan
D. Endoscopic ultrasound
E. MRI of the pelvis
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A 58-year-old woman presents with a 7-year history of chronic cough productive of copious, often purulent, sputum, particularly noticeable in the mornings. She reports requiring 4-5 courses of antibiotics annually for exacerbations of her 'chronic bronchitis'. She is a non-smoker and has no significant past medical history other than childhood measles complicated by pneumonia. On examination, she has scattered coarse crackles bilaterally at the lung bases. Her oxygen saturation is 96% on room air. Spirometry performed 3 months ago showed FEV1 78% predicted, FVC 85% predicted, FEV1/FVC 0.75. A recent chest X-ray was reported as showing 'mild peribronchial thickening'. Given the clinical suspicion, what is the single most appropriate next investigation to establish the diagnosis?

A. Bronchoscopy with bronchoalveolar lavage
B. Sputum culture for bacteria, fungi, and mycobacteria
C. Alpha-1 antitrypsin level
D. High-resolution computed tomography (HRCT) of the chest
E. Pulmonary function tests including lung volumes and diffusion capacity
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

An asymptomatic 70-year-old male undergoes a CT scan of the abdomen as part of an investigation for mild, intermittent lower back pain. His vital signs are stable, and physical examination is unremarkable. Considering the findings on the provided image, what is the most appropriate next step in this patient's management?

A. No further imaging required; manage back pain symptomatically.
B. Annual abdominal ultrasound surveillance.
C. Urgent referral for vascular surgical assessment.
D. Referral for a follow-up CT angiogram in 2 years.
E. Repeat CT scan in 6 months.
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