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elderly patient

Practice targeted AMC-style multiple-choice questions on elderly patient.

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A 72-year-old woman is admitted to the hospital with increasing confusion and generalized weakness over the past week. Her medical history includes hypertension, for which she takes hydrochlorothiazide 25mg daily. On examination, she is lethargic and disoriented. Her blood pressure is 110/70 mmHg, heart rate is 88 bpm, and respiratory rate is 16 breaths per minute. Neurological examination reveals decreased reflexes. Initial laboratory investigations reveal the following: Sodium: 118 mmol/L Potassium: 3.8 mmol/L Chloride: 85 mmol/L Bicarbonate: 24 mmol/L Blood Urea Nitrogen (BUN): 25 mg/dL Creatinine: 1.1 mg/dL Glucose: 95 mg/dL Urine osmolality is 600 mOsm/kg. Serum osmolality is 250 mOsm/kg. Which of the following is the most appropriate initial management strategy?

A. Initiation of desmopressin (DDAVP) therapy to reduce free water excretion.
B. Administration of intravenous hypertonic saline (3% NaCl) at a rate of 50 mL/hour.
C. Administration of a loop diuretic (e.g., furosemide) to promote free water excretion.
D. Administration of intravenous normal saline (0.9% NaCl) at a rate of 100 mL/hour.
E. Fluid restriction to 800-1000 mL/day and monitoring of serum sodium levels every 4-6 hours.
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 68-year-old male with known Hepatitis B related cirrhosis and a history of alcohol excess presents for routine surveillance. His alpha-fetoprotein (AFP) level, which has been stable at 15 ng/mL for the past two years, is now noted to be 185 ng/mL. A screening ultrasound performed three months prior was reported as showing diffuse parenchymal changes consistent with cirrhosis but no focal lesions. Due to the elevated AFP, a repeat ultrasound was performed, which identified a 2.5 cm nodule in segment VIII. To further characterise this lesion, a contrast-enhanced ultrasound (CEUS) was performed, and the images provided are representative findings from this study. The patient has well-compensated cirrhosis (Child-Pugh A) and no significant comorbidities. His liver function tests are within normal limits except for a slightly elevated GGT. Given the clinical context and the findings demonstrated in the provided images, what is the most appropriate next step in the management of this patient?

A. Discuss the case in a multidisciplinary team meeting to determine suitability for curative therapy.
B. Perform a core needle biopsy of the lesion for histological confirmation.
C. Proceed directly to surgical resection of the lesion.
D. Repeat the contrast-enhanced ultrasound in 3 months.
E. Initiate systemic chemotherapy with Sorafenib.
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with abdominal distension, obstipation, and vomiting. He has a history of prior abdominal surgery. An upright abdominal X-ray is performed. What is the MOST appropriate next step in management?

A. Colonoscopy
B. Surgical consultation
C. Barium enema
D. Stool softeners
E. Oral antibiotics
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A 65-year-old man with a Popeye deformity has persistent pain and weakness despite conservative management. What is the next step?

A. Refer for surgical repair.
B. Observe for 6 months.
C. Order an MRI.
D. Start physical therapy.
E. Prescribe NSAIDs.
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for follow-up after experiencing intermittent episodes of right upper quadrant colicky pain over the past year, which have since resolved. She denies any current pain, fever, jaundice, or changes in bowel habits. Physical examination is unremarkable, and recent liver function tests are within normal limits. An elective abdominal ultrasound was performed, yielding the image shown. Considering the clinical context and the findings demonstrated, what is the most appropriate next step in her management?

A. Discharge with advice to return if symptoms recur
B. ERCP for stone extraction
C. Initiate ursodeoxycholic acid therapy
D. MRCP to further delineate the biliary anatomy
E. Elective laparoscopic cholecystectomy
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A 70-year-old man with severe COPD (FEV1 30% predicted), on triple inhaled therapy and supplemental oxygen, presents with a 3-day history of increased dyspnoea, productive cough with purulent sputum, and reduced exercise tolerance. He denies fever or chest pain. On examination, he is tachypnoeic (RR 24), saturating 88% on 2 L/min oxygen, with diffuse wheeze and prolonged expiration. His chest X-ray shows hyperinflation but no new infiltrates. His arterial blood gas on 2 L/min oxygen shows pH 7.32, pCO2 68 mmHg, pO2 55 mmHg, bicarbonate 35 mmol/L. Given this presentation, what is the most appropriate immediate management step?

A. Initiate non-invasive ventilation
B. Prescribe oral antibiotics
C. Administer intravenous corticosteroids
D. Increase supplemental oxygen flow rate
E. Perform a bronchoscopy
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A 68-year-old man presents to the emergency department with 90 minutes of crushing chest pain radiating to his left arm. He is diaphoretic and anxious. ECG shows 3mm ST elevation in leads V2-V4. His blood pressure is 130/80 mmHg, heart rate 75 bpm. What is the most appropriate immediate next step in management?

A. Arrange urgent coronary CT angiography
B. Administer dual antiplatelet therapy and heparin
C. Prepare for intravenous fibrinolysis
D. Activate the cardiac catheterisation laboratory for primary PCI
E. Obtain serial cardiac biomarkers
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension presents with a severe headache and altered mental status. Aneurysm coiling was performed. The image shows a post-operative angiogram. 6 hours later, she develops a fever of 38.5°C and worsening neurological deficits. What is the MOST likely cause?

A. Meningitis
B. Coil migration
C. Hemorrhagic conversion
D. Hydrocephalus
E. Vasospasm
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A 60-year-old woman presents to her GP with a 3-month history of fatigue, weight gain, and feeling cold all the time. She also reports constipation and dry skin. On examination, she has a slow heart rate and her skin appears dry and coarse. What is the most appropriate initial investigation?

A. Serum TSH level
B. Complete blood count
C. Serum cortisol level
D. Liver function tests
E. Serum calcium level
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A 72-year-old retired builder with a 50 pack-year smoking history presents with a 3-month history of worsening cough, occasional streaks of blood in sputum, and unintentional weight loss of 6 kg. He reports mild dyspnoea on exertion, able to climb one flight of stairs before needing to rest. On examination, he is thin but alert, with an ECOG performance status of 1. Chest auscultation reveals decreased breath sounds over the right upper zone. A chest X-ray shows a 4.5 cm spiculated mass in the right upper lobe. There is no obvious pleural effusion or mediastinal widening. Full blood count, electrolytes, liver function tests, and renal function tests are within normal limits, except for a haemoglobin of 115 g/L. Spirometry shows FEV1 65% predicted, FVC 80% predicted, FEV1/FVC ratio 0.7.

A. Bronchoscopy with biopsy and endobronchial ultrasound (EBUS) for mediastinal staging.
B. Pulmonary function tests including DLCO.
C. Mediastinoscopy for nodal biopsy.
D. CT-guided core biopsy of the mass.
E. PET-CT scan for whole-body staging.
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 68-year-old male with known Hepatitis B related cirrhosis and a history of alcohol excess presents for routine surveillance. His alpha-fetoprotein (AFP) level, which has been stable at 15 ng/mL for the past two years, is now noted to be 185 ng/mL. A screening ultrasound performed three months prior was reported as showing diffuse parenchymal changes consistent with cirrhosis but no focal lesions. Due to the elevated AFP, a repeat ultrasound was performed, which identified a 2.5 cm nodule in segment VIII. To further characterise this lesion, a contrast-enhanced ultrasound (CEUS) was performed, and the images provided are representative findings from this study. The patient has well-compensated cirrhosis (Child-Pugh A) and no significant comorbidities. His liver function tests are within normal limits except for a slightly elevated GGT. Given the clinical context and the findings demonstrated in the provided images, what is the most appropriate next step in the management of this patient?

A. Referral to a multidisciplinary liver tumour board for consideration of curative treatment options.
B. Proceed directly to percutaneous biopsy of the lesion for histological confirmation.
C. Refer the patient to a general gastroenterologist for further investigation.
D. Initiate systemic therapy with a tyrosine kinase inhibitor such as sorafenib.
E. Schedule a repeat contrast-enhanced ultrasound in three months to assess for interval change.
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 68-year-old woman presents to her GP with a 3-month history of a persistent, mildly pruritic skin lesion on her left chest wall. She had a left simple mastectomy for invasive ductal carcinoma 10 years ago, followed by adjuvant therapy. She denies fever, weight loss, or other systemic symptoms. Physical examination reveals the appearance shown. What is the most appropriate initial diagnostic investigation?

A. Prescribe a course of topical antifungal cream
B. Punch biopsy of the lesion
C. Order a PET-CT scan for staging
D. Arrange a follow-up appointment in 3 months to monitor the lesion
E. Perform a shave biopsy of the lesion
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 68-year-old female presents with right leg pain and skin changes after starting warfarin for atrial fibrillation 5 days ago. Her INR is currently 3.5. Examination reveals the findings in the image. What is the MOST appropriate next step in management?

A. Apply compression bandages and elevate the leg
B. Start heparin and continue warfarin at the same dose
C. Reduce warfarin dose and monitor INR daily
D. Stop warfarin and administer vitamin K and fresh frozen plasma
E. Continue warfarin at the same dose and apply topical corticosteroids
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman with osteoporosis and a history of kidney stones presents with a serum calcium of 2.9 mmol/L (2.1-2.6 mmol/L) and PTH of 120 pg/mL (10-65 pg/mL). She denies neck pain or swelling. The provided imaging was obtained. What is the MOST appropriate next step?

A. Cinacalcet to lower PTH levels
B. Vitamin D and calcium supplementation
C. Surgical excision of the identified lesion
D. Bisphosphonate therapy and observation
E. Thyroidectomy
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for routine follow-up. He is asymptomatic. Review the image. What is the most appropriate next step in management?

A. Commence dual antiplatelet therapy
B. Repeat imaging in 6-12 months
C. Prescribe a statin
D. Initiate beta-blocker therapy
E. Schedule elective surgical repair
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 65-year-old male presents with a 3-month history of unintentional weight loss and early satiety. Gastroscopy and biopsy confirmed a gastric mixed adenoneuroendocrine carcinoma. Staging CT imaging is shown. Considering the clinical presentation and the findings on the provided imaging, what is the most appropriate initial management strategy?

A. Commence somatostatin analogue therapy.
B. Proceed with surgical resection of hepatic lesions.
C. Monitor with serial CT scans and symptomatic management.
D. Initiate systemic chemotherapy.
E. Plan for palliative external beam radiotherapy to the liver.
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 63-year-old woman with a 20-year history of Crohn's disease presents with worsening abdominal pain, bloating, and occasional post-prandial vomiting. She is currently managed with mesalazine and budesonide. Physical examination reveals mild right lower quadrant tenderness. Laboratory tests show a slightly elevated CRP. Given her presentation and the provided imaging, what is the most appropriate next step in her management?

A. Perform an urgent colonoscopy with biopsies
B. Increase the dose of budesonide
C. Continue current medical therapy and monitor symptoms
D. Switch mesalazine to an oral corticosteroid like prednisone
E. Refer for surgical assessment for potential stricture or complication
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old man with a history of cholelithiasis presents with a 2-day history of fever, jaundice, and severe right upper quadrant pain. His vital signs are stable, but laboratory tests show elevated bilirubin and alkaline phosphatase. He is undergoing urgent ERCP for management of suspected choledocholithiasis and cholangitis. Following successful cannulation and injection of contrast, the image is obtained. Considering the findings demonstrated in the image in the context of this patient's presentation, what is the most appropriate immediate next step during this procedure?

A. Placement of a biliary stent
B. Mechanical lithotripsy
C. Balloon dilation of the common bile duct
D. Endoscopic sphincterotomy
E. Attempt stone extraction with a basket
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A 70-year-old male presents to the emergency department with severe abdominal and back pain. He has a history of hypertension and smoking. On examination, he is hypotensive and tachycardic. Palpation reveals a pulsatile abdominal mass. What is the most likely diagnosis?

A. Ruptured abdominal aortic aneurysm
B. Renal colic
C. Acute pancreatitis
D. Myocardial infarction
E. Diverticulitis
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 70-year-old male with ascending cholangitis undergoes ERCP. The image is obtained. What is the MOST appropriate next step in management?

A. Ursodeoxycholic acid administration
B. Sphincterotomy and stone extraction
C. Observation with serial LFTs
D. Percutaneous transhepatic biliary drainage
E. Cholecystectomy
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A 60-year-old non-smoker has a calculated 5-year cardiovascular disease risk of 12%. Based on current Australian guidelines, what is the most appropriate initial management focus?

A. Annual risk reassessment without intervention
B. Lifestyle modification and shared decision-making regarding pharmacotherapy
C. Immediate initiation of high-intensity statin therapy
D. Referral for specialist cardiology review
E. Low-dose aspirin therapy for primary prevention
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old male with acute cholangitis is undergoing ERCP for stone extraction. The image is obtained after cannulation. Based on the findings, what is the most appropriate immediate next step in the procedure?

A. Insert nasobiliary drain
B. Terminate procedure and give antibiotics
C. Attempt basket extraction
D. Endoscopic sphincterotomy
E. Perform mechanical lithotripsy
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 70-year-old male with known gastric MANEC presents with worsening jaundice and ascites. The provided CT scan was performed. Which of the following serum markers would be MOST useful in monitoring disease progression in this patient?

A. Amylase
B. Chromogranin A
C. CEA
D. Alpha-fetoprotein
E. CA 19-9
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 62-year-old man presents to his GP with a history of a bulge in his right groin that has been present for approximately 18 months. He reports it is more prominent with straining or standing and disappears completely when he lies down. He denies any associated pain, nausea, vomiting, or change in bowel habits. He has no significant past medical history. His physical examination reveals the finding depicted in the image. Vital signs are within normal limits. Based on this clinical picture, which of the following represents the most appropriate definitive management strategy for this patient?

A. Observation with regular follow-up.
B. Urgent surgical exploration.
C. Further imaging to confirm the diagnosis.
D. Elective surgical repair.
E. Non-surgical management with a supportive device.
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old presents with acute cholangitis (fever, jaundice, RUQ pain). LFTs show obstructive pattern. ERCP is performed for biliary decompression and stone extraction. Following successful cannulation and cholangiography, the image is obtained. Based on the findings demonstrated in the image, what is the most appropriate immediate next step during this procedure?

A. Terminate the procedure and schedule surgery
B. Attempt stone extraction with a balloon catheter
C. Administer intravenous antibiotics and observe
D. Perform a sphincterotomy
E. Insert a biliary stent
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A 68-year-old man with hypertension presents with sudden onset right-sided weakness and slurred speech. GCS is 13. BP 190/110 mmHg. What is the most critical initial investigation to guide management?

A. CT angiography
B. Lumbar puncture
C. Non-contrast CT head
D. ECG
E. MRI brain
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An elderly man presents with a 6-month history of memory decline, recurrent falls, visual hallucinations, agitation, and confusion. His wife reports he talks to people who are not visible. Which of the following clinical features is most helpful in diagnosing his condition?

A. Nystagmus
B. Parkinsonian gait/tremor
C. Ataxia
D. Aphasia
E. Hemiparesis
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 68-year-old male with a history of chronic hepatitis C presents to the clinic complaining of right upper quadrant abdominal pain and unintentional weight loss of 10 kg over the past 6 months. His past medical history is significant for well-controlled hypertension and hyperlipidemia. Physical examination reveals mild hepatomegaly. Laboratory investigations show elevated alpha-fetoprotein (AFP) levels. A contrast-enhanced ultrasound of the liver is performed, and representative images are shown. Based on the imaging and clinical context, which of the following is the MOST appropriate next step in management?

A. Radiofrequency ablation of the lesion
B. Surveillance with serial AFP measurements and ultrasound every 3 months
C. Surgical resection of the lesion
D. Initiation of systemic chemotherapy with sorafenib
E. Referral for liver biopsy to confirm diagnosis and assess grade
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

An 82-year-old woman with a history of paroxysmal atrial fibrillation and a recent hospitalisation for pneumonia was discharged 5 days ago on warfarin 5mg daily. She presents to the emergency department complaining of increasing pain and a rapidly evolving lesion on her right lower leg over the past 48 hours. She denies trauma. Her vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, Temp 36.8°C. Physical examination reveals the appearance shown in the image on her right anterior lower leg. Her INR today is 4.5. She has no known history of protein C or S deficiency. Considering the patient's history, current medication, laboratory result, and the clinical appearance depicted, which of the following represents the most appropriate immediate management strategy?

A. Prescribe oral flucloxacillin and review in 24 hours for suspected bacterial cellulitis.
B. Increase the daily dose of warfarin to achieve a target INR of 2.5-3.0 more rapidly.
C. Arrange for urgent surgical consultation for debridement of the necrotic tissue.
D. Discontinue warfarin, administer intravenous vitamin K, and initiate therapeutic dose unfractionated heparin or low molecular weight heparin.
E. Switch warfarin to rivaroxaban 20mg daily and monitor the lesion.
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A 67-year-old woman presents to her GP with fatigue, weight loss, and night sweats over the past two months. She has a history of smoking and hypertension. On examination, she has palpable lymphadenopathy in the cervical and axillary regions. Blood tests reveal a hemoglobin level of 10 g/dL, elevated lactate dehydrogenase (LDH), and a peripheral blood smear showing atypical lymphocytes. What is the most likely diagnosis?

A. Non-Hodgkin's lymphoma
B. Multiple myeloma
C. Hodgkin's lymphoma
D. Chronic lymphocytic leukemia (CLL)
E. Acute myeloid leukemia (AML)
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

Mr. Arthur Jenkins, a 72-year-old retired accountant, presents to his GP complaining of a change in bowel habit over the past 4 months, now experiencing increased frequency and occasional loose stools mixed with some mucus. He also reports intermittent small amounts of bright red blood on the toilet paper, which he initially attributed to haemorrhoids. He denies significant weight loss or abdominal pain. His past medical history includes hypertension well-controlled on medication and osteoarthritis. On examination, his abdomen is soft and non-tender, and digital rectal examination is unremarkable. Routine blood tests, including FBE and LFTs, are within normal limits. A faecal occult blood test is positive. Given these findings, a colonoscopy is arranged. The image provided was captured during the procedure. Considering the patient's presentation and the findings observed during the colonoscopy as depicted in the image, what is the most appropriate immediate next step in the management plan?

A. Attempt endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) of the lesion.
B. Advise the patient on dietary modifications to increase fibre intake and schedule a follow-up appointment in 3 months.
C. Prescribe a course of antibiotics for presumed infectious colitis and repeat colonoscopy in 6 weeks.
D. Refer the patient directly for urgent surgical consultation for a potential sigmoid colectomy.
E. Obtain multiple biopsies from the lesion for histological examination and arrange for CT staging of the chest, abdomen, and pelvis.
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A 65-year-old man with a history of COPD presents with fever, productive cough, and shortness of breath for 3 days. On examination, he has crackles in the right lower lung field. A chest X-ray shows a right lower lobe consolidation. What is the most likely diagnosis?

A. Tuberculosis
B. Lung cancer
C. Heart failure
D. Pulmonary embolism
E. Community-acquired pneumonia
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A 72-year-old woman is admitted to the hospital with increasing confusion and generalized weakness over the past week. Her medical history includes hypertension, for which she takes hydrochlorothiazide 25mg daily. On examination, she is lethargic but arousable. Her blood pressure is 110/70 mmHg, heart rate is 88 bpm, and respiratory rate is 16 breaths per minute. Neurological examination reveals decreased reflexes. Initial laboratory investigations reveal the following: Sodium 118 mmol/L, Potassium 3.8 mmol/L, Chloride 85 mmol/L, Bicarbonate 24 mmol/L, BUN 15 mg/dL, Creatinine 0.8 mg/dL, Glucose 90 mg/dL. Urine osmolality is 600 mOsm/kg. Serum osmolality is 250 mOsm/kg. Which of the following is the most appropriate initial management strategy?

A. Fluid restriction and monitoring of sodium levels
B. Administration of desmopressin (DDAVP)
C. Administration of intravenous normal saline at a rapid infusion rate
D. Administration of a loop diuretic such as furosemide
E. Administration of intravenous 3% hypertonic saline at a rate of 50 mL/hour
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A 70-year-old man with a history of atrial fibrillation presents with sudden onset of severe pain, pallor, and coldness in his left leg, extending below the knee. On examination, the leg is cool to touch, pale, and distal pulses (popliteal, dorsalis pedis, posterior tibial) are absent. Sensation is diminished below the ankle, but he can still move his toes slightly. Capillary refill is delayed. Which of the following is the most appropriate initial diagnostic investigation?

A. Arterial duplex ultrasound of the affected limb
B. Venous duplex ultrasound of the affected limb
C. CT angiography of the affected limb
D. Plain film X-ray of the affected limb
E. ECG and cardiac enzymes
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A 72-year-old man with fatigue, a past myocardial infarction at age 55, breathlessness on stairs, and ankle marks has an LVEF < 40% on echocardiogram. Which of the following medications is known to improve outcomes in Heart Failure with Reduced Ejection Fraction (HFrEF)?

A. Digoxin
B. Verapamil
C. Frusemide
D. Amlodipine
E. Eplerenone
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A 72-year-old man with a history of hypertension and type 2 diabetes mellitus is being managed with lisinopril. He presents to the emergency department complaining of lip swelling and difficulty breathing. On examination, his tongue appears swollen. What is the most appropriate immediate management?

A. Administer intramuscular epinephrine
B. Administer intravenous corticosteroids
C. Administer nebulized bronchodilators
D. Administer intravenous antihistamines
E. Observe and monitor vital signs
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old male presents to his GP complaining of a change in bowel habit over the past 6 months. He reports increasing constipation alternating with episodes of diarrhea. He also mentions unintentional weight loss of approximately 5 kg during this period. He denies any family history of bowel cancer. A colonoscopy was performed, and a representative image is shown. Assuming the lesion is confirmed as malignant, what is the MOST appropriate next step in the management of this patient?

A. Referral for palliative care
B. Repeat colonoscopy in 3 years
C. CT scan of the chest, abdomen, and pelvis
D. Initiate adjuvant chemotherapy with FOLFOX
E. Administer a course of broad-spectrum antibiotics
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old male presents with worsening headaches and blurred vision 3 months post-embolization. The attached image was obtained. Which of the following is the MOST appropriate next step in management?

A. Order an MRI of the brain to rule out other causes of headache
B. Initiate a course of high-dose corticosteroids
C. Refer for surgical clipping of the aneurysm
D. Repeat angiography to assess for recanalization
E. Prescribe analgesics and schedule a follow-up appointment in 6 months
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

An 80-year-old male with a history of smoking and hypertension presents to his GP with mild, intermittent lower back pain. Physical examination is unremarkable. Routine blood tests are normal. A CT scan of the abdomen is performed to investigate the back pain. Considering the findings demonstrated in the provided image in the context of this patient's presentation, what is the most appropriate next step in management?

A. Refer immediately for surgical consultation for elective repair.
B. Initiate aggressive blood pressure control and repeat imaging in 5 years.
C. Schedule regular surveillance imaging.
D. Perform urgent angiography to assess for rupture risk.
E. Discharge with advice to return if pain worsens significantly.
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old woman with a history of hypertension and hyperlipidemia presents to the emergency department with a sudden onset of left-sided hemianopia and mild right-sided weakness. Her symptoms began approximately 4 hours prior to arrival. Initial neurological examination reveals a left homonymous hemianopia, mild right hemiparesis (4/5 strength), and intact sensation. A CT angiogram was performed, and the patient underwent endovascular coiling. The image shows a follow-up angiogram post-procedure. Despite the intervention, the patient's left homonymous hemianopia persists, and her right hemiparesis has not improved. What is the MOST appropriate next step in the management of this patient?

A. Repeat angiography to assess for recanalization or further aneurysm growth
B. Start rehabilitation therapy and monitor for improvement
C. Order an MRI of the brain to evaluate for ischemic changes
D. Prescribe a course of high-dose corticosteroids to reduce peri-aneurysmal edema
E. Initiate dual antiplatelet therapy with aspirin and clopidogrel
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A 75-year-old man with type 2 diabetes and chronic kidney disease presents with a 3-day history of productive cough, fever, and pleuritic chest pain. On examination, temperature is 38.2°C, HR 105, BP 130/80, RR 22, SpO2 93% on air. Crackles are heard over the right lower lung field. Which initial investigation is most crucial for guiding management?

A. Arterial blood gas
B. Blood cultures
C. Full blood count and C-reactive protein
D. Sputum culture and sensitivity
E. Chest X-ray
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 68-year-old male presents to the emergency department complaining of acute onset shortness of breath and right-sided chest pain. He reports that the pain started suddenly this morning and has been gradually worsening. He has a history of paroxysmal atrial fibrillation, for which he takes warfarin. He denies any recent trauma or injury. On examination, his vital signs are: heart rate 115 bpm, blood pressure 95/60 mmHg, respiratory rate 30 breaths per minute, oxygen saturation 87% on room air. Auscultation reveals decreased breath sounds on the right side. The patient appears pale and is diaphoretic. His INR is 6.5. A CT scan of the chest is performed, and the relevant image is shown. What is the MOST appropriate next step in the management of this patient?

A. Perform needle thoracostomy followed by insertion of an underwater seal drain
B. Administer intravenous protamine sulfate and monitor for improvement in respiratory status
C. Administer intravenous furosemide and monitor urine output
D. Insert a chest tube and administer intravenous vitamin K and prothrombin complex concentrate (PCC)
E. Administer intravenous antibiotics and schedule a repeat CT scan in 24 hours
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman reports past episodes of transient right upper quadrant pain, now resolved. She is currently asymptomatic with normal liver function tests. An abdominal ultrasound was performed as part of her evaluation. Based on the findings from this imaging study and her clinical history, what is the most appropriate management recommendation?

A. Medical dissolution therapy with ursodeoxycholic acid
B. Observation and symptomatic management as needed
C. Magnetic resonance cholangiopancreatography (MRCP) for further evaluation
D. Endoscopic retrograde cholangiopancreatography (ERCP) for stone extraction
E. Elective cholecystectomy
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old man presents to the emergency department with a 2-day history of worsening left lower quadrant abdominal pain, associated with fever and chills. He reports a change in bowel habit with increased constipation. On examination, he is febrile at 38.6°C and has significant tenderness and guarding in the left iliac fossa. His white cell count is 18 x 10^9/L. A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's presentation and the findings on the provided image, which of the following represents the most appropriate initial management strategy?

A. Prescribe oral antibiotics and advise outpatient follow-up with his general practitioner.
B. Schedule an urgent colonoscopy to assess the extent of the disease process.
C. Initiate intravenous broad-spectrum antibiotics and arrange hospital admission for monitoring.
D. Provide analgesia and antiemetics, and discharge home with instructions to return if symptoms worsen.
E. Arrange urgent surgical review for consideration of immediate operative intervention.
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old man presents with 3 days of worsening left lower quadrant pain, fever, and nausea. He has a history of diverticulosis. On examination, he is tachycardic (HR 105), afebrile (37.5°C), and has localised tenderness with guarding in the left iliac fossa. His blood tests show a WCC of 16 x 10^9/L and CRP 150 mg/L. He is commenced on intravenous antibiotics. A CT scan is performed (image provided). Considering the clinical context and the findings on the image, what is the most appropriate next step in management?

A. Arrange for percutaneous drainage of the collection.
B. Prepare for urgent surgical resection of the affected bowel segment.
C. Transition to oral antibiotics and discharge home.
D. Request a repeat CT scan in 24 hours to assess for changes.
E. Continue intravenous antibiotics and monitor clinical progress.
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old man presents with a 4-month history of increasing constipation alternating with loose stools, occasional rectal bleeding, and fatigue. He denies significant weight loss. Physical examination is unremarkable. Full blood count shows a haemoglobin of 115 g/L with low ferritin. A colonoscopy was performed, and the image provided is a representative view. Biopsies were taken from the observed lesion. Considering the clinical presentation and the endoscopic finding, what is the most appropriate next investigation to determine the extent of disease and inform definitive management planning?

A. PET scan
B. CT scan of chest, abdomen, and pelvis
C. Bone scan
D. Endoscopic ultrasound
E. MRI of the pelvis
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old male presents with acute LLQ pain. The provided image was obtained. What dietary advice is most appropriate upon resolution of acute symptoms?

A. Low-residue diet
B. Gluten-free diet
C. Lactose-free diet
D. Elemental diet
E. High-fibre diet
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 72-year-old woman presents with a 6-month history of a non-healing rash on her chest wall at the site of a previous mastectomy performed 10 years prior for invasive ductal carcinoma. She has completed adjuvant chemotherapy and radiation. Examination reveals the findings shown. What is the MOST appropriate next step in management?

A. Skin biopsy of the affected area
B. Topical corticosteroid application
C. Referral for wide local excision
D. Empiric antibiotic therapy
E. Fungal culture of the lesion
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 65-year-old man presents to the emergency department with a 2-day history of worsening left lower quadrant abdominal pain, associated with fever and chills. He reports a change in bowel habit with increased constipation. On examination, he is febrile at 38.6°C and has significant tenderness and guarding in the left iliac fossa. His white cell count is 18 x 10^9/L. A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's presentation and the findings on the provided image, which of the following represents the most appropriate initial management step in addition to intravenous antibiotics?

A. Percutaneous drainage of the identified collection.
B. Urgent laparoscopic sigmoid colectomy.
C. Close observation with serial abdominal examinations.
D. Commencement of oral metronidazole and discharge home.
E. Flexible sigmoidoscopy to assess mucosal inflammation.
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An 82-year-old man with a history of COPD and mild dementia is brought to the emergency department by his family due to increased confusion over 24 hours. He has had a low-grade fever (37.8°C) and a mild cough for 3 days. On examination, he is drowsy but rousable. His oxygen saturation is 90% on room air. Chest auscultation reveals decreased breath sounds at the bases. A chest X-ray shows bilateral lower lobe infiltrates. His CURB-65 score is 3. Considering the patient's presentation and CURB-65 score, what is the most appropriate initial management plan?

A. Admission to hospital for observation and oral antibiotics.
B. Discharge home with supportive care and review in 24 hours.
C. Admission to ICU for mechanical ventilation and broad-spectrum antibiotics.
D. Outpatient management with oral antibiotics and close follow-up.
E. Admission to hospital with intravenous antibiotics.
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