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elderly patient

Practice targeted AMC-style multiple-choice questions on elderly patient.

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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 72-year-old female presents with right leg pain and skin changes after starting warfarin for atrial fibrillation. Her INR is 3.5. Examination reveals the findings in the image. What is the MOST appropriate next step in management?

A. Administer vitamin K and discontinue warfarin
B. Elevate the leg and apply compression bandages
C. Prescribe a broad-spectrum antibiotic
D. Apply topical corticosteroids
E. Increase the dose of warfarin
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A 72-year-old woman is admitted to the hospital with increasing confusion and generalized weakness over the past week. Her medical history includes hypertension, for which she takes hydrochlorothiazide 25mg daily. On examination, she is lethargic and disoriented. Her blood pressure is 110/70 mmHg, heart rate is 88 bpm, and respiratory rate is 16 breaths per minute. Neurological examination reveals decreased reflexes. Initial laboratory investigations reveal the following: Sodium: 118 mmol/L Potassium: 3.8 mmol/L Chloride: 85 mmol/L Bicarbonate: 24 mmol/L Blood Urea Nitrogen (BUN): 25 mg/dL Creatinine: 1.1 mg/dL Glucose: 95 mg/dL Urine osmolality is 600 mOsm/kg. Serum osmolality is 250 mOsm/kg. Which of the following is the most appropriate initial management strategy?

A. Initiation of desmopressin (DDAVP) therapy to reduce free water excretion.
B. Administration of intravenous hypertonic saline (3% NaCl) at a rate of 50 mL/hour.
C. Administration of a loop diuretic (e.g., furosemide) to promote free water excretion.
D. Administration of intravenous normal saline (0.9% NaCl) at a rate of 100 mL/hour.
E. Fluid restriction to 800-1000 mL/day and monitoring of serum sodium levels every 4-6 hours.
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A 68-year-old man with a 40 pack-year smoking history presents with a 3-month history of persistent cough, occasional haemoptysis, and a 5 kg weight loss. A chest X-ray shows a left upper lobe opacity. A subsequent CT scan of the chest, abdomen, and pelvis confirms a 4 cm mass in the left upper lobe and identifies several enlarged mediastinal lymph nodes (largest 1.5 cm). There is no clear evidence of distant metastatic disease on the CT scan. He has no neurological symptoms or bone pain. Pulmonary function tests are pending. What is the most appropriate next investigation for staging this patient's non-small cell lung cancer?

A. Brain MRI
B. Bone scan
C. Mediastinoscopy
D. PET-CT scan
E. Repeat CT scan in 3 months
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CT, ultrasonography, SPECT and scintigraphy of intra-thyroid parathyroid adenoma
Image by Mnahi Bin Saeedan, Ibtisam Musallam Aljohani, Ayman Omar Khushaim, Salwa Qasim Bukhari, Salahudin Tayeb Elnaas CC BY 4.0 · Source

A 62-year-old woman presents to her GP with a 6-month history of increasing fatigue, generalised bone aches, and constipation. She has no significant past medical history and takes no regular medications. Physical examination is unremarkable. Initial laboratory investigations reveal a corrected serum calcium level of 3.1 mmol/L (reference range: 2.1-2.6 mmol/L) and an elevated parathyroid hormone (PTH) level of 180 pg/mL (reference range: 10-65 pg/mL). A 24-hour urine calcium excretion is 12 mmol/day (reference range: 2.5-7.5 mmol/day). She is referred for further imaging, the results of which are shown. Based on the available information, what is the MOST appropriate next step in the management of this patient?

A. Order genetic testing for MEN syndromes
B. Surgical parathyroidectomy
C. Repeat parathyroid localisation imaging
D. Initiate medical therapy with cinacalcet
E. Perform a bone mineral density scan
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 72-year-old woman, status post mastectomy, presents with a lesion. What is the MOST appropriate initial diagnostic test?

A. Patch testing
B. Skin biopsy
C. Wood's lamp examination
D. KOH examination
E. Fungal culture
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 70-year-old male with cirrhosis secondary to alcohol abuse presents with new-onset ascites and a palpable liver mass. His AFP is markedly elevated. A contrast-enhanced ultrasound is performed, as shown. What is the MOST appropriate next diagnostic step?

A. Quadruple-phase CT scan of the abdomen
B. Initiate systemic chemotherapy
C. Repeat ultrasound in 3 months
D. MRI of the abdomen with hepatobiliary contrast
E. Liver biopsy
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A 70-year-old man with severe COPD (FEV1 30% predicted), on triple inhaled therapy and supplemental oxygen, presents with a 3-day history of increased dyspnoea, productive cough with purulent sputum, and reduced exercise tolerance. He denies fever or chest pain. On examination, he is tachypnoeic (RR 24), saturating 88% on 2 L/min oxygen, with diffuse wheeze and prolonged expiration. His chest X-ray shows hyperinflation but no new infiltrates. His arterial blood gas on 2 L/min oxygen shows pH 7.32, pCO2 68 mmHg, pO2 55 mmHg, bicarbonate 35 mmol/L. Given this presentation, what is the most appropriate immediate management step?

A. Initiate non-invasive ventilation
B. Prescribe oral antibiotics
C. Administer intravenous corticosteroids
D. Increase supplemental oxygen flow rate
E. Perform a bronchoscopy
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Post-embolization arteriogram showing coiled aneurysm (indicated by yellow arrows) of the posteriorcerebral artery with a residual aneurysmal sac.
Image by Promod Pillai, Aftab Karim, Anil Nanda CC BY 2.0 · Source

A 68-year-old male presents with worsening headaches and blurred vision. He underwent endovascular coiling for a posterior cerebral artery aneurysm 6 months ago. The attached image was obtained. Which of the following is the MOST appropriate next step in management?

A. Increase the dose of his antihypertensive medication
B. Initiate aspirin therapy
C. Repeat angiography
D. Order a CT scan of the head without contrast
E. Reassure the patient and schedule a follow-up appointment in 6 months
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for review in the outpatient clinic. She reports a history of intermittent, self-resolving episodes of right upper quadrant colicky pain over the past year, but is currently asymptomatic. She denies fever, jaundice, or other systemic symptoms. Her physical examination is unremarkable, and recent liver function tests are within the normal reference range. An elective abdominal ultrasound was performed, yielding the image shown. Based on the clinical presentation and the findings demonstrated, what is the most appropriate next step in her management?

A. Trial of ursodeoxycholic acid
B. Reassurance and discharge with advice to return if symptoms recur
C. Elective laparoscopic cholecystectomy
D. Further investigation with CT abdomen
E. Referral for endoscopic retrograde cholangiopancreatography (ERCP)
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents to his general practitioner for a routine check-up. He reports a history of hypertension, hyperlipidemia, and a 40-pack-year smoking history. He denies any abdominal pain, back pain, or lower extremity claudication. On physical examination, his vital signs are within normal limits. Auscultation of the abdomen is unremarkable, and peripheral pulses are palpable and symmetric. As part of his cardiovascular risk assessment, a contrast-enhanced CT scan of the abdomen and pelvis is performed. An axial view from the scan is shown. Based on the image and the patient's clinical presentation, which of the following is the MOST appropriate next step in management?

A. Prescribe a beta-blocker to reduce blood pressure and heart rate
B. Schedule a repeat CT scan in 6-12 months to monitor aneurysm size
C. Refer to vascular surgery for elective repair
D. Order an ultrasound of the abdomen to further evaluate the aorta
E. Initiate statin therapy and lifestyle modifications
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 62-year-old man presents with a lesion on his nose that has been slowly enlarging over the past 8 months. He reports occasional tenderness but no bleeding. He has a significant history of outdoor work and multiple previous sunburns. His medical history is otherwise clear. On examination, vital signs are stable. The lesion appears as shown in the image. Regional lymph nodes are not palpable. Considering the clinical presentation and the appearance of the lesion, which of the following is the most appropriate initial step in the management of this patient?

A. Arrange for cryotherapy of the lesion.
B. Perform a punch biopsy of the lesion.
C. Refer immediately for wide local excision.
D. Apply topical imiquimod cream daily.
E. Schedule a follow-up appointment in 3 months to monitor for changes.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for routine follow-up. He is asymptomatic. His past medical history includes hypertension and hyperlipidemia, both well-controlled with medication. Review the provided image. What is the most appropriate next step in management?

A. Prescribe a statin
B. Repeat CT scan in 3 months
C. Referral for immediate surgical repair
D. Annual ultrasound surveillance
E. Initiate beta-blocker therapy
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 78-year-old male on warfarin for atrial fibrillation presents with sudden onset of severe dyspnoea and right-sided pleuritic chest pain. He denies trauma. On examination, he is tachypnoeic, oxygen saturation is 92% on room air. Blood pressure 110/70 mmHg, heart rate 95 bpm. Chest examination reveals decreased breath sounds on the right. A CT scan of the chest is performed. Considering the patient's clinical presentation, medical history, and the findings demonstrated in the provided image, which of the following pharmacological agents is the most appropriate immediate intervention?

A. Fresh frozen plasma (FFP)
B. Vitamin K
C. Tranexamic acid
D. Prothrombinex (PCC)
E. Recombinant Factor VIIa
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A 68-year-old female presents with right leg pain and skin changes after starting warfarin for atrial fibrillation 5 days ago. Her INR is currently 3.5. Examination reveals the findings in the image. What is the MOST appropriate next step in management?

A. Apply compression bandages and elevate the leg
B. Start heparin and continue warfarin at the same dose
C. Reduce warfarin dose and monitor INR daily
D. Stop warfarin and administer vitamin K and fresh frozen plasma
E. Continue warfarin at the same dose and apply topical corticosteroids
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A 68-year-old woman with a history of hypertension and heart failure is admitted to the hospital with increasing shortness of breath and peripheral edema. She is currently taking furosemide 40mg daily. Her blood tests reveal the following: Na+ 130 mmol/L (135-145 mmol/L), K+ 3.1 mmol/L (3.5-5.0 mmol/L), Cl- 95 mmol/L (98-107 mmol/L), HCO3- 32 mmol/L (22-29 mmol/L). What is the most appropriate initial management?

A. Administer intravenous normal saline and continue furosemide at the same dose.
B. Administer an ACE inhibitor and monitor sodium levels.
C. Administer intravenous sodium bicarbonate and increase the dose of furosemide.
D. Hold furosemide, administer intravenous potassium chloride, and restrict free water intake.
E. Administer intravenous calcium gluconate and monitor potassium levels.
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A 68-year-old woman with a history of heart failure presents to the emergency department with increasing shortness of breath and lower extremity edema. She has been taking furosemide 40mg daily for the past year. Her blood pressure is 110/70 mmHg, heart rate is 90 bpm, and respiratory rate is 24 breaths/min. An ECG shows flattened T waves and prominent U waves. Which of the following is the most likely electrolyte abnormality contributing to her presentation?

A. Hypomagnesemia
B. Hypercalcemia
C. Hyperkalemia
D. Hypokalemia
E. Hyponatremia
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 63-year-old woman with a 20-year history of Crohn's disease presents with worsening abdominal pain, bloating, and occasional post-prandial vomiting. She is currently managed with mesalazine and budesonide. Physical examination reveals mild right lower quadrant tenderness. Laboratory tests show a slightly elevated CRP. Given her presentation and the provided imaging, what is the most appropriate next step in her management?

A. Perform an urgent colonoscopy with biopsies
B. Increase the dose of budesonide
C. Continue current medical therapy and monitor symptoms
D. Switch mesalazine to an oral corticosteroid like prednisone
E. Refer for surgical assessment for potential stricture or complication
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A 65-year-old woman presents to her general practitioner with fatigue and pallor. She has a history of rheumatoid arthritis, for which she takes methotrexate and folic acid. She denies any gastrointestinal symptoms or recent changes in her diet. On examination, she appears pale, and her conjunctivae are pale as well. Her blood pressure is 120/75 mmHg, heart rate is 88 bpm, and respiratory rate is 16 breaths per minute. Laboratory investigations reveal hemoglobin of 9.0 g/dL, mean corpuscular volume (MCV) of 105 fL, and normal white blood cell and platelet counts. Which of the following is the most likely cause of her anemia?

A. Iron deficiency anemia
B. Anemia of chronic disease
C. Hemolytic anemia
D. Methotrexate-induced macrocytic anemia
E. Vitamin B12 deficiency
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old woman presents with 3 days of left lower quadrant pain. She reports mild nausea but no vomiting or fever. On examination, she is afebrile, BP 130/80, HR 78, O2 sat 98% on air. There is localised tenderness in the LLQ. Bloods show WCC 13.2, CRP 45. A CT scan is performed. Considering the clinical presentation and the findings demonstrated in the image, what is the most appropriate initial management plan?

A. Discharge with analgesia and advice to return if symptoms worsen, without antibiotics.
B. Outpatient management with oral antibiotics and analgesia.
C. Admission for intravenous antibiotics and observation.
D. Urgent colonoscopy to assess the extent of disease.
E. Surgical consultation for potential colectomy.
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A 70-year-old man with a history of hypertension and type 2 diabetes mellitus is being treated with an ACE inhibitor. His medications include metformin, gliclazide and perindopril. He presents to the emergency department complaining of lightheadedness and dizziness, particularly when standing up. His blood pressure is 90/60 mmHg, and his heart rate is 70 bpm. His electrolytes show a potassium level of 6.2 mmol/L. Which of the following is the most likely cause of his hyperkalemia?

A. Adrenal insufficiency
B. Gliclazide
C. Perindopril
D. Dehydration
E. Metformin
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with right groin pain and a palpable mass. He reports constipation and mild nausea. Vitals are stable. The provided image was obtained. What is the MOST appropriate next step in management?

A. Manual reduction attempt
B. Stool softeners and observation
C. Broad-spectrum antibiotics
D. Surgical consultation for emergent repair
E. Increase oral fluid intake and monitor
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CT scan showing hemothorax caused by warfarin use
Image by Cevik Y CC BY 3.0 · Source

A 72-year-old male presents to the ED with sudden onset shortness of breath and right-sided chest pain. He has a history of atrial fibrillation and has been taking warfarin for the past 5 years. His INR is currently 6.0. A CT scan of the chest is performed (image attached). What is the MOST appropriate initial management step?

A. Administer intravenous vitamin K and prothrombin complex concentrate (PCC)
B. Administer intravenous tranexamic acid
C. Administer intravenous protamine sulfate
D. Perform a needle thoracostomy
E. Observe and monitor the patient's respiratory status
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Ovarian Cyst
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old woman presents with a 4-month history of increasing abdominal distension, bloating, and a sensation of early fullness after eating. She has also noticed a gradual increase in her waist circumference and reports feeling more fatigued than usual. Her medical history includes well-controlled type 2 diabetes mellitus and hypercholesterolaemia, managed with metformin and atorvastatin respectively. She is post-menopausal, having completed menopause 10 years ago. On physical examination, her vital signs are stable: blood pressure 128/78 mmHg, heart rate 68 bpm, respiratory rate 14/min, and temperature 36.6°C. Abdominal examination reveals moderate distension and a firm, irregular mass is palpable extending from the pelvis into the lower abdomen. Bowel sounds are present and normal. A recent transvaginal ultrasound was inconclusive due to the size of the mass, prompting a CT scan of the abdomen and pelvis, an axial image from which is shown. Given the clinical presentation and the findings on the image, what is the most appropriate immediate next step in the management of this patient?

A. Arrange for a fine needle aspiration biopsy of the mass under CT guidance.
B. Prescribe a course of broad-spectrum antibiotics for presumed pelvic inflammatory disease.
C. Schedule a follow-up CT scan in 3 months to monitor for changes in the mass size and appearance.
D. Referral to a gynaecological oncologist and measurement of serum CA-125.
E. Referral to a general surgeon for urgent exploratory laparotomy.
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 65-year-old asymptomatic woman undergoes a screening mammogram. The image shows the findings. Her previous mammograms have been unremarkable. What is the MOST appropriate next step in the management of this patient?

A. Stereotactic core biopsy
B. MRI of the breast
C. Excisional biopsy
D. Ultrasound of the breast
E. Reassurance and routine screening in 1 year
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old presents with acute cholangitis (fever, jaundice, RUQ pain). LFTs show obstructive pattern. ERCP is performed for biliary decompression and stone extraction. Following successful cannulation and cholangiography, the image is obtained. Based on the findings demonstrated in the image, what is the most appropriate immediate next step during this procedure?

A. Terminate the procedure and schedule surgery
B. Attempt stone extraction with a balloon catheter
C. Administer intravenous antibiotics and observe
D. Perform a sphincterotomy
E. Insert a biliary stent
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male undergoes a CT scan for investigation of chronic back pain. He is otherwise asymptomatic with stable vital signs. The image provided is an axial view from this scan. Based on this finding, what is the most appropriate next step in the patient's management according to current guidelines?

A. Schedule elective endovascular aneurysm repair (EVAR).
B. Arrange for urgent surgical consultation.
C. No further follow-up is required.
D. Repeat CT angiography in 6 months.
E. Arrange for surveillance ultrasound in 12 months.
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 72-year-old patient presents with a 4-month history of tenesmus and occasional bright red rectal bleeding. Colonoscopy was performed, and a representative image is shown. Biopsies confirm adenocarcinoma. Considering the likely stage suggested by the endoscopic appearance, which investigation is MOST crucial for pre-operative staging?

A. PET scan
B. Endorectal ultrasound
C. Repeat colonoscopy to assess proximal colon
D. CT scan of the chest, abdomen, and pelvis
E. Bone scan
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male with a history of hypertension and hyperlipidemia presents for a routine follow-up. He is asymptomatic. A contrast-enhanced CT abdomen, axial view shown, was performed as part of a screening protocol. What is the MOST appropriate next step?

A. Initiate beta-blocker therapy
B. Prescribe a statin for lipid management
C. Start aspirin for antiplatelet therapy
D. Repeat imaging in 6-12 months
E. Refer for immediate surgical repair
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 70-year-old male with known cirrhosis secondary to non-alcoholic fatty liver disease presents for routine surveillance. He has Child-Pugh class A cirrhosis and ECOG performance status 0. His recent surveillance ultrasound showed a new 3 cm lesion in segment VIII. Serum alpha-fetoprotein is elevated at 450 ng/mL. A contrast-enhanced ultrasound was performed, and representative images are shown. Considering the patient's history, clinical status, laboratory results, and the findings demonstrated in the contrast-enhanced ultrasound images, what is the MOST appropriate immediate next step in the management of this patient?

A. Referral to a multidisciplinary liver tumour board for treatment planning
B. Start systemic chemotherapy with Sorafenib
C. Repeat the contrast-enhanced ultrasound in 3 months
D. Initiate palliative care referral
E. Perform an urgent liver biopsy of the lesion
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An elderly man presents with a 6-month history of memory decline, recurrent falls, visual hallucinations, agitation, and confusion. His wife reports he talks to people who are not visible. Which of the following clinical features is most helpful in diagnosing his condition?

A. Nystagmus
B. Parkinsonian gait/tremor
C. Ataxia
D. Aphasia
E. Hemiparesis
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 68-year-old male with a history of chronic hepatitis C presents to the clinic complaining of right upper quadrant abdominal pain and unintentional weight loss of 10 kg over the past 6 months. His past medical history is significant for well-controlled hypertension and hyperlipidemia. Physical examination reveals mild hepatomegaly. Laboratory investigations show elevated alpha-fetoprotein (AFP) levels. A contrast-enhanced ultrasound of the liver is performed, and representative images are shown. Based on the imaging and clinical context, which of the following is the MOST appropriate next step in management?

A. Radiofrequency ablation of the lesion
B. Surveillance with serial AFP measurements and ultrasound every 3 months
C. Surgical resection of the lesion
D. Initiation of systemic chemotherapy with sorafenib
E. Referral for liver biopsy to confirm diagnosis and assess grade
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 68-year-old presents with a 3-day history of fever, jaundice, and severe RUQ pain radiating to the back. Vitals: T 38.5°C, BP 110/70, HR 95. LFTs show bilirubin 150, ALP 450, ALT 120. An ERCP is performed for stone extraction. The image is captured during the procedure after cannulation. Considering the findings demonstrated in the image, what is the most appropriate immediate next step in management during the current procedure?

A. Attempt balloon dilation of the distal duct without sphincterotomy
B. Place a biliary stent and schedule follow-up ERCP
C. Perform endoscopic sphincterotomy
D. Attempt stone fragmentation with lithotripsy before sphincterotomy
E. Abandon the procedure and refer for surgical exploration
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents to his GP with a 6-month history of intermittent postprandial fullness and mild dysphagia, particularly with solid foods. He reports occasional regurgitation but denies significant heartburn or chest pain. His vital signs are stable, and physical examination is unremarkable. Recent blood tests show mild iron deficiency anaemia. The provided image is from a CT scan of the chest and upper abdomen performed as part of his investigation. Considering the clinical presentation and the significant anatomical finding demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. Schedule regular clinical follow-up and repeat imaging in 12 months.
B. Arrange for upper gastrointestinal endoscopy with biopsies.
C. Referral for surgical assessment and repair.
D. Initiate high-dose proton pump inhibitor therapy and review in 3 months.
E. Advise dietary modification, elevation of the head of the bed, and weight loss.
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 65-year-old male with recently diagnosed gastric mixed adenoneuroendocrine carcinoma presents with unintentional weight loss. Endoscopy confirmed the diagnosis. Staging imaging is provided. His ECOG performance status is 1. Considering the extent of disease demonstrated, which of the following represents the most appropriate initial therapeutic approach?

A. Gastrectomy with D2 lymphadenectomy
B. Observation with regular imaging surveillance
C. Palliative radiotherapy to the gastric primary
D. Liver resection of dominant lesions
E. Systemic chemotherapy or targeted therapy
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A 70-year-old woman with a history of hypertension presents with fatigue, shortness of breath, and bilateral leg swelling. Echocardiography shows an ejection fraction of 30%. What is the most appropriate first-line treatment?

A. Calcium channel blocker
B. Nitrate therapy
C. ACE inhibitor and beta-blocker
D. Digoxin
E. Diuretic therapy alone
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old man presents to the emergency department with a 2-day history of worsening left lower quadrant abdominal pain, associated with subjective fever, chills, and nausea. He reports some recent constipation. His past medical history includes hypertension and hyperlipidaemia, both well-controlled on medication. On examination, his temperature is 38.5°C, pulse 95 bpm, BP 130/80 mmHg, respiratory rate 18/min, oxygen saturation 98% on room air. Abdominal examination reveals tenderness and guarding in the left iliac fossa, with mild rebound tenderness. Bowel sounds are reduced. Digital rectal examination is unremarkable. Blood tests show a white cell count of 15 x 10^9/L (neutrophils 85%), haemoglobin 145 g/L, platelets 250 x 10^9/L, C-reactive protein of 120 mg/L. Urea, electrolytes, and creatinine are within normal limits. Liver function tests are normal. A CT scan of the abdomen and pelvis is performed (image provided). Considering the clinical presentation and the specific findings demonstrated in the provided image, which of the following interventions is most likely to be required in addition to intravenous antibiotics and supportive care?

A. Administration of oral laxatives to relieve constipation
B. Urgent surgical resection of the affected bowel segment
C. Percutaneous drainage of a fluid collection
D. Placement of a nasogastric tube for bowel decompression
E. Endoscopic stenting of a colonic stricture
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X-ray of hiatal hernia
Image by Ahmed Farhat, Daryn Towle CC BY 4.0 · Source

A 68-year-old male with a history of reflux presents with epigastric pain and vomiting. An X-ray is performed (shown). What is the most likely complication?

A. Gastric volvulus
B. Pericarditis
C. Esophageal stricture
D. Aortic dissection
E. Pneumonia
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents with abdominal distension, vomiting, and inability to pass flatus for 48 hours. He has a history of prior bowel resection. Examination reveals a tympanitic abdomen and tenderness to palpation. His vitals are stable. An abdominal X-ray is performed, as shown. Considering the clinical context and the radiographic findings, what is the MOST likely underlying cause of this presentation?

A. Post-surgical adhesions
B. Inflammatory bowel disease stricture
C. Volvulus
D. Hernia
E. Malignancy
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 72-year-old woman presents with a 2-day history of worsening right upper quadrant pain radiating to her back, associated with nausea and a low-grade fever. On examination, she is jaundiced and has tenderness in the right upper quadrant. Laboratory tests show a total bilirubin of 75 µmol/L, ALP 350 U/L, ALT 200 U/L, and WCC 13.5 x 10^9/L. An urgent ERCP is performed, during which the image is captured. Following successful endoscopic clearance and clinical improvement, which of the following is the MOST appropriate long-term management strategy?

A. Long-term treatment with ursodeoxycholic acid
B. Repeat ERCP with cholangiogram in 3 months
C. Regular monitoring of liver function tests every 6 months
D. Strict adherence to a low-fat diet
E. Elective laparoscopic cholecystectomy
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male with a history of multiple abdominal surgeries presents to the emergency department complaining of abdominal pain, distension, and obstipation for the past 3 days. His vital signs are: HR 110 bpm, BP 110/70 mmHg, RR 22 breaths/min, SpO2 97% on room air, and temperature 37.8°C. Physical examination reveals a distended abdomen with high-pitched bowel sounds. An upright abdominal X-ray is performed, as shown. Given the clinical context and the radiographic findings, which demonstrate significant intraluminal gas accumulation proximal to the likely site of obstruction, what is the predominant source of this gas?

A. Diffusion from blood
B. Swallowed atmospheric air
C. Pancreatic enzyme activity
D. Biliary secretion
E. Bacterial fermentation
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Hepatic metastases from a gastric mixed adenoneuroendocrine carcinoma (MANEC).
Image by Hellerhoff CC BY-SA 3.0 · Source

A 65-year-old male presents with a 3-month history of unintentional weight loss and epigastric discomfort. Endoscopy revealed a gastric mass, and biopsy confirmed a mixed adenoneuroendocrine carcinoma. Staging imaging is shown. His ECOG performance status is 1. Considering the clinical presentation and the findings demonstrated in the provided images, what is the most appropriate initial management strategy for this patient?

A. Refer for surgical assessment for hepatic metastasectomy
B. Evaluate for potential liver transplantation
C. Plan for palliative external beam radiotherapy to the liver
D. Initiate systemic chemotherapy targeting the adenocarcinoma component
E. Commence treatment with a long-acting somatostatin analogue
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A 65-year-old patient with a history of DVT presents with sudden onset dyspnoea and pleuritic chest pain. Examination is unremarkable except for mild tachypnoea. Wells score is 4. Which initial investigation is most appropriate in the diagnostic pathway?

A. D-dimer
B. Lower limb ultrasound
C. V/Q scan
D. CT Pulmonary Angiogram (CTPA)
E. Chest X-ray
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents to the ED with left lower quadrant abdominal pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed. Based on the imaging, what is the MOST appropriate next step in management?

A. Flexible sigmoidoscopy to rule out malignancy
B. Stool culture to identify infectious etiology
C. Surgical resection of the affected bowel segment
D. IV antibiotics and bowel rest
E. High-fiber diet and increased fluid intake
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 65-year-old male with known cirrhosis secondary to chronic hepatitis B presents with increasing abdominal distension and fatigue. He has mild ascites. Liver function tests show bilirubin 35 umol/L, INR 1.3, albumin 30 g/L. AFP is 850 ng/mL. Imaging is performed as shown. Based on the imaging findings and clinical presentation, which of the following treatment modalities is MOST likely to be considered for this patient?

A. Initiation of systemic targeted therapy
B. Referral for liver transplantation assessment
C. Percutaneous radiofrequency ablation
D. Transarterial chemoembolisation
E. Surgical resection
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old man presents with a 4-month history of increasing constipation alternating with loose stools, occasional rectal bleeding, and fatigue. He denies significant weight loss. Physical examination is unremarkable. Full blood count shows a haemoglobin of 115 g/L with low ferritin. A colonoscopy was performed, and the image provided is a representative view. Biopsies were taken from the observed lesion. Considering the clinical presentation and the endoscopic finding, what is the most appropriate next investigation to determine the extent of disease and inform definitive management planning?

A. PET scan
B. CT scan of chest, abdomen, and pelvis
C. Bone scan
D. Endoscopic ultrasound
E. MRI of the pelvis
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

An 82-year-old woman with a history of paroxysmal atrial fibrillation and a recent hospitalisation for pneumonia was discharged 5 days ago on warfarin 5mg daily. She presents to the emergency department complaining of increasing pain and a rapidly evolving lesion on her right lower leg over the past 48 hours. She denies trauma. Her vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, Temp 36.8°C. Physical examination reveals the appearance shown in the image on her right anterior lower leg. Her INR today is 4.5. She has no known history of protein C or S deficiency. Considering the patient's history, current medication, laboratory result, and the clinical appearance depicted, which of the following represents the most appropriate immediate management strategy?

A. Administer subcutaneous low molecular weight heparin and continue warfarin.
B. Initiate broad-spectrum antibiotics and arrange for surgical debridement.
C. Reduce the dose of warfarin and monitor the lesion closely.
D. Administer fresh frozen plasma to correct the INR and continue warfarin at a lower dose.
E. Stop warfarin, administer intravenous Vitamin K, and initiate therapeutic dose unfractionated heparin.
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents with abdominal distension, vomiting, and inability to pass flatus for 48 hours. He has a history of prior bowel resection. Examination reveals a tympanitic abdomen and tenderness to palpation. His vitals are stable. An abdominal X-ray is performed, as shown. What is the MOST appropriate next step in the management of this patient?

A. Insert a nasogastric tube and administer intravenous fluids
B. Administer a Fleet enema
C. Order a CT scan of the abdomen and pelvis with intravenous contrast
D. Administer oral contrast and repeat abdominal X-ray in 6 hours
E. Perform a flexible sigmoidoscopy to rule out sigmoid volvulus
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

Mrs. Eleanor Vance, a 62-year-old retired teacher, presents for her routine biennial screening mammogram through the BreastScreen Australia program. She has no personal history of breast disease, and her family history is negative for breast or ovarian cancer in first-degree relatives. She is otherwise healthy, with a history of diet-controlled type 2 diabetes and osteoarthritis managed with paracetamol. She denies any breast pain, lumps, nipple discharge, or skin changes. Her last mammogram two years ago was reported as normal (BIRADS 1). Physical examination of both breasts and axillae is unremarkable. The current screening mammogram is performed. The image provided is a magnified view from the craniocaudal projection of the left breast, specifically highlighting an area that has been flagged for further assessment by the reporting radiologist due to a change from the previous study. Assuming that subsequent investigation of the area highlighted in the image confirms a diagnosis of ductal carcinoma in situ (DCIS) and the patient undergoes breast-conserving surgery, which of the following factors is most important in determining the need for adjuvant radiotherapy?

A. Patient's body mass index (BMI)
B. Margin status of the surgical excision specimen
C. Oestrogen receptor status of the DCIS cells
D. Ki-67 proliferation index of the DCIS cells
E. Presence of metastatic disease on staging scans
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An 82-year-old man with a history of COPD and mild dementia is brought to the emergency department by his family due to increased confusion over 24 hours. He has had a low-grade fever (37.8°C) and a mild cough for 3 days. On examination, he is drowsy but rousable. His oxygen saturation is 90% on room air. Chest auscultation reveals decreased breath sounds at the bases. A chest X-ray shows bilateral lower lobe infiltrates. His CURB-65 score is 3. Considering the patient's presentation and CURB-65 score, what is the most appropriate initial management plan?

A. Admission to hospital for observation and oral antibiotics.
B. Discharge home with supportive care and review in 24 hours.
C. Admission to ICU for mechanical ventilation and broad-spectrum antibiotics.
D. Outpatient management with oral antibiotics and close follow-up.
E. Admission to hospital with intravenous antibiotics.
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Contrast-enhanced ultrasound of encephaloid hepatocellular carcinoma
Image by R. Badea, Simona Ioanitescu CC BY 3.0 · Source

A 70-year-old male with known cirrhosis secondary to NAFLD is undergoing routine surveillance. A new 3 cm lesion was identified in segment VIII on ultrasound, with AFP 45. Contrast-enhanced ultrasound was performed, with representative images shown. Based on the clinical context and the findings demonstrated, what is the most appropriate immediate next step in this patient's management?

A. Schedule repeat contrast-enhanced ultrasound in 3 months
B. Schedule for surgical resection
C. Referral to a multidisciplinary liver tumour board
D. Perform a percutaneous liver biopsy of the lesion
E. Initiate systemic therapy with sorafenib
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