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Practice targeted AMC-style multiple-choice questions on general practice.

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A 32-year-old male presents to his GP complaining of a new, intensely itchy rash on his wrists and ankles. On examination, there are multiple small, flat-topped, polygonal, violaceous papules. Some of the papules have fine white lines on their surface. What is the most likely diagnosis?

A. Lichen planus
B. Psoriasis
C. Tinea corporis
D. Contact dermatitis
E. Atopic dermatitis
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A 55-year-old man, non-smoker, presents for a health check. BP 135/85 mmHg, total cholesterol 5.5 mmol/L, HDL 1.2 mmol/L. No personal history of CVD or diabetes. Family history of premature CVD in father. BMI 28. Based on Australian guidelines, what is the most appropriate initial management step?

A. Order a fasting glucose and HbA1c.
B. Start perindopril 5mg daily.
C. Start atorvastatin 20mg daily.
D. Calculate absolute cardiovascular risk and discuss lifestyle modification.
E. Advise weight loss and recheck BP in 6 months.
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A GP working in a hospital is observed getting into arguments with colleagues. Later, a colleague finds her disoriented and walking in the hallway. What is the most appropriate initial step?

A. Assume it is a personal matter and take no immediate action.
B. Advise the GP to go home and rest.
C. Talk to the GP privately to understand the issue.
D. Document the observations in the GP's personnel file.
E. Notify a superior or relevant authority (e.g., medical supervisor, head of department).
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A 32-year-old woman presents to the clinic with a 2-week history of a persistent cough and shortness of breath. She has no significant past medical history and is a non-smoker. On examination, she has bilateral wheezing and reduced breath sounds. A chest X-ray shows hyperinflation of the lungs. What is the most likely diagnosis?

A. Chronic obstructive pulmonary disease (COPD)
B. Asthma
C. Heart failure
D. Pneumonia
E. Pulmonary embolism
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A 62-year-old man presents with a 4-month history of increasing fatigue, unintentional weight loss of 7 kg, and intermittent upper abdominal discomfort. He reports no change in bowel habits, dysphagia, or vomiting. His past medical history includes hypertension and osteoarthritis. He is a non-smoker and drinks alcohol occasionally. On examination, he is pale. His vital signs are stable. Abdominal examination reveals mild epigastric tenderness but no masses or organomegaly. There is no peripheral lymphadenopathy. Initial blood tests show haemoglobin 92 g/L (reference range 130-170), MCV 74 fL (80-95), ferritin 12 mcg/L (30-300), and CRP 18 mg/L (<5). Liver function tests and renal function tests are within normal limits. Which of the following is the most appropriate initial investigation?

A. Abdominal and pelvic CT scan
B. Faecal occult blood testing
C. Gastroscopy and colonoscopy
D. Upper gastrointestinal barium study
E. Bone marrow biopsy
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 48-year-old man presents to his GP reporting an intermittent swelling in his right groin over the past six months. He notes it is more prominent when he is upright or coughing and disappears when he lies down. He experiences occasional mild discomfort but denies any acute pain, nausea, or vomiting. His past medical history is unremarkable, and vital signs are stable. Physical examination reveals the finding shown in the image. Considering the patient's history and the physical examination finding depicted, what is the most appropriate recommendation regarding definitive management for this patient?

A. Prescription of a truss for support
B. Watchful waiting with regular review
C. Elective surgical repair
D. Referral for ultrasound imaging
E. Urgent surgical exploration
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman presents for routine mammography. She has no palpable lumps or skin changes. Her previous mammogram two years ago was normal. The current mammogram is shown. What is the MOST appropriate next step in management?

A. Excisional biopsy
B. Ultrasound of the breast
C. Reassurance and routine screening in 2 years
D. Stereotactic core biopsy
E. MRI of the breast
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old man presents to his general practitioner expressing concern about the appearance of his chest, which he feels has become more prominent over the past 18 months. He denies any pain, tenderness, or nipple discharge. His medical history includes well-controlled hypertension managed with perindopril and occasional use of ibuprofen for mild osteoarthritis. He reports no significant changes in weight, appetite, or energy levels. He is a non-smoker and drinks alcohol socially, approximately 5 standard drinks per week. He works as an accountant and reports no exposure to unusual chemicals or substances. On physical examination, his vital signs are within normal limits. Abdominal examination reveals no hepatosplenomegaly. Testicular examination is normal in size and consistency, with no palpable masses. The image provided shows the appearance of his chest. Considering the patient's presentation and the visual finding, what is the most appropriate initial investigation to pursue?

A. Genetic testing for Klinefelter syndrome.
B. Serum levels of testosterone, luteinising hormone (LH), follicle-stimulating hormone (FSH), oestradiol, and prolactin.
C. Liver function tests and renal function tests.
D. Mammography of the chest to assess for underlying malignancy.
E. Referral for psychological assessment and counselling regarding body image concerns.
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 30-year-old immigrant presents with chronic cough and night sweats. Sputum is negative for AFB. What is the MOST appropriate next step in management?

A. Prescribe antitussives
B. Repeat sputum AFB
C. Start empiric antibiotics
D. Bronchoscopy with biopsy
E. Initiate isoniazid prophylaxis
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents with left lower quadrant pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed, the axial view is shown. What is the most appropriate next step in management?

A. Order a barium enema to assess for fistula
B. Prescribe oral antibiotics and a high-fiber diet
C. Perform a colonoscopy to rule out malignancy
D. Schedule elective sigmoid colectomy
E. Initiate intravenous antibiotics and bowel rest
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A 32-year-old woman presents to her GP complaining of a new, intensely itchy rash on her elbows, knees, and scalp. On examination, the GP notes symmetrical, erythematous papules and plaques with overlying silvery scales. The patient reports a family history of similar skin conditions. What is the most likely diagnosis?

A. Contact Dermatitis
B. Tinea Corporis
C. Pityriasis Rosea
D. Eczema (Atopic Dermatitis)
E. Psoriasis
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman presents for routine screening mammography. She has no palpable lumps or skin changes. Her mother was diagnosed with breast cancer at age 68. The provided image is from her mammogram. What is the MOST appropriate next step in management?

A. MRI of the breast
B. Ultrasound of the breast
C. Reassurance and routine screening in one year
D. Stereotactic core biopsy
E. Excisional biopsy
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A 45-year-old woman presents to the clinic with a 2-week history of a painful, swollen right calf. She recently returned from a long-haul flight from Europe. On examination, her right calf is warm, erythematous, and tender to touch. A D-dimer test is positive. What is the most appropriate next step in management?

A. Order a CT pulmonary angiogram
B. Advise bed rest and elevation of the leg
C. Start anticoagulation therapy immediately
D. Perform a Doppler ultrasound of the right leg
E. Prescribe compression stockings
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A 42-year-old woman, nulliparous, presents to her general practitioner with a palpable lump in her left breast, noticed two weeks ago. She reports some mild, intermittent tenderness associated with the lump, which she initially attributed to her menstrual cycle, but it has persisted. She has no significant family history of breast cancer. On examination, there is a 1.5 cm, firm, mobile lump in the upper outer quadrant. No skin changes or nipple discharge are noted. Axillary nodes are not palpable. She is otherwise well. Which of the following represents the most appropriate initial management step?

A. Reassurance and review in 3 months.
B. MRI of the breast.
C. Fine needle aspiration cytology of the lump.
D. Urgent mammography and ultrasound.
E. Referral to a specialist breast clinic for triple assessment.
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A 62-year-old Aboriginal and Torres Strait Islander man presents for a routine check-up. He has a history of smoking, obesity, and type 2 diabetes, managed with metformin. His blood pressure is 150/90 mmHg. Which of the following is the MOST significant modifiable risk factor for cardiovascular disease in this patient?

A. Type 2 diabetes
B. Smoking
C. Obesity
D. Indigenous status
E. Hypertension
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the ED with severe groin pain and a palpable mass. He reports constipation and inability to pass flatus for 24 hours. Examination reveals tenderness and erythema. A CT scan is performed. What is the MOST appropriate next step in management?

A. Stool softeners and observation
B. Surgical consultation for emergent repair
C. High-fibre diet and increased fluid intake
D. Antibiotics and close monitoring
E. Manual reduction with sedation
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 32-year-old male, recent immigrant from a high-TB prevalence country, presents with a persistent cough and night sweats for the past two months. He denies fever or weight loss. Physical examination is unremarkable except for mild, diffuse rhonchi on auscultation. Sputum cultures are pending. A PET-CT scan of the chest was performed, the axial view is shown. Given the clinical context and imaging findings, what is the MOST appropriate next step in management?

A. Prescribe a course of broad-spectrum antibiotics for presumed bacterial pneumonia
B. Initiate a four-drug anti-tuberculosis regimen
C. Repeat the PET-CT scan in three months to assess for interval growth
D. Start a course of oral corticosteroids to reduce inflammation
E. Order a bronchoscopy with transbronchial biopsy
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A 65-year-old woman presents to her general practitioner with fatigue and pallor. She has a history of rheumatoid arthritis, for which she takes methotrexate and folic acid. She denies any gastrointestinal symptoms or recent changes in her diet. On examination, she appears pale, and her conjunctivae are pale as well. Her blood pressure is 120/75 mmHg, heart rate is 88 bpm, and respiratory rate is 16 breaths per minute. Laboratory investigations reveal hemoglobin of 9.0 g/dL, mean corpuscular volume (MCV) of 105 fL, and normal white blood cell and platelet counts. Which of the following is the most likely cause of her anemia?

A. Iron deficiency anemia
B. Anemia of chronic disease
C. Hemolytic anemia
D. Methotrexate-induced macrocytic anemia
E. Vitamin B12 deficiency
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 55-year-old man presents to his GP with a lesion on his nose that he first noticed about 6 months ago. It has gradually increased in size but is not painful or itchy. He has no significant past medical history and takes no regular medications. On examination, vital signs are stable. The image shows the lesion. Based on the appearance of this lesion, what is the most appropriate next step in management?

A. Advise observation and review in 6 months.
B. Perform an excisional biopsy for histological examination.
C. Refer urgently to a dermatologist for Mohs surgery.
D. Prescribe a course of topical antibiotic cream.
E. Arrange for cryotherapy in the clinic.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents with LLQ pain and fever. The provided image was obtained. What is the most appropriate initial management?

A. Surgical consultation for possible resection
B. Oral antibiotics and outpatient follow-up
C. Colonoscopy to rule out malignancy
D. Stool culture to rule out infectious colitis
E. IV antibiotics and admission for observation
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A 40-year-old Aboriginal man presents for a health check. He has a strong family history of diabetes and cardiovascular disease. What is the most appropriate initial screening test to assess his risk?

A. Liver function tests
B. Urine analysis
C. Fasting blood glucose and lipid profile
D. Full blood count
E. ECG
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents with a painful, irreducible right groin mass. He reports vomiting and abdominal distension. His vitals are: HR 110, BP 100/60, RR 22, SpO2 96% RA. The provided image was obtained. What is the next step?

A. Attempt manual reduction with sedation
B. Surgical consultation for emergent repair
C. Order a repeat CT scan with contrast in 6 hours
D. Start a clear liquid diet
E. Administer intravenous antibiotics
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department complaining of abdominal pain, distension, and obstipation for the past 3 days. He reports a history of multiple abdominal surgeries for adhesions. His vital signs are: HR 110 bpm, BP 110/70 mmHg, RR 22 breaths/min, SpO2 97% on room air, and temperature 37.8°C. Physical examination reveals a distended abdomen with high-pitched bowel sounds. An upright abdominal X-ray is performed, as shown. Given the clinical context and the findings on the imaging, what is the MOST appropriate next step in management?

A. Insert a nasogastric tube and initiate intravenous fluid resuscitation
B. Prescribe oral laxatives and encourage increased fluid intake
C. Administer intravenous antibiotics and schedule an urgent CT scan with oral contrast
D. Order a barium enema to assess for colonic obstruction
E. Perform a flexible sigmoidoscopy to rule out sigmoid volvulus
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A 60-year-old non-smoker has a calculated 5-year cardiovascular disease risk of 12%. Based on current Australian guidelines, what is the most appropriate initial management focus?

A. Annual risk reassessment without intervention
B. Lifestyle modification and shared decision-making regarding pharmacotherapy
C. Immediate initiation of high-intensity statin therapy
D. Referral for specialist cardiology review
E. Low-dose aspirin therapy for primary prevention
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A 25-year-old woman presents to the clinic with a 3-day history of dysuria, increased urinary frequency, and urgency. She denies fever, flank pain, or vaginal discharge. She is sexually active and uses oral contraceptives. On examination, she is afebrile and her vital signs are stable. Urinalysis shows pyuria and bacteriuria. What is the most appropriate treatment?

A. Trimethoprim-sulfamethoxazole
B. Ciprofloxacin
C. Ceftriaxone
D. Amoxicillin
E. Nitrofurantoin
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 62-year-old man presents to his GP with a history of a bulge in his right groin that has been present for approximately 18 months. He reports it is more prominent with straining or standing and disappears completely when he lies down. He denies any associated pain, nausea, vomiting, or change in bowel habits. He has no significant past medical history. His physical examination reveals the finding depicted in the image. Vital signs are within normal limits. Based on this clinical picture, which of the following represents the most appropriate definitive management strategy for this patient?

A. Observation with regular follow-up.
B. Urgent surgical exploration.
C. Further imaging to confirm the diagnosis.
D. Elective surgical repair.
E. Non-surgical management with a supportive device.
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A 52-year-old woman presents to her GP with a palpable lump in her right breast. She reports no pain, nipple discharge, or skin changes. She has no family history of breast cancer. On examination, the lump is firm, non-tender, and mobile. There is no axillary lymphadenopathy. What is the most appropriate initial investigation?

A. Breast ultrasound
B. Mammography
C. Fine-needle aspiration (FNA)
D. MRI of the breast
E. Core biopsy
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A patient on warfarin presents with leg pain. INR is 3.5. Given the image, what is the MOST appropriate next step?

A. Stop warfarin and administer vitamin K
B. Elevate the leg and apply warm compresses
C. Continue warfarin at the same dose
D. Apply topical corticosteroids
E. Start heparin and continue warfarin
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male with a history of hypertension and hyperlipidemia presents for a routine follow-up. He is asymptomatic. A contrast-enhanced CT abdomen, axial view shown, was performed as part of a screening protocol. What is the MOST appropriate next step?

A. Initiate beta-blocker therapy
B. Prescribe a statin for lipid management
C. Start aspirin for antiplatelet therapy
D. Repeat imaging in 6-12 months
E. Refer for immediate surgical repair
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the ED with severe groin pain and a palpable mass. He reports a history of a reducible bulge in the same area, but today it is firm and tender. He denies fever, nausea, or vomiting. Examination reveals stable vital signs. Review the provided image. What is the MOST appropriate next step in management?

A. Pain management and discharge with surgical follow-up
B. Referral for elective surgical repair
C. Broad-spectrum antibiotics and observation
D. Trial of manual reduction with sedation
E. Surgical consultation for emergent repair
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A 52-year-old woman presents to her general practitioner with fatigue, increased thirst, and frequent urination over the past three months. She has a history of hypertension and hyperlipidemia, for which she takes lisinopril and atorvastatin. Her BMI is 32 kg/m². On examination, her blood pressure is 140/85 mmHg, and her heart rate is 78 bpm. Laboratory tests reveal a fasting plasma glucose of 8.5 mmol/L and an HbA1c of 7.2%. She is diagnosed with type 2 diabetes mellitus. Which of the following is the most appropriate initial management step for this patient according to Australian guidelines?

A. Lifestyle modification including diet and exercise
B. Commencement of insulin therapy
C. Initiation of metformin therapy
D. Referral to an endocrinologist
E. Addition of a sulfonylurea
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A 65-year-old man with a history of COPD presents with fever, productive cough, and shortness of breath for 3 days. On examination, he has crackles in the right lower lung field. A chest X-ray shows a right lower lobe consolidation. What is the most likely diagnosis?

A. Tuberculosis
B. Lung cancer
C. Heart failure
D. Pulmonary embolism
E. Community-acquired pneumonia
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old man presents with concerns about breast enlargement over the past year. He denies pain or nipple discharge. He takes medication for hypertension. Examination reveals the findings in the image. Which of the following is the MOST appropriate initial investigation?

A. Review medication list and consider alternative antihypertensive
B. Reassurance and observation
C. Fine needle aspiration of breast tissue
D. Serum prolactin and testosterone levels
E. Mammogram and ultrasound of the breasts
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An Aboriginal woman, 48 years old, attends your general practice for a routine health check. She has a history of gestational diabetes and lives in a rural community. When discussing preventative health screening, which of the following is the MOST culturally appropriate and evidence-based approach?

A. Refer her to a specialist diabetes clinic in a major city for comprehensive assessment and management, ensuring she understands the importance of specialist care.
B. Recommend genetic testing for diabetes risk, as Aboriginal Australians have a higher prevalence of certain genetic predispositions.
C. Offer a comprehensive assessment including HbA1c, urine albumin creatinine ratio, blood pressure, BMI, smoking and alcohol use, and discuss cardiovascular risk, while acknowledging the impact of social determinants of health and incorporating her preferences for health management.
D. Focus primarily on diabetes screening with HbA1c testing, as she has a history of gestational diabetes, and provide written information about diabetes management.
E. Advise her to follow a standard Western diet and exercise plan to manage her diabetes risk, as these are proven effective strategies.
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old man presents with bilateral breast enlargement, as shown. He denies pain or nipple discharge. What is the MOST likely underlying cause?

A. Liver cirrhosis
B. Medication side effect
C. Hyperthyroidism
D. Klinefelter syndrome
E. Testicular cancer
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 62-year-old male presents with acute onset of LLQ pain, fever, and vomiting. His WBC count is elevated. A CT scan of the abdomen and pelvis is performed. Based on the image, what is the most appropriate next step in management?

A. Flexible sigmoidoscopy
B. IV antibiotics and bowel rest
C. Stool softeners
D. Surgical resection
E. High-fiber diet
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A 52-year-old woman presents to her general practitioner with concerns about irregular menstrual bleeding over the past six months. She has a history of obesity, with a BMI of 32 kg/m², and was recently diagnosed with type 2 diabetes mellitus. She reports that her periods have been irregular for the past few years, often skipping months. She is not currently on any hormone replacement therapy. On examination, she has no signs of hirsutism or virilization. Her blood pressure is 140/85 mmHg, and her fasting blood glucose level is 8.5 mmol/L. Which of the following groups of women is most at risk for developing endometrial hyperplasia?

A. Women with a history of smoking and low BMI
B. Women with obesity and chronic anovulation
C. Women on combined oral contraceptive pills
D. Women who have undergone hysterectomy
E. Women with a history of regular menstrual cycles
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 58-year-old male presents to your GP clinic complaining of a dragging sensation in his groin, noticeable especially when standing for long periods. On examination, you observe the finding in the image. He denies any pain. What is the MOST appropriate initial management?

A. Reassurance and watchful waiting
B. Trial of analgesia with NSAIDs
C. Referral for urgent ultrasound
D. Referral to general surgery for elective repair
E. Prescription of a scrotal support
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A 62-year-old woman presents to her general practitioner with a 3-month history of progressive shortness of breath, fatigue, and a persistent dry cough. She has a history of rheumatoid arthritis, for which she takes methotrexate and low-dose prednisone. She denies fever, weight loss, or night sweats. On examination, she has clubbing of the fingers and fine inspiratory crackles at the lung bases. Her oxygen saturation is 92% on room air. A chest X-ray shows reticular opacities predominantly in the lower lung zones. Pulmonary function tests reveal a restrictive pattern with reduced diffusion capacity for carbon monoxide (DLCO). Which of the following is the most appropriate next step in the management of this patient?

A. Initiate supplemental oxygen therapy
B. Start azathioprine
C. Refer for lung biopsy
D. Increase the dose of prednisone
E. High-resolution computed tomography (HRCT) of the chest
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old male presents with bilateral breast enlargement for 6 months. He denies pain, discharge, or skin changes. He reports taking saw palmetto for BPH. Examination reveals the findings in the image. What is the MOST likely cause?

A. Hyperthyroidism
B. Testicular cancer
C. Cirrhosis
D. Idiopathic
E. Medication side effect
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

An 68-year-old man attends his GP for a routine check-up. He has a history of well-controlled type 2 diabetes, hypertension, and smoked for 30 years, quitting 5 years ago. He denies any abdominal pain, back pain, or pulsatile sensation. Physical examination is unremarkable. As part of a cardiovascular risk assessment, an abdominal ultrasound is initially performed, which is inconclusive due to bowel gas. A follow-up contrast-enhanced CT scan is arranged. Considering the findings demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. No further action required, reassure the patient
B. Immediate admission for urgent surgical assessment
C. Referral for elective surgical repair
D. Repeat CT scan in 3 months
E. Six-monthly abdominal ultrasound surveillance
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A 35-year-old Aboriginal woman presents for a routine health check. She reports feeling tired lately and sometimes short of breath on exertion. She has a history of type 2 diabetes diagnosed 5 years ago, managed with metformin 500mg twice daily, and untreated hypertension. On examination, her blood pressure is 145/90 mmHg. Urinalysis shows 2+ protein. Blood tests reveal creatinine 180 µmol/L, eGFR 35 mL/min/1.73m², HbA1c 8.5%, potassium 4.2 mmol/L. Given these findings, which of the following is the most appropriate initial management step?

A. Increase the dose of metformin.
B. Prescribe a loop diuretic for fluid overload.
C. Advise dietary protein restriction only.
D. Initiate an ACE inhibitor or ARB and optimise blood pressure control.
E. Refer immediately for renal biopsy.
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 45-year-old male, who recently immigrated from India, presents to his primary care physician with a two-month history of progressive fatigue, unintentional weight loss of 7 kg, and intermittent night sweats. He denies any cough, chest pain, or shortness of breath. He has no significant past medical history and is not currently taking any medications. Physical examination reveals normal vital signs, including a temperature of 37.1°C, and clear breath sounds bilaterally. However, mild cervical lymphadenopathy is noted. Initial laboratory investigations, including a complete blood count and comprehensive metabolic panel, are unremarkable. A chest X-ray reveals a solitary pulmonary nodule in the right upper lobe, which prompts a PET-CT scan for further evaluation. An axial slice from the PET-CT is shown. Given the patient's clinical presentation, immigration history, and the PET-CT findings, which of the following is the MOST appropriate next step in establishing a definitive diagnosis?

A. Bronchoscopy with transbronchial needle aspiration of the lesion
B. Administer a purified protein derivative (PPD) skin test
C. Order a CT-guided percutaneous needle biopsy of the lung nodule
D. Repeat PET-CT scan in three months to assess for interval growth
E. Initiate empiric antibiotic therapy with a broad-spectrum antibiotic
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman presents for routine mammography. The image is shown. What is the MOST appropriate next step?

A. Reassurance and routine screening
B. Stereotactic core biopsy
C. Ultrasound of the breast
D. MRI of the breast
E. Excisional biopsy
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A 55-year-old man presents to the clinic with a 3-month history of worsening cough, weight loss, and night sweats. He has a 30-pack-year smoking history and worked in construction for 20 years. On examination, he has clubbing of the fingers and decreased breath sounds in the right lower lung field. A chest X-ray shows a right lower lobe mass. What is the most appropriate next step in the management of this patient?

A. Order sputum cytology
B. Perform a PET scan
C. Refer for bronchoscopy
D. Obtain a CT scan of the chest
E. Start empirical antibiotics
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old male presents to his GP with bilateral breast tenderness and swelling over six months. He denies nipple discharge or other systemic symptoms. Past medical history is unremarkable, and he takes no regular medications. Physical examination reveals the findings shown in the image. Vital signs are normal. Initial investigations including liver function tests, renal function tests, thyroid function tests, LH, FSH, prolactin, and testosterone are all within normal limits. Considering the clinical presentation, image findings, and normal initial investigations, which of the following is the most appropriate next step in the evaluation of this patient?

A. CT scan of the chest, abdomen, and pelvis
B. Referral for genetic testing for Klinefelter syndrome
C. Breast ultrasound and mammography
D. Initiate a trial of tamoxifen
E. Scrotal ultrasound
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male with a history of smoking presents for a routine check-up. The image is taken. What is the recommended surveillance interval?

A. No further imaging required
B. Initiate statin therapy and monitor annually
C. Repeat imaging in 6-12 months
D. Immediate surgical consultation
E. Repeat imaging in 3 years
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash that started a few weeks ago. She reports that it began on her wrists and ankles and has now spread to her elbows and knees. She denies any new medications, travel, or changes in personal care products. On examination, you observe symmetrical, intensely pruritic, violaceous, flat-topped papules and plaques on her wrists, ankles, and shins. Some of the lesions show fine, white lines on the surface. There are also a few small, similar lesions on her buccal mucosa. Which of the following is the most appropriate initial management?

A. Systemic corticosteroids and antifungal cream
B. Topical corticosteroids and antihistamines
C. Oral antibiotics and topical emollients
D. Referral to a rheumatologist for autoimmune workup
E. Cryotherapy to the affected areas
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old male presents with acute LLQ pain. The provided image was obtained. What dietary advice is most appropriate upon resolution of acute symptoms?

A. Low-residue diet
B. Gluten-free diet
C. Lactose-free diet
D. Elemental diet
E. High-fibre diet
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A 55-year-old lady presents with a painless, white, lacy pattern on her buccal mucosa that has been present for several weeks. She feels well and has no significant medical history. What is the likely diagnosis?

A. Oral lichen planus
B. Leukoplakia
C. Squamous cell carcinoma
D. Oral candidiasis
E. Erythroplakia
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