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Practice targeted AMC-style multiple-choice questions on general practice.

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Umbilical hernia
Image by Ibrahim Husain Meraj CC BY-SA 4.0 · Source

A 2-year-old child is brought to the GP by their parents who are concerned about the appearance of their child's abdomen. The child is asymptomatic, feeding well, and has no history of vomiting or pain. On examination, vital signs are normal. Considering the clinical presentation and the finding shown in the image, what is the most appropriate initial management?

A. Arrange an urgent abdominal ultrasound.
B. Urgent surgical referral for repair.
C. Application of an abdominal binder or tape.
D. Prescription of paracetamol and review in 3 months.
E. Observation and reassurance, advising review if symptomatic or persistent beyond age 4-5 years.
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Umbilical hernia
Image by Ibrahim Husain Meraj CC BY-SA 4.0 · Source

A 3-year-old child is brought to the GP by their parents who are worried about the appearance of their child's abdomen, as shown in the image. The child is otherwise well, active, and has no pain, vomiting, or changes in bowel habits. On examination, the finding is soft and easily reducible. Vital signs are normal. Based on this presentation and the image, what is the most appropriate initial management?

A. Application of a binder or tape over the area.
B. Advise strict bed rest to prevent worsening.
C. Request an abdominal ultrasound to assess contents.
D. Reassurance and observation for spontaneous closure.
E. Urgent surgical referral for repair.
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 58-year-old male presents to your GP clinic complaining of a dragging sensation in his right groin, particularly when standing for long periods. He denies any pain, nausea, or vomiting. On examination, you note the finding in the image. Palpation reveals a soft, reducible mass. What is the MOST appropriate next step in management?

A. Referral to a general surgeon for elective repair
B. Referral to physiotherapy for core strengthening exercises
C. Urgent referral to the emergency department
D. Prescription of a truss for symptomatic relief
E. Reassurance and watchful waiting
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 58-year-old woman attends a routine mammography screening. She reports no palpable lumps, pain, or nipple discharge. Her family history is unremarkable. The image shows the findings of the current mammogram. What is the MOST appropriate next step in the management of this patient?

A. Reassurance and routine screening in 1 year
B. Excisional biopsy
C. MRI of the breast
D. Ultrasound of the breast
E. Stereotactic core biopsy
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A 30-year-old woman presents to her GP with a 2-week history of a persistent cough, night sweats, and unintentional weight loss. She has recently returned from a trip to Southeast Asia. On examination, she appears thin and has crackles in the upper zones of her lungs. A chest X-ray shows cavitary lesions in the right upper lobe. What is the most likely diagnosis?

A. Chronic obstructive pulmonary disease (COPD)
B. Pulmonary tuberculosis
C. Pneumonia
D. Sarcoidosis
E. Lung cancer
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old man presents to his general practitioner expressing concern about the appearance of his chest, which he feels has become more prominent over the past 18 months. He denies any pain, tenderness, or nipple discharge. His medical history includes well-controlled hypertension managed with perindopril and occasional use of ibuprofen for mild osteoarthritis. He reports no significant changes in weight, appetite, or energy levels. He is a non-smoker and drinks alcohol socially, approximately 5 standard drinks per week. He works as an accountant and reports no exposure to unusual chemicals or substances. On physical examination, his vital signs are within normal limits. Abdominal examination reveals no hepatosplenomegaly. Testicular examination is normal in size and consistency, with no palpable masses. The image provided shows the appearance of his chest. Considering the patient's presentation and the visual finding, what is the most appropriate initial investigation to pursue?

A. Genetic testing for Klinefelter syndrome.
B. Serum levels of testosterone, luteinising hormone (LH), follicle-stimulating hormone (FSH), oestradiol, and prolactin.
C. Liver function tests and renal function tests.
D. Mammography of the chest to assess for underlying malignancy.
E. Referral for psychological assessment and counselling regarding body image concerns.
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 30-year-old immigrant presents with chronic cough and night sweats. Sputum is negative for AFB. What is the MOST appropriate next step in management?

A. Prescribe antitussives
B. Repeat sputum AFB
C. Start empiric antibiotics
D. Bronchoscopy with biopsy
E. Initiate isoniazid prophylaxis
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 45-year-old woman presents with RUQ pain, fever, and nausea. The image shows the likely cause. What is the MOST appropriate next step in management?

A. Observation and oral analgesics
B. IV antibiotics and analgesia
C. HIDA scan
D. ERCP with sphincterotomy
E. Laparoscopic cholecystectomy
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman presents for routine screening mammography. She has no palpable lumps or skin changes. Her mother was diagnosed with breast cancer at age 68. The provided image is from her mammogram. What is the MOST appropriate next step in management?

A. MRI of the breast
B. Ultrasound of the breast
C. Reassurance and routine screening in one year
D. Stereotactic core biopsy
E. Excisional biopsy
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A 62-year-old man presents to his general practitioner with a 6-month history of a bulge in his groin that appears when he strains or coughs. He reports mild discomfort but no severe pain. On examination, the GP identifies a soft, reducible mass in the right groin area that appears to emerge through the superficial inguinal ring when the patient coughs. The mass reduces spontaneously when the patient lies down. Which of the following is the most appropriate next step in management, according to Australian guidelines?

A. Urgent referral to the emergency department for strangulation risk
B. Referral to a general surgeon for elective repair
C. Referral for an abdominal CT scan to rule out other pathology
D. Reassurance and watchful waiting with lifestyle advice
E. Prescription of a truss to support the hernia
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A 42-year-old woman, nulliparous, presents to her general practitioner with a palpable lump in her left breast, noticed two weeks ago. She reports some mild, intermittent tenderness associated with the lump, which she initially attributed to her menstrual cycle, but it has persisted. She has no significant family history of breast cancer. On examination, there is a 1.5 cm, firm, mobile lump in the upper outer quadrant. No skin changes or nipple discharge are noted. Axillary nodes are not palpable. She is otherwise well. Which of the following represents the most appropriate initial management step?

A. Reassurance and review in 3 months.
B. MRI of the breast.
C. Fine needle aspiration cytology of the lump.
D. Urgent mammography and ultrasound.
E. Referral to a specialist breast clinic for triple assessment.
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for routine follow-up. He is asymptomatic. Review the image. What is the most appropriate next step in management?

A. Commence dual antiplatelet therapy
B. Repeat imaging in 6-12 months
C. Prescribe a statin
D. Initiate beta-blocker therapy
E. Schedule elective surgical repair
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for a routine health check. She reports intermittent episodes of colicky abdominal pain over the past year, which have since resolved. An abdominal ultrasound was performed, the image of which is shown. Liver function tests are within normal limits. Which of the following is the MOST appropriate next step in management?

A. Repeat ultrasound in 6 months
B. Prescribe ursodeoxycholic acid
C. Referral for elective cholecystectomy
D. Order a HIDA scan
E. Initiate a low-fat diet and monitor symptoms
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 32-year-old male, recent immigrant from a high-TB prevalence country, presents with a persistent cough and night sweats for the past two months. He denies fever or weight loss. Physical examination is unremarkable except for mild, diffuse rhonchi on auscultation. Sputum cultures are pending. A PET-CT scan of the chest was performed, the axial view is shown. Given the clinical context and imaging findings, what is the MOST appropriate next step in management?

A. Prescribe a course of broad-spectrum antibiotics for presumed bacterial pneumonia
B. Initiate a four-drug anti-tuberculosis regimen
C. Repeat the PET-CT scan in three months to assess for interval growth
D. Start a course of oral corticosteroids to reduce inflammation
E. Order a bronchoscopy with transbronchial biopsy
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Which of the following organs is located in the left hypochondriac region?

A. Sigmoid colon
B. Appendix
C. Spleen
D. Urinary bladder
E. Gallbladder
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Ovarian Cyst
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 28-year-old female presents with right lower quadrant pain for 3 days. She denies fever, vomiting, or vaginal discharge. Her last menstrual period was 2 weeks ago. The shown CT was performed. What is the MOST likely diagnosis?

A. Endometrioma
B. Corpus luteum cyst
C. Mature cystic teratoma
D. Tubo-ovarian abscess
E. Ovarian torsion
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A 32-year-old woman presents to her general practitioner with a 3-month history of intermittent abdominal pain and bloating. She reports that the pain is crampy, occurs mainly in the lower abdomen, and is often relieved by defecation. She also notes a change in her bowel habits, alternating between constipation and diarrhea. She denies any weight loss, fever, or blood in her stool. Her medical history is unremarkable, and she is not on any medications. On examination, her abdomen is soft with mild tenderness in the lower quadrants but no palpable masses. Blood tests, including a complete blood count and C-reactive protein, are normal. What is the most appropriate next step in the management of this patient?

A. Colonoscopy
B. Reassurance and dietary modification
C. Stool culture
D. Lactose hydrogen breath test
E. Abdominal CT scan
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 35-year-old man presents to his general practitioner reporting a lesion on his nose that he first noticed approximately three months ago. He describes it as initially resembling a persistent pimple, but notes it has not resolved and appears to be slowly increasing in size. He denies any associated pain, itching, or bleeding from the site. His past medical history is unremarkable, and he is not currently taking any regular medications. He works outdoors in a role involving significant sun exposure but admits to inconsistent use of sun protection measures. On physical examination, his vital signs are within normal limits. The lesion in question is located on his nose and has the appearance shown in the accompanying image. No other suspicious skin lesions are identified elsewhere on his body, and regional lymph nodes are not palpable. Considering the clinical presentation and the appearance of the lesion depicted, what is the most appropriate initial step in the management of this patient?

A. Perform a punch biopsy of the lesion for histological examination.
B. Arrange an urgent ultrasound scan of the nose and regional lymph nodes to assess for depth and spread.
C. Prescribe a course of topical antibiotic cream and review in two weeks.
D. Advise the patient to monitor the lesion for further changes and return in three months if it persists or grows.
E. Initiate treatment with a high-potency topical corticosteroid cream twice daily.
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman attends her routine mammogram. She has no palpable lumps or skin changes. Her previous mammograms have been normal. The provided image is from the current study. Which of the following is the MOST appropriate next step in management?

A. Stereotactic core biopsy
B. Excisional biopsy
C. Reassurance and routine screening in 2 years
D. Ultrasound of the breast
E. MRI of the breast
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 55-year-old man presents to his GP with a lesion on his nose that he first noticed about 6 months ago. It has gradually increased in size but is not painful or itchy. He has no significant past medical history and takes no regular medications. On examination, vital signs are stable. The image shows the lesion. Based on the appearance of this lesion, what is the most appropriate next step in management?

A. Advise observation and review in 6 months.
B. Perform an excisional biopsy for histological examination.
C. Refer urgently to a dermatologist for Mohs surgery.
D. Prescribe a course of topical antibiotic cream.
E. Arrange for cryotherapy in the clinic.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents with LLQ pain and fever. The provided image was obtained. What is the most appropriate initial management?

A. Surgical consultation for possible resection
B. Oral antibiotics and outpatient follow-up
C. Colonoscopy to rule out malignancy
D. Stool culture to rule out infectious colitis
E. IV antibiotics and admission for observation
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old woman presents with 3 days of left lower quadrant pain. She reports mild nausea but no vomiting or fever. On examination, she is afebrile, BP 130/80, HR 78, O2 sat 98% on air. There is localised tenderness in the LLQ. Bloods show WCC 13.2, CRP 45. A CT scan is performed. Considering the clinical presentation and the findings demonstrated in the image, what is the most appropriate initial management plan?

A. Discharge with analgesia and advice to return if symptoms worsen, without antibiotics.
B. Outpatient management with oral antibiotics and analgesia.
C. Admission for intravenous antibiotics and observation.
D. Urgent colonoscopy to assess the extent of disease.
E. Surgical consultation for potential colectomy.
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 59-year-old male presents with a painful right groin bulge that has progressively worsened over the past week. He denies fever, chills, nausea, or vomiting. Vitals are stable. The provided image was obtained. What is the MOST appropriate next step?

A. Prescribe analgesics and discharge with surgical follow-up
B. Order a bowel preparation
C. Attempt manual reduction with sedation
D. Initiate broad-spectrum antibiotics
E. Surgical consultation for operative management
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 48-year-old man presents with a 2-year history of progressive, tender breast enlargement causing significant distress. Initial investigations including liver function tests, renal function tests, and basic hormonal assays (LH, FSH, testosterone, oestradiol) were largely within normal limits, except for a mildly elevated oestradiol. He takes no regular medications and denies recreational drug use. He is otherwise well and his physical examination is unremarkable apart from the findings shown in the image. Considering the clinical presentation and the findings, what is the most appropriate next step in his management?

A. Order a CT scan of the abdomen and pelvis to exclude occult malignancy.
B. Initiate a trial of tamoxifen for 3-6 months.
C. Reassure the patient that this is benign and requires no further intervention.
D. Referral to a plastic or general surgeon for consideration of reduction mammoplasty.
E. Repeat hormonal assays including prolactin and hCG.
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A 55-year-old non-smoker with no known comorbidities has a consistent office BP of 155/98 mmHg. His 10-year CVD risk is calculated as low. According to Australian guidelines, what is the most appropriate initial management?

A. Recommend lifestyle modifications and review in 3-6 months
B. Investigate for secondary causes of hypertension
C. Initiate single antihypertensive therapy
D. Refer for ambulatory blood pressure monitoring
E. Initiate dual antihypertensive therapy
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A patient on warfarin presents with leg pain. INR is 3.5. Given the image, what is the MOST appropriate next step?

A. Stop warfarin and administer vitamin K
B. Elevate the leg and apply warm compresses
C. Continue warfarin at the same dose
D. Apply topical corticosteroids
E. Start heparin and continue warfarin
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 58-year-old male presents to the emergency department complaining of right groin pain that started approximately 6 hours ago. He reports noticing a bulge in his groin for several months, which he could usually push back in. However, today he is unable to reduce it, and the pain has become progressively severe. He denies any fever, nausea, or vomiting. His past medical history includes hypertension and hyperlipidemia, both well-controlled with medications. On examination, his vital signs are stable: blood pressure 130/80 mmHg, heart rate 80 bpm, respiratory rate 16 bpm, and temperature 37.0°C. Abdominal examination is benign. Examination of the groin reveals the finding shown in the image. The area is tender to palpation. Which of the following is the MOST appropriate next step in the management of this patient?

A. Surgical consultation for emergent repair
B. Ultrasound of the groin to rule out testicular torsion
C. Prescription for a truss and referral to a general surgeon for elective repair
D. CT scan of the abdomen and pelvis with intravenous contrast
E. Trial of manual reduction with sedation and analgesia
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male with a history of hypertension and hyperlipidemia presents for a routine follow-up. He is asymptomatic. A contrast-enhanced CT abdomen, axial view shown, was performed as part of a screening protocol. What is the MOST appropriate next step?

A. Initiate beta-blocker therapy
B. Prescribe a statin for lipid management
C. Start aspirin for antiplatelet therapy
D. Repeat imaging in 6-12 months
E. Refer for immediate surgical repair
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with abdominal distension and obstipation. An upright abdominal X-ray is performed. What is the MOST appropriate next step in management?

A. Stool softeners
B. Colonoscopy
C. Barium enema
D. Increase oral fluid intake
E. Surgical consultation
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A 45-year-old man presents to the clinic with a 3-month history of fatigue, weight loss, and abdominal pain. He has a history of type 2 diabetes and hypertension. On examination, he has a palpable mass in the left upper quadrant of the abdomen. Laboratory tests reveal anemia and elevated serum lactate dehydrogenase (LDH). A CT scan of the abdomen shows splenomegaly and multiple hypodense lesions in the spleen. What is the most likely diagnosis?

A. Splenic lymphoma
B. Renal cell carcinoma with splenic metastasis
C. Chronic pancreatitis
D. Infectious mononucleosis
E. Portal hypertension
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash on her elbows, knees, and scalp for the past 6 months. She reports that the itching is worse at night and after hot showers. She has tried over-the-counter hydrocortisone cream without relief. On examination, the GP notes symmetrical, excoriated papules and plaques on the extensor surfaces of her elbows and knees, as well as some scaling on her scalp. The patient also mentions a history of recurrent mouth ulcers. Which of the following is the MOST appropriate initial investigation to confirm the suspected diagnosis?

A. Skin biopsy for histopathology and direct immunofluorescence
B. Allergy testing (skin prick or RAST) for common environmental allergens
C. Full blood count (FBC) and liver function tests (LFTs)
D. Potassium hydroxide (KOH) examination of skin scrapings
E. IgA anti-endomysial antibody (EMA) and IgA tissue transglutaminase (tTG) antibody testing
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A 28-year-old woman presents to the clinic with a 3-day history of fever, sore throat, and difficulty swallowing. She has no significant past medical history and is not on any medications. On examination, she has swollen, tender anterior cervical lymph nodes and erythematous tonsils with white exudates. A rapid antigen detection test for group A Streptococcus is positive. What is the most appropriate treatment for her condition?

A. Azithromycin
B. Clindamycin
C. Penicillin V
D. Ceftriaxone
E. Amoxicillin
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 28-year-old female presents to her general practitioner with a 6-month history of intermittent abdominal pain, predominantly in the right lower quadrant. She describes the pain as cramping and associated with occasional episodes of non-bloody diarrhea. She denies fever, weight loss, or recent travel. Her past medical history is significant for well-controlled asthma, for which she uses an inhaled corticosteroid as needed. Physical examination reveals mild tenderness to palpation in the right lower quadrant, but is otherwise unremarkable. Bowel sounds are normal. Initial laboratory investigations, including a complete blood count and comprehensive metabolic panel, are within normal limits. Stool studies for ova and parasites, bacterial culture, and Clostridium difficile toxin are negative. Given her persistent symptoms, the GP refers her for further evaluation. A CT enterography is performed, and relevant images are shown. Based on the clinical presentation and imaging findings, which of the following is the MOST likely long-term complication this patient is at increased risk of developing?

A. Toxic megacolon
B. Fulminant colitis
C. Small bowel obstruction
D. Erosive esophagitis
E. Primary sclerosing cholangitis
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 32-year-old male, recent immigrant from a high-TB prevalence country, presents with a persistent cough and night sweats for the past two months. He denies fever or weight loss. Physical examination is unremarkable except for mild scattered rhonchi on auscultation. Sputum cultures are negative for acid-fast bacilli. A PET-CT scan of the chest is performed, the axial view is shown. Given the clinical context and imaging findings, what is the MOST appropriate next step in management?

A. Schedule a follow-up chest X-ray in 6 weeks to monitor for changes
B. Repeat sputum cultures for acid-fast bacilli with liquid media
C. Order a bronchoscopy with transbronchial biopsy of the lesion
D. Initiate a multi-drug anti-tuberculosis therapy regimen
E. Prescribe a course of broad-spectrum antibiotics for presumed bacterial pneumonia
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old man presents with bilateral breast enlargement, as shown. He denies pain or nipple discharge. What is the MOST likely underlying cause?

A. Liver cirrhosis
B. Medication side effect
C. Hyperthyroidism
D. Klinefelter syndrome
E. Testicular cancer
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 50-year-old man presents with a slowly growing, asymptomatic nasal lesion. He reports no trauma or fever. Examination reveals the image shown. What is the MOST likely long-term outcome if left untreated?

A. Transformation to squamous cell carcinoma
B. Local tissue destruction
C. Metastatic spread
D. Spontaneous resolution
E. Development of systemic lupus erythematosus
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A 45-year-old man presents to the clinic with a 3-month history of persistent cough, night sweats, and weight loss. He has a history of smoking and works as a miner. On examination, he has decreased breath sounds and dullness to percussion over the right upper lobe. A chest X-ray shows a cavitary lesion in the right upper lobe. What is the most likely diagnosis?

A. Pulmonary tuberculosis
B. Chronic obstructive pulmonary disease (COPD)
C. Pneumonia
D. Lung cancer
E. Sarcoidosis
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Which of the following organs is located primarily in the left upper quadrant (LUQ) of the abdomen?

A. Appendix
B. Gallbladder
C. Right kidney
D. Spleen
E. Sigmoid colon
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 45-year-old male presents with a painless lesion on his nose that has been present for several months. He denies any trauma or recent illness. Examination reveals the image shown. What is the MOST appropriate initial management?

A. Observation with serial photography
B. Topical antifungal cream
C. Topical corticosteroid application
D. Biopsy for histopathological examination
E. Cryotherapy
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A 52-year-old woman presents to her general practitioner with fatigue, increased thirst, and frequent urination over the past three months. She has a history of hypertension and hyperlipidemia, managed with lisinopril and atorvastatin. Her BMI is 32 kg/m². On examination, her blood pressure is 140/85 mmHg, and her heart rate is 78 bpm. Laboratory tests reveal a fasting plasma glucose of 8.5 mmol/L and an HbA1c of 7.2%. She is concerned about her risk of complications and asks about the best initial management strategy. Considering Australian guidelines, what is the most appropriate next step in managing her condition?

A. Initiate metformin therapy
B. Advise lifestyle modifications only
C. Prescribe a sulfonylurea
D. Refer to an endocrinologist immediately
E. Start insulin therapy
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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 68-year-old woman presents with a persistent rash following a mastectomy 5 years prior. What is the MOST appropriate next step in management?

A. Skin biopsy
B. Reassurance and observation
C. Topical corticosteroids
D. Mammogram of the contralateral breast
E. Excisional biopsy with wide margins
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old male presents with bilateral breast enlargement for 6 months. He denies pain, discharge, or skin changes. He reports taking saw palmetto for BPH. Examination reveals the findings in the image. What is the MOST likely cause?

A. Hyperthyroidism
B. Testicular cancer
C. Cirrhosis
D. Idiopathic
E. Medication side effect
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A 60-year-old man presents to his GP with a 3-month history of fatigue, weight loss, and night sweats. He has a history of smoking and hypertension. On examination, he has palpable lymphadenopathy in the cervical and axillary regions. Blood tests reveal anemia and elevated lactate dehydrogenase (LDH). What is the most appropriate next step in the investigation of this patient?

A. PET scan
B. Excisional lymph node biopsy
C. CT scan of the chest and abdomen
D. Fine needle aspiration of the lymph node
E. Bone marrow biopsy
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A 60-year-old Aboriginal man presents for a routine check-up. He has a history of smoking and lives in a remote community. Which screening is MOST important, considering higher prevalence in this population?

A. PSA
B. Mammography
C. Albuminuria
D. Colonoscopy
E. Thyroid function tests
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 62-year-old male presents with a 6-month history of a painless swelling in his right groin, visible especially when standing. Examination reveals the finding in the image. The mass reduces when lying down. What is the MOST appropriate initial management?

A. Prescription of a truss support
B. Referral for physiotherapy
C. Referral for elective surgical repair
D. Urgent surgical consultation
E. Reassurance and observation
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66-year-old man, smoker with mild COPD, on salbutamol and tiotropium, confused regarding usage. Back for GPMP. Care plan?

A. Recommend zoster and pneumococcal vaccines.
B. Increase salbutamol dose.
C. Advise to cut down on smoking.
D. Recommend flu, COVID, and pneumococcal vaccines.
E. Refer for pulmonary function tests.
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A 50-year-old man presents to the general practice with a 3-month history of persistent heartburn and regurgitation, especially after meals. He has tried over-the-counter antacids with minimal relief. He denies any weight loss, dysphagia, or gastrointestinal bleeding. What is the most appropriate next step in the management of this patient?

A. Prescribe H2 receptor antagonists
B. Refer to a gastroenterologist
C. Order an upper endoscopy
D. Advise dietary modifications only
E. Start a proton pump inhibitor
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 70-year-old male with a history of smoking presents for a routine check-up. The image is taken. What is the recommended surveillance interval?

A. No further imaging required
B. Initiate statin therapy and monitor annually
C. Repeat imaging in 6-12 months
D. Immediate surgical consultation
E. Repeat imaging in 3 years
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A 45-year-old man presents to his general practitioner with a 3-month history of persistent cough and occasional wheezing. He is a non-smoker and works as a carpenter. He reports that his symptoms worsen at work and improve on weekends. He has no significant past medical history and is not on any medications. What is the most likely diagnosis?

A. Viral upper respiratory tract infection
B. Pulmonary fibrosis
C. Chronic obstructive pulmonary disease (COPD)
D. Gastroesophageal reflux disease (GERD)
E. Occupational asthma
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A 32-year-old male presents to his general practitioner with persistent anal pain and bleeding on defecation for the past 8 months. He reports a cycle of pain, relief after bowel movements, followed by throbbing pain lasting several hours. Examination reveals a visible anal fissure at the 6 o'clock position, along with a skin tag. Which of the following is the MOST appropriate next step in management, according to Australian guidelines?

A. Topical glyceryl trinitrate (GTN) ointment and stool softeners
B. Fibre supplementation and sitz baths
C. Botulinum toxin injection into the internal anal sphincter
D. Excision of the fissure and skin tag with advancement flap
E. Lateral internal sphincterotomy
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